Gene description for ZFP91
Gene name ZFP91 zinc finger protein
Gene symbol ZFP91
Other names/aliases DMS-8
DSM-8
FKSG11
PZF
ZFP-91
ZNF757
Species Homo sapiens
 Database cross references - ZFP91
ExoCarta ExoCarta_80829
Vesiclepedia VP_80829
Entrez Gene 80829
HGNC 14983
UniProt Q96JP5  
 ZFP91 identified in exosomes derived from the following tissue/cell type
Endothelial cells 26027894    
 Gene ontology annotations for ZFP91
Molecular Function
    ubiquitin-protein transferase activity GO:0004842 IDA
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
Biological Process
    regulation of transcription by RNA polymerase II GO:0006357 IBA
    activation of NF-kappaB-inducing kinase activity GO:0007250 IDA
    protein K63-linked ubiquitination GO:0070534 IDA
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleoplasm GO:0005654 IDA
    nucleolus GO:0005730 IDA
 Experiment description of studies that identified ZFP91 in exosomes
1
Experiment ID 226
MISEV standards
EM
Biophysical techniques
GAPDH|CD9|FLOT1
Enriched markers
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting
Authors Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for ZFP91
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RPSAP58 388524
Affinity Capture-MS Homo sapiens
2 PRM2  
Affinity Capture-MS Homo sapiens
3 SENP3 26168
Affinity Capture-MS Homo sapiens
4 H1FNT  
Affinity Capture-MS Homo sapiens
5 CLEC3A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 PAEP  
Affinity Capture-MS Homo sapiens
7 USP5 8078
Co-fractionation Homo sapiens
8 RPS19 6223
Affinity Capture-MS Homo sapiens
9 BRD2  
Affinity Capture-MS Homo sapiens
10 RPL14 9045
Affinity Capture-MS Homo sapiens
11 RIPK1 8737
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
12 RPS3 6188
Affinity Capture-MS Homo sapiens
13 RNPS1 10921
Affinity Capture-MS Homo sapiens
14 CEP70  
Two-hybrid Homo sapiens
15 UBE2O 63893
Affinity Capture-MS Homo sapiens
16 CHCHD2  
Affinity Capture-MS Homo sapiens
17 BHLHA15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 CHCHD10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 ANOS1 3730
Affinity Capture-MS Homo sapiens
20 BRPF3  
Affinity Capture-MS Homo sapiens
21 C1qbp 12261
Affinity Capture-MS Mus musculus
22 MAGED2 10916
Affinity Capture-MS Homo sapiens
23 Set 56086
Affinity Capture-MS Mus musculus
24 TNFRSF13B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 UTP20 27340
Co-fractionation Homo sapiens
26 FBL 2091
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 FTSJ1 24140
Affinity Capture-MS Homo sapiens
28 RPL19 6143
Affinity Capture-MS Homo sapiens
29 GSK3B 2932
Affinity Capture-MS Homo sapiens
30 NOTCH2 4853
Affinity Capture-MS Homo sapiens
31 LIN28A  
Affinity Capture-MS Homo sapiens
32 KLF16  
Proximity Label-MS Homo sapiens
33 E2F4  
Affinity Capture-MS Homo sapiens
34 DDX21 9188
Affinity Capture-MS Homo sapiens
35 ZNF526  
Two-hybrid Homo sapiens
36 RPS10 6204
Affinity Capture-MS Homo sapiens
37 YBX2 51087
Affinity Capture-MS Homo sapiens
38 Ppp2ca 19052
Affinity Capture-MS Mus musculus
39 POU6F2  
Two-hybrid Homo sapiens
40 ZFP41  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
41 FAM9A  
Two-hybrid Homo sapiens
42 SLX4  
Affinity Capture-MS Homo sapiens
43 RPL31 6160
Affinity Capture-MS Homo sapiens
44 DDX54 79039
Affinity Capture-MS Homo sapiens
45 CTR9 9646
Affinity Capture-MS Homo sapiens
46 CEBPA  
Proximity Label-MS Homo sapiens
47 CD3EAP  
Proximity Label-MS Homo sapiens
48 HSPA5 3309
Co-fractionation Homo sapiens
49 ZBTB2 57621
Affinity Capture-MS Homo sapiens
50 AURKAIP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 RPS2 6187
Affinity Capture-MS Homo sapiens
52 ECD  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
53 SMARCA5 8467
Co-fractionation Homo sapiens
54 TSPYL5  
Affinity Capture-MS Homo sapiens
55 TSPYL2  
Two-hybrid Homo sapiens
56 SRSF1 6426
Affinity Capture-MS Homo sapiens
57 RPS6 6194
Affinity Capture-MS Homo sapiens
58 RPL3 6122
Affinity Capture-MS Homo sapiens
59 HNRNPA1 3178
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
60 NOM1  
Affinity Capture-MS Homo sapiens
61 SET 6418
Affinity Capture-MS Homo sapiens
62 GNLY  
Affinity Capture-MS Homo sapiens
63 ZNF653  
Affinity Capture-MS Homo sapiens
64 HNRNPAB 3182
Affinity Capture-Western Homo sapiens
65 RNF2  
Affinity Capture-MS Homo sapiens
66 Nedd1  
Affinity Capture-MS Mus musculus
67 Mad2l1 56150
Affinity Capture-MS Mus musculus
68 NEUROG3  
Affinity Capture-MS Homo sapiens
69 BRD3 8019
Affinity Capture-MS Homo sapiens
70 RPL13 6137
Affinity Capture-MS Homo sapiens
71 RELA 5970
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
72 DDX50 79009
Affinity Capture-MS Homo sapiens
73 RPL37 6167
Affinity Capture-MS Homo sapiens
74 MAP3K14  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
75 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
76 TP53BP2  
Two-hybrid Homo sapiens
77 CENPA  
Co-purification Homo sapiens
78 TP53 7157
Affinity Capture-MS Homo sapiens
79 DLG3 1741
Affinity Capture-MS Homo sapiens
80 HSPA8 3312
Co-fractionation Homo sapiens
81 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
82 GBA 2629
Affinity Capture-MS Homo sapiens
83 H2AFB3  
Affinity Capture-MS Homo sapiens
84 MKI67  
Affinity Capture-MS Homo sapiens
85 PRDM5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
86 NEIL1  
Affinity Capture-MS Homo sapiens
87 RPL7A 6130
Affinity Capture-MS Homo sapiens
88 RPS8 6202
Affinity Capture-MS Homo sapiens
89 HNRNPF 3185
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
90 ELF2  
Proximity Label-MS Homo sapiens
91 RPL23A 6147
Affinity Capture-MS Homo sapiens
92 RPL36AL 6166
Affinity Capture-MS Homo sapiens
93 LUC7L 55692
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
94 HIST1H2AE 3012
Affinity Capture-MS Homo sapiens
95 EP300 2033
Affinity Capture-MS Homo sapiens
96 CASQ2 845
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ZFP91 is involved
No pathways found





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