Gene description for CHD4
Gene name chromodomain helicase DNA binding protein 4
Gene symbol CHD4
Other names/aliases CHD-4
Mi-2b
Mi2-BETA
Species Homo sapiens
 Database cross references - CHD4
ExoCarta ExoCarta_1108
Vesiclepedia VP_1108
Entrez Gene 1108
HGNC 1919
MIM 603277
UniProt Q14839  
 CHD4 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for CHD4
Molecular Function
    transcription coregulator binding GO:0001221 IPI
    DNA binding GO:0003677 IBA
    chromatin binding GO:0003682 IBA
    DNA clamp loader activity GO:0003689 IEA
    transcription corepressor activity GO:0003714 IDA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    zinc ion binding GO:0008270 TAS
    four-way junction helicase activity GO:0009378 IEA
    ATP hydrolysis activity GO:0016887 IBA
    ATP hydrolysis activity GO:0016887 IDA
    nucleosomal DNA binding GO:0031492 HDA
    double-stranded DNA helicase activity GO:0036121 IEA
    histone binding GO:0042393 IBA
    histone deacetylase binding GO:0042826 IPI
    RNA polymerase II-specific DNA-binding transcription factor binding GO:0061629 IPI
    forked DNA-dependent helicase activity GO:0061749 IEA
    cohesin loader activity GO:0061775 IEA
    chromatin extrusion motor activity GO:0140584 IEA
    ATP-dependent chromatin remodeler activity GO:0140658 IBA
    ATP-dependent chromatin remodeler activity GO:0140658 IDA
    ATP-dependent H3-H4 histone complex chaperone activity GO:0140665 IEA
    ATP-dependent H2AZ histone chaperone activity GO:0140849 IEA
    single-stranded 3'-5' DNA helicase activity GO:1990518 IEA
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IEA
    double-strand break repair via homologous recombination GO:0000724 IMP
    chromatin remodeling GO:0006338 HDA
    chromatin remodeling GO:0006338 IBA
    chromatin remodeling GO:0006338 IDA
    negative regulation of gene expression GO:0010629 IDA
    negative regulation of gene expression GO:0010629 IGI
    DNA duplex unwinding GO:0032508 IEA
    regulation of cell fate specification GO:0042659 NAS
    negative regulation of DNA-templated transcription GO:0045892 NAS
    positive regulation of DNA-templated transcription GO:0045893 NAS
    regulation of synapse assembly GO:0051963 IEA
    terminal button organization GO:0072553 IEA
    chromatin looping GO:0140588 IEA
    regulation of stem cell differentiation GO:2000736 NAS
Subcellular Localization
    chromosome, telomeric region GO:0000781 IDA
    chromatin GO:0000785 HDA
    chromatin GO:0000785 IBA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 IDA
    centrosome GO:0005813 IDA
    membrane GO:0016020 HDA
    NuRD complex GO:0016581 IBA
    NuRD complex GO:0016581 IDA
    NuRD complex GO:0016581 NAS
    protein-containing complex GO:0032991 HDA
    RNA polymerase II transcription regulator complex GO:0090575 IDA
    site of DNA damage GO:0090734 IDA
    cerebellar granule cell to Purkinje cell synapse GO:0150048 IEA
 Experiment description of studies that identified CHD4 in sEVs
1
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 498
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 207
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 208
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 407
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 405
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 417
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 411
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 488
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
26
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 413
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 211
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 212
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
31
Experiment ID 406
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 415
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
34
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
35
Experiment ID 408
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 409
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 416
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
38
Experiment ID 410
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
39
Experiment ID 217
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CHD4
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HIST2H2BE 8349
Affinity Capture-MS Homo sapiens
2 HDAC2 3066
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
3 KPNA1 3836
Affinity Capture-MS Homo sapiens
4 TOP2B 7155
Affinity Capture-MS Homo sapiens
5 NFATC1 4772
Affinity Capture-MS Homo sapiens
6 ACTC1 70
Proximity Label-MS Homo sapiens
7 SMARCE1 6605
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
8 KIF20A 10112
Affinity Capture-MS Homo sapiens
9 BRD2  
Affinity Capture-MS Homo sapiens
10 UBC 7316
Affinity Capture-MS Homo sapiens
11 CSNK2A1 1457
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
12 PARK7 11315
Affinity Capture-MS Homo sapiens
13 SOX2  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
14 PMF1  
Affinity Capture-MS Homo sapiens
15 APEX1 328
Affinity Capture-RNA Homo sapiens
16 WDR76  
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
17 CBX1 10951
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 CRNKL1 51340
Affinity Capture-MS Homo sapiens
19 MTF2  
Affinity Capture-MS Homo sapiens
20 CHAF1A  
Affinity Capture-MS Homo sapiens
21 KIF23 9493
Affinity Capture-MS Homo sapiens
22 MATR3 9782
Co-fractionation Homo sapiens
23 RNF8  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
24 CDK2AP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 DDX24 57062
Affinity Capture-MS Homo sapiens
26 FBL 2091
Affinity Capture-MS Homo sapiens
27 SMC2 10592
Co-fractionation Homo sapiens
28 DYNLL1 8655
Affinity Capture-MS Homo sapiens
29 MECP2 4204
Affinity Capture-MS Homo sapiens
30 MLXIPL  
Affinity Capture-MS Homo sapiens
31 MTA2 9219
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
32 TCOF1 6949
Affinity Capture-MS Homo sapiens
33 CTBP1 1487
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 HIST1H2AG 8969
Affinity Capture-MS Homo sapiens
35 C17orf49 124944
Affinity Capture-MS Homo sapiens
36 ZMYM3  
Affinity Capture-MS Homo sapiens
37 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
38 UBASH3B 84959
Affinity Capture-MS Homo sapiens
39 Srp72  
Affinity Capture-MS Mus musculus
40 MYH9 4627
Co-fractionation Homo sapiens
41 SLX4  
Affinity Capture-MS Homo sapiens
42 RPL31 6160
Cross-Linking-MS (XL-MS) Homo sapiens
43 CBX5 23468
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 BANF1 8815
Affinity Capture-MS Homo sapiens
45 ENO1 2023
Cross-Linking-MS (XL-MS) Homo sapiens
46 ZNF581  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 HECTD1 25831
Affinity Capture-MS Homo sapiens
48 CHD5 26038
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
49 DSN1 79980
Affinity Capture-MS Homo sapiens
50 TWIST1  
Reconstituted Complex Homo sapiens
51 HIST1H2BL 8340
Cross-Linking-MS (XL-MS) Homo sapiens
52 NASP 4678
Co-fractionation Homo sapiens
53 STMN2  
Affinity Capture-MS Homo sapiens
54 SNAI1  
Affinity Capture-Western Homo sapiens
55 LMNB1 4001
Co-fractionation Homo sapiens
56 SIRT7  
Affinity Capture-MS Homo sapiens
57 EPAS1  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
58 TAL1  
Affinity Capture-MS Homo sapiens
59 POLD3  
Affinity Capture-Western Homo sapiens
60 CUL3 8452
Affinity Capture-MS Homo sapiens
61 RAD18  
Affinity Capture-MS Homo sapiens
62 MTNR1A  
Two-hybrid Homo sapiens
63 RBBP4 5928
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
64 BAZ2A  
Affinity Capture-MS Homo sapiens
65 SPEN 23013
Affinity Capture-MS Homo sapiens
66 RPA3 6119
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
67 ZMYND8 23613
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 PHF5A 84844
Affinity Capture-Western Homo sapiens
69 BRD4 23476
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
70 ZNF687  
Affinity Capture-MS Homo sapiens
71 HAT1 8520
Affinity Capture-MS Homo sapiens
72 PML 5371
Affinity Capture-Western Homo sapiens
73 NFATC2  
Affinity Capture-MS Homo sapiens
74 SUPT16H 11198
Affinity Capture-MS Homo sapiens
75 PYHIN1  
Affinity Capture-MS Homo sapiens
76 DYNLL2 140735
Affinity Capture-MS Homo sapiens
77 WDR77 79084
Affinity Capture-MS Homo sapiens
78 RBM25 58517
Co-fractionation Homo sapiens
79 MTA1 9112
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 KPNA6 23633
Affinity Capture-MS Homo sapiens
81 RUVBL2 10856
Affinity Capture-MS Homo sapiens
82 SALL1 6299
Affinity Capture-MS Homo sapiens
83 CHAMP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 OGG1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
85 NCL 4691
Affinity Capture-MS Homo sapiens
86 PCGF6  
Affinity Capture-MS Homo sapiens
87 EHMT1  
Affinity Capture-MS Homo sapiens
88 SNW1 22938
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
89 CWC22 57703
Affinity Capture-MS Homo sapiens
90 PWWP2A  
Affinity Capture-MS Homo sapiens
91 DNMT1 1786
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
92 HIST1H2BD 3017
Cross-Linking-MS (XL-MS) Homo sapiens
93 ATR  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
94 AFG3L2 10939
Affinity Capture-MS Homo sapiens
95 ZFHX4  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
96 CLIP1 6249
Co-fractionation Homo sapiens
97 MAGEA3  
Affinity Capture-MS Homo sapiens
98 RPA2 6118
Affinity Capture-MS Homo sapiens
99 HIST1H2BG 8339
Proximity Label-MS Homo sapiens
100 NOP56 10528
Affinity Capture-MS Homo sapiens
101 GBX2  
Affinity Capture-MS Homo sapiens
102 ATM 472
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
103 ZFHX3  
Affinity Capture-MS Homo sapiens
104 NOLC1 9221
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
105 ZNF524  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
106 PRC1 9055
Affinity Capture-MS Homo sapiens
107 OBSL1 23363
Affinity Capture-MS Homo sapiens
108 MBD3L2  
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
109 NR4A1  
Affinity Capture-MS Homo sapiens
110 ZNF644  
Affinity Capture-MS Homo sapiens
111 WIZ 58525
Affinity Capture-MS Homo sapiens
112 PHF1  
Affinity Capture-MS Homo sapiens
113 SETD1A 9739
Affinity Capture-MS Homo sapiens
114 MAD2L1 4085
Affinity Capture-MS Homo sapiens
115 HIST2H2AB 317772
Affinity Capture-MS Homo sapiens
116 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
117 WHSC1 7468
Proximity Label-MS Homo sapiens
118 ACIN1 22985
Affinity Capture-MS Homo sapiens
119 NOTCH1 4851
Affinity Capture-MS Homo sapiens
120 NELFE 7936
Affinity Capture-MS Homo sapiens
121 AIM2  
Affinity Capture-MS Homo sapiens
122 ZBTB46  
Affinity Capture-MS Homo sapiens
123 BPTF 2186
Affinity Capture-MS Homo sapiens
124 TEAD2  
Affinity Capture-MS Homo sapiens
125 MBD2 8932
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
126 UBTF 7343
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
127 NOL4  
Affinity Capture-MS Homo sapiens
128 RAD21 5885
Affinity Capture-MS Homo sapiens
129 RSL1D1 26156
Affinity Capture-MS Homo sapiens
130 ZCCHC8 55596
Affinity Capture-MS Homo sapiens
131 SMARCAD1  
Affinity Capture-MS Homo sapiens
132 PIP 5304
Affinity Capture-MS Homo sapiens
133 IKZF3  
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
134 PRKAR2A 5576
Co-fractionation Homo sapiens
135 MEX3A  
Affinity Capture-RNA Homo sapiens
136 BTF3 689
Affinity Capture-MS Homo sapiens
137 SLK 9748
Cross-Linking-MS (XL-MS) Homo sapiens
138 IKZF1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
139 HIST3H3 8290
Protein-peptide Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
140 MYC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
141 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
142 EHMT2 10919
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
143 RAI1 10743
Affinity Capture-MS Homo sapiens
144 CUL7 9820
Affinity Capture-MS Homo sapiens
145 BMI1  
Affinity Capture-MS Homo sapiens
146 PGAM1 5223
Cross-Linking-MS (XL-MS) Homo sapiens
147 SUZ12  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
148 GATAD2A 54815
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
149 TAF6 6878
Affinity Capture-MS Homo sapiens
150 PRKCSH 5589
Cross-Linking-MS (XL-MS) Homo sapiens
151 PARP1 142
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
152 H3F3A 3020
Affinity Capture-MS Homo sapiens
153 TP53 7157
Affinity Capture-MS Homo sapiens
154 SALL4  
Affinity Capture-MS Homo sapiens
155 LCORL  
Affinity Capture-MS Homo sapiens
156 DPYSL5  
Affinity Capture-MS Homo sapiens
157 FOXJ2  
Affinity Capture-MS Homo sapiens
158 TRIP12 9320
Affinity Capture-MS Homo sapiens
159 LIN37  
Affinity Capture-MS Homo sapiens
160 NAB2 4665
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
161 NACC2  
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
162 MLLT3 4300
Affinity Capture-MS Homo sapiens
163 MTA3 57504
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
164 KRAS 3845
Negative Genetic Homo sapiens
165 PHF20L1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
166 CCT8L2  
Affinity Capture-MS Homo sapiens
167 Mta2 23942
Affinity Capture-MS Mus musculus
168 CUL4A 8451
Affinity Capture-MS Homo sapiens
169 MIS12  
Affinity Capture-MS Homo sapiens
170 HNRNPC 3183
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
171 GATAD2B 57459
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
172 NOP58 51602
Affinity Capture-MS Homo sapiens
173 USP43  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
174 RPS19BP1  
Affinity Capture-MS Homo sapiens
175 NSL1  
Affinity Capture-MS Homo sapiens
176 HSFY1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
177 PCNT  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
178 VARS 7407
Co-fractionation Homo sapiens
179 SALL3  
Affinity Capture-MS Homo sapiens
180 SMARCA1 6594
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
181 SPAG9 9043
Co-fractionation Homo sapiens
182 ZNF460  
Affinity Capture-MS Homo sapiens
183 PROX1  
Affinity Capture-MS Homo sapiens
184 ITGA4 3676
Affinity Capture-MS Homo sapiens
185 CSNK2B 1460
Affinity Capture-MS Homo sapiens
186 SMARCA2 6595
Affinity Capture-MS Homo sapiens
187 ZNF462  
Affinity Capture-MS Homo sapiens
188 DPEP3 64180
Affinity Capture-MS Homo sapiens
189 RBPJ 3516
Affinity Capture-MS Homo sapiens
190 C15orf59  
Affinity Capture-MS Homo sapiens
191 DPEP2  
Affinity Capture-MS Homo sapiens
192 FOXC1  
Affinity Capture-MS Homo sapiens
193 SHPRH  
Affinity Capture-MS Homo sapiens
194 CBX3 11335
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
195 PARK2  
Affinity Capture-MS Homo sapiens
196 PHF14 9678
Affinity Capture-MS Homo sapiens
197 XRN1 54464
Two-hybrid Homo sapiens
198 SNAI2  
Affinity Capture-Western Homo sapiens
199 SRRT 51593
Affinity Capture-MS Homo sapiens
200 KPNA4 3840
Affinity Capture-MS Homo sapiens
201 POGZ 23126
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
202 NTRK1 4914
Affinity Capture-MS Homo sapiens
203 ARNT 405
Affinity Capture-Western Homo sapiens
204 DNAJA1 3301
Co-fractionation Homo sapiens
205 CDH1 999
Negative Genetic Homo sapiens
206 MYBL2 4605
Affinity Capture-MS Homo sapiens
207 ZNF784  
Affinity Capture-MS Homo sapiens
208 SNRNP27  
Affinity Capture-MS Homo sapiens
209 KPNA5 3841
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
210 H3F3C 440093
Affinity Capture-MS Homo sapiens
211 RBBP6 5930
Affinity Capture-MS Homo sapiens
212 ZBTB2 57621
Affinity Capture-MS Homo sapiens
213 KMT2A  
Affinity Capture-MS Homo sapiens
214 BAZ1B 9031
Affinity Capture-MS Homo sapiens
215 SMARCA5 8467
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
216 H1F0 3005
Affinity Capture-MS Homo sapiens
217 HNRNPCL2 440563
Affinity Capture-MS Homo sapiens
218 SAP30 8819
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
219 DNMT3B  
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
220 LIN9  
Affinity Capture-MS Homo sapiens
221 ZC3H18  
Affinity Capture-MS Homo sapiens
222 PHF6  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
223 TOP1 7150
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
224 GPATCH8  
Affinity Capture-MS Homo sapiens
225 RNF2  
Affinity Capture-MS Homo sapiens
226 FOXQ1  
Affinity Capture-MS Homo sapiens
227 HSPA9 3313
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
228 IKZF2 22807
Affinity Capture-Western Homo sapiens
229 TRPS1  
Affinity Capture-MS Homo sapiens
230 HIF1A 3091
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
231 DZIP3  
Affinity Capture-MS Homo sapiens
232 DDX50 79009
Affinity Capture-MS Homo sapiens
233 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
234 FBXL6  
Affinity Capture-MS Homo sapiens
235 SIN3A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
236 TRAPPC8 22878
Affinity Capture-MS Homo sapiens
237 RPA1 6117
Affinity Capture-MS Homo sapiens
238 PDHA1 5160
Affinity Capture-MS Homo sapiens
239 PBRM1 55193
Affinity Capture-MS Homo sapiens
240 FBXO44  
Affinity Capture-Western Homo sapiens
241 DDX58 23586
Affinity Capture-RNA Homo sapiens
242 MKI67  
Affinity Capture-MS Homo sapiens
243 HMGXB4 10042
Affinity Capture-MS Homo sapiens
244 KDM1A 23028
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
245 TCF20  
Affinity Capture-MS Homo sapiens
246 SERBP1 26135
Affinity Capture-MS Homo sapiens
247 AR 367
Proximity Label-MS Homo sapiens
248 RSF1  
Affinity Capture-MS Homo sapiens
249 SSRP1 6749
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
250 FOXE1  
Affinity Capture-MS Homo sapiens
251 DDX56  
Affinity Capture-MS Homo sapiens
252 EP300 2033
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
253 EIF5 1983
Co-fractionation Homo sapiens
254 CAPN2 824
Co-fractionation Homo sapiens
255 UBE2H 7328
Affinity Capture-MS Homo sapiens
256 MCRS1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
257 RIT1 6016
Negative Genetic Homo sapiens
258 LGR4 55366
Affinity Capture-MS Homo sapiens
259 SUB1 10923
Co-fractionation Homo sapiens
260 DHX8 1659
Affinity Capture-MS Homo sapiens
261 IKZF4  
Affinity Capture-Western Homo sapiens
262 AQR 9716
Affinity Capture-MS Homo sapiens
263 USP36  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
264 KIAA1429 25962
Affinity Capture-MS Homo sapiens
265 TOP2A 7153
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
266 RPS20 6224
Cross-Linking-MS (XL-MS) Homo sapiens
267 PPP1R12A 4659
Co-fractionation Homo sapiens
268 Cdk2ap1  
Affinity Capture-MS Mus musculus
269 TBL1XR1 79718
Co-fractionation Homo sapiens
270 ISY1 57461
Affinity Capture-MS Homo sapiens
271 NR2C2  
Affinity Capture-Western Homo sapiens
272 FBXW7  
Affinity Capture-MS Homo sapiens
273 ZNF512B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
274 H2AFY2 55506
Affinity Capture-MS Homo sapiens
275 HMGA1 3159
Affinity Capture-MS Homo sapiens
276 THRSP  
Affinity Capture-MS Homo sapiens
277 EED  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
278 ZNF219  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
279 NR2C1  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
280 MYCN  
Affinity Capture-MS Homo sapiens
281 CHD3 1107
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
282 CPNE5 57699
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
283 BCL11B  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
284 ESR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
285 H2AFZ 3015
Affinity Capture-MS Homo sapiens
286 ZKSCAN8  
Affinity Capture-MS Homo sapiens
287 RBBP7 5931
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
288 EMD 2010
Affinity Capture-MS Homo sapiens
289 LRIF1  
Affinity Capture-MS Homo sapiens
290 UBE2I 7329
Biochemical Activity Homo sapiens
291 SMARCA4 6597
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
292 FOXK2  
Affinity Capture-MS Homo sapiens
293 ACTL6A 86
Co-fractionation Homo sapiens
294 IFI16 3428
Affinity Capture-MS Homo sapiens
295 SUMO2 6613
Reconstituted Complex Homo sapiens
296 MYH10 4628
Co-fractionation Homo sapiens
297 SUDS3  
Affinity Capture-MS Homo sapiens
298 MBD3 53615
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
299 H2AFY 9555
Affinity Capture-MS Homo sapiens
300 CEBPA  
Proximity Label-MS Homo sapiens
Protein-peptide Homo sapiens
301 PRKACB 5567
Affinity Capture-MS Homo sapiens
302 DAXX  
Affinity Capture-MS Homo sapiens
303 NAB1 4664
Affinity Capture-Western Homo sapiens
304 ZMYM4  
Affinity Capture-MS Homo sapiens
305 BCL11A 53335
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
306 VCAM1 7412
Affinity Capture-MS Homo sapiens
307 NUMA1 4926
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
308 HIST1H3A 8350
Co-localization Homo sapiens
Protein-peptide Homo sapiens
Protein-peptide Homo sapiens
Co-crystal Structure Homo sapiens
Co-crystal Structure Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
309 FANCD2  
Affinity Capture-MS Homo sapiens
310 PNN 5411
Affinity Capture-MS Homo sapiens
311 CTNNB1 1499
Affinity Capture-MS Homo sapiens
312 RAD51B  
Cross-Linking-MS (XL-MS) Homo sapiens
313 FOXG1  
Affinity Capture-MS Homo sapiens
314 ADNP 23394
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
315 MCM4 4173
Co-fractionation Homo sapiens
316 BRMS1L  
Affinity Capture-MS Homo sapiens
317 PRKCI 5584
Co-fractionation Homo sapiens
318 DKC1 1736
Affinity Capture-MS Homo sapiens
319 XRCC6 2547
Proximity Label-MS Homo sapiens
320 HIST1H2BA 255626
Cross-Linking-MS (XL-MS) Homo sapiens
321 TRIM27  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
322 ARID1A 8289
Co-fractionation Homo sapiens
323 BRD3 8019
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
324 ZMYM2  
Affinity Capture-MS Homo sapiens
325 CCDC8  
Affinity Capture-MS Homo sapiens
326 EIF3D 8664
Affinity Capture-MS Homo sapiens
327 Cbx1  
Affinity Capture-MS Mus musculus
328 CXCR3  
Affinity Capture-MS Homo sapiens
329 SIRT6  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
330 ZNF592 9640
Affinity Capture-MS Homo sapiens
331 TSHZ3  
Affinity Capture-MS Homo sapiens
332 SRRM1 10250
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
333 HIST2H2BC 337873
Affinity Capture-MS Homo sapiens
334 SMARCC1 6599
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
335 SAP18 10284
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
336 ADNP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
337 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
338 HDAC1 3065
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
339 CHD4 1108
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
340 CPNE3 8895
Cross-Linking-MS (XL-MS) Homo sapiens
341 Mta1  
Affinity Capture-MS Mus musculus
342 MCPH1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
343 Mbd2  
Affinity Capture-MS Mus musculus
344 EZH2  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
345 PINK1  
Affinity Capture-MS Homo sapiens
346 ZUFSP 221302
Affinity Capture-MS Homo sapiens
347 MBD3L1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
348 CHAF1B  
Affinity Capture-MS Homo sapiens
349 WDHD1  
Co-fractionation Homo sapiens
350 TOP1MT  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which CHD4 is involved
PathwayEvidenceSource
Adipogenesis IEA Reactome
Chromatin modifying enzymes TAS Reactome
Chromatin organization TAS Reactome
Developmental Biology IEA Reactome
Disease TAS Reactome
Epigenetic regulation of gene expression IEA Reactome
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression IEA Reactome
Gene expression (Transcription) IEA Reactome
Gene expression (Transcription) TAS Reactome
Generic Transcription Pathway TAS Reactome
HDACs deacetylate histones TAS Reactome
Infectious disease TAS Reactome
Intracellular signaling by second messengers IEA Reactome
Intracellular signaling by second messengers TAS Reactome
NGF-stimulated transcription TAS Reactome
Nuclear Events (kinase and transcription factor activation) TAS Reactome
PIP3 activates AKT signaling IEA Reactome
PIP3 activates AKT signaling TAS Reactome
Positive epigenetic regulation of rRNA expression IEA Reactome
Potential therapeutics for SARS TAS Reactome
PTEN Regulation IEA Reactome
PTEN Regulation TAS Reactome
Regulation of endogenous retroelements IEA Reactome
Regulation of endogenous retroelements by KRAB-ZFP proteins IEA Reactome
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) IEA Reactome
Regulation of PTEN gene transcription IEA Reactome
Regulation of PTEN gene transcription TAS Reactome
Regulation of TP53 Activity TAS Reactome
Regulation of TP53 Activity through Acetylation TAS Reactome
RNA Polymerase I Promoter Clearance TAS Reactome
RNA Polymerase I Transcription TAS Reactome
RNA Polymerase I Transcription Initiation TAS Reactome
RNA Polymerase II Transcription TAS Reactome
SARS-CoV Infections TAS Reactome
Signal Transduction IEA Reactome
Signal Transduction TAS Reactome
Signaling by NTRK1 (TRKA) TAS Reactome
Signaling by NTRKs TAS Reactome
Signaling by Receptor Tyrosine Kinases TAS Reactome
Transcriptional Regulation by TP53 TAS Reactome
Transcriptional regulation of brown and beige adipocyte differentiation IEA Reactome
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 IEA Reactome
Viral Infection Pathways TAS Reactome





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