Gene description for ZFP91
Gene name ZFP91 zinc finger protein
Gene symbol ZFP91
Other names/aliases DMS-8
DSM-8
FKSG11
PZF
ZFP-91
ZNF757
Species Homo sapiens
 Database cross references - ZFP91
ExoCarta ExoCarta_80829
Entrez Gene 80829
HGNC 14983
UniProt Q96JP5  
 ZFP91 identified in exosomes derived from the following tissue/cell type
Endothelial cells 26027894    
 Gene ontology annotations for ZFP91
Molecular Function
    metal ion binding GO:0046872 IEA
    ligase activity GO:0016874 IEA
    nucleic acid binding GO:0003676 IEA
    ubiquitin-protein transferase activity GO:0004842 IDA
Biological Process
    activation of NF-kappaB-inducing kinase activity GO:0007250 IDA
    protein K63-linked ubiquitination GO:0070534 IDA
Subcellular Localization
    nucleus GO:0005634 IEA
 Experiment description of studies that identified ZFP91 in exosomes
1
Experiment ID 226
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD9|FLOT1
EV Membrane markers
LMNA|H2AFX|ATP5A1|TOMM20
EV Negative markers
EV Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting
Authors Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for ZFP91
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ZFP91 is involved
No pathways found





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