Gene description for DDX50
Gene name DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
Gene symbol DDX50
Other names/aliases GU2
GUB
RH-II/GuB
mcdrh
Species Homo sapiens
 Database cross references - DDX50
ExoCarta ExoCarta_79009
Entrez Gene 79009
HGNC 17906
MIM 610373
UniProt Q9BQ39  
 DDX50 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for DDX50
Molecular Function
    poly(A) RNA binding GO:0044822 IDA
    ATP binding GO:0005524 IEA
    ATP-dependent RNA helicase activity GO:0004004 IBA
Biological Process
    RNA secondary structure unwinding GO:0010501 IBA
Subcellular Localization
    nucleolus GO:0005730 IDA
    membrane GO:0016020 IDA
    plasma membrane GO:0005886 IDA
 Experiment description of studies that identified DDX50 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for DDX50
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which DDX50 is involved
No pathways found





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