Gene description for ZNF592
Gene name zinc finger protein 592
Gene symbol ZNF592
Other names/aliases CAMOS
SCAR5
Species Homo sapiens
 Database cross references - ZNF592
ExoCarta ExoCarta_9640
Vesiclepedia VP_9640
Entrez Gene 9640
HGNC 28986
MIM 613624
UniProt Q92610  
 ZNF592 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for ZNF592
Molecular Function
    DNA binding GO:0003677 IEA
    DNA-binding transcription factor activity GO:0003700 NAS
    protein binding GO:0005515 IPI
    PH domain binding GO:0042731 IEA
    insulin receptor substrate binding GO:0043560 IEA
    metal ion binding GO:0046872 IEA
Biological Process
    regulation of DNA-templated transcription GO:0006355 IEA
    negative regulation of insulin receptor signaling pathway GO:0046627 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
 Experiment description of studies that identified ZNF592 in exosomes
1
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for ZNF592
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CD3EAP  
Proximity Label-MS Homo sapiens
2 GATAD2A 54815
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 SRSF11 9295
Co-fractionation Homo sapiens
4 LLGL2 3993
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 POLR1E  
Proximity Label-MS Homo sapiens
6 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
7 ZBTB2 57621
Affinity Capture-MS Homo sapiens
8 ASF1A 25842
Proximity Label-MS Homo sapiens
9 CSNK2B 1460
Affinity Capture-MS Homo sapiens
10 BRDT  
Affinity Capture-MS Homo sapiens
11 NOTCH2 4853
Affinity Capture-MS Homo sapiens
12 HIST1H2BG 8339
Proximity Label-MS Homo sapiens
13 CD6 923
Affinity Capture-MS Homo sapiens
14 BRD2  
Affinity Capture-MS Homo sapiens
15 CSNK2A1 1457
Affinity Capture-MS Homo sapiens
16 HDAC1 3065
Affinity Capture-MS Homo sapiens
17 CHD4 1108
Affinity Capture-MS Homo sapiens
18 FAXC  
Affinity Capture-MS Homo sapiens
19 PRPS2 5634
Affinity Capture-MS Homo sapiens
20 YY1 7528
Proximity Label-MS Homo sapiens
21 RPA3 6119
Proximity Label-MS Homo sapiens
22 TRIM37  
Proximity Label-MS Homo sapiens
23 ZNF408  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 SMAD9  
Two-hybrid Homo sapiens
25 ZMYND8 23613
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 TCAF1 9747
Two-hybrid Homo sapiens
28 ZNF687  
Affinity Capture-MS Homo sapiens
29 SIRT6  
Affinity Capture-MS Homo sapiens
30 SLC7A6 9057
Affinity Capture-MS Homo sapiens
31 INTS3 65123
Affinity Capture-MS Homo sapiens
32 SCRIB 23513
Affinity Capture-MS Homo sapiens
33 P4HA3 283208
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 H2AFB2  
Affinity Capture-MS Homo sapiens
35 SLC31A1 1317
Affinity Capture-MS Homo sapiens
36 SSRP1 6749
Affinity Capture-MS Homo sapiens
37 INTS5 80789
Affinity Capture-MS Homo sapiens
38 BRD3 8019
Affinity Capture-MS Homo sapiens
39 RCOR1  
Affinity Capture-MS Homo sapiens
40 KDM5C  
Affinity Capture-MS Homo sapiens
41 PIPSL 266971
Affinity Capture-MS Homo sapiens
42 BRD4 23476
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 INTS6 26512
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ZNF592 is involved
No pathways found





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