Gene description for BRD4
Gene name	bromodomain containing 4
Gene symbol	BRD4
Other names/aliases	CAP HUNK1 HUNKI MCAP
Species	Homo sapiens
Database cross references - BRD4
ExoCarta	ExoCarta_23476
Vesiclepedia	VP_23476
Entrez Gene	23476
HGNC	13575
MIM	608749
UniProt	O60885
BRD4 identified in sEVs derived from the following tissue/cell type
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Hepatocellular carcinoma cells	26054723
Hepatocytes	26054723
Neuroblastoma cells	25944692

Gene ontology annotations for BRD4

Molecular Function     transcription cis-regulatory region binding GO:0000976 IDA     p53 binding GO:0002039 IDA     chromatin binding GO:0003682 IBA     chromatin binding GO:0003682 IDA     transcription coregulator activity GO:0003712 IMP     transcription coactivator activity GO:0003713 IMP     protein serine/threonine kinase activity GO:0004674 IBA     protein binding GO:0005515 IPI     RNA polymerase II CTD heptapeptide repeat kinase activity GO:0008353 IMP     enzyme binding GO:0019899 IPI     histone binding GO:0042393 IBA     lysine-acetylated histone binding GO:0070577 IDA     RNA polymerase II C-terminal domain binding GO:0099122 IDA     P-TEFb complex binding GO:0106140 IDA     histone reader activity GO:0140566 IDA Biological Process     chromatin remodeling GO:0006338 IBA     chromatin remodeling GO:0006338 IDA     regulation of transcription by RNA polymerase II GO:0006357 IBA     regulation of transcription by RNA polymerase II GO:0006357 IMP     DNA damage response GO:0006974 IEA     DNA damage response GO:0006974 IMP     positive regulation of G2/M transition of mitotic cell cycle GO:0010971 IMP     positive regulation of transcription elongation by RNA polymerase II GO:0032968 IDA     positive regulation of transcription elongation by RNA polymerase II GO:0032968 IMP     positive regulation of canonical NF-kappaB signal transduction GO:0043123 IDA     negative regulation by host of viral transcription GO:0043922 IDA     positive regulation of DNA-templated transcription GO:0045893 IMP     positive regulation of transcription by RNA polymerase II GO:0045944 IDA     regulation of inflammatory response GO:0050727 IDA     negative regulation of DNA damage checkpoint GO:2000002 IMP     positive regulation of T-helper 17 cell lineage commitment GO:2000330 ISS Subcellular Localization     chromatin GO:0000785 IBA     condensed nuclear chromosome GO:0000794 IDA     nucleus GO:0005634 IBA     nucleus GO:0005634 IDA     nucleoplasm GO:0005654 IDA     nucleoplasm GO:0005654 TAS     chromosome GO:0005694 IDA