Gene description for UBP1
Gene name upstream binding protein 1 (LBP-1a)
Gene symbol UBP1
Other names/aliases LBP-1B
LBP-1a
LBP1A
LBP1B
Species Homo sapiens
 Database cross references - UBP1
ExoCarta ExoCarta_7342
Vesiclepedia VP_7342
Entrez Gene 7342
HGNC 12507
MIM 609784
UniProt Q9NZI7  
 UBP1 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for UBP1
Molecular Function
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IDA
    DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 ISA
    DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 IBA
    DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 IDA
    protein binding GO:0005515 IPI
    sequence-specific double-stranded DNA binding GO:1990837 IDA
Biological Process
    angiogenesis GO:0001525 IEA
    regulation of transcription by RNA polymerase II GO:0006357 IBA
    regulation of transcription by RNA polymerase II GO:0006357 IDA
    negative regulation of viral transcription GO:0032897 IDA
    positive regulation of transcription by RNA polymerase II GO:0045944 IDA
Subcellular Localization
    chromatin GO:0000785 ISA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    cytosol GO:0005829 IDA
 Experiment description of studies that identified UBP1 in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for UBP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
2 MTHFD2 10797
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 FOXC1  
Affinity Capture-MS Homo sapiens
4 TFCP2 7024
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 FASN 2194
Positive Genetic Homo sapiens
6 GK3P  
Affinity Capture-MS Homo sapiens
7 PRKY  
Affinity Capture-MS Homo sapiens
8 FOXP3  
Affinity Capture-MS Homo sapiens
9 PRMT6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 FOXP1 27086
Affinity Capture-MS Homo sapiens
11 FOXD3  
Affinity Capture-MS Homo sapiens
12 XPO1 7514
Affinity Capture-MS Homo sapiens
13 USP5 8078
Co-fractionation Homo sapiens
14 CCT8L2  
Affinity Capture-MS Homo sapiens
15 WDR4 10785
Co-fractionation Homo sapiens
16 FOXA1  
Affinity Capture-MS Homo sapiens
17 JAK2 3717
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 TFAP4 7023
Affinity Capture-MS Homo sapiens
19 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
20 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
21 Clasp2  
Affinity Capture-MS Mus musculus
22 PTPN5  
Affinity Capture-MS Homo sapiens
23 FOXN1  
Affinity Capture-MS Homo sapiens
24 MORF4L1  
Two-hybrid Homo sapiens
25 EVL 51466
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 DPYSL4 10570
Affinity Capture-MS Homo sapiens
27 LAMTOR5 10542
Affinity Capture-MS Homo sapiens
28 HNRNPCL2 440563
Affinity Capture-MS Homo sapiens
29 TLE4  
Affinity Capture-MS Homo sapiens
30 RAB20 55647
Affinity Capture-MS Homo sapiens
31 ANKRD29  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 WWP2 11060
Affinity Capture-MS Homo sapiens
33 FAM19A3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 C12orf49  
Negative Genetic Homo sapiens
35 TRIM28 10155
Co-fractionation Homo sapiens
36 TFCP2L1  
Affinity Capture-MS Homo sapiens
37 MAGEB10  
Affinity Capture-MS Homo sapiens
38 STK35  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 GLYCTK  
Two-hybrid Homo sapiens
40 FOXC2  
Affinity Capture-MS Homo sapiens
41 GK  
Affinity Capture-MS Homo sapiens
42 SRF  
Affinity Capture-MS Homo sapiens
43 PARP1 142
Affinity Capture-MS Homo sapiens
44 ZNF512B  
Affinity Capture-MS Homo sapiens
45 TGM1 7051
Affinity Capture-MS Homo sapiens
46 DDX58 23586
Affinity Capture-RNA Homo sapiens
47 NR3C1 2908
Proximity Label-MS Homo sapiens
48 FOXE1  
Affinity Capture-MS Homo sapiens
49 HCFC2  
Affinity Capture-MS Homo sapiens
50 RPL35A 6165
Affinity Capture-MS Homo sapiens
51 BRD4 23476
Affinity Capture-MS Homo sapiens
52 HINT3 135114
Affinity Capture-MS Homo sapiens
53 ZNF184  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which UBP1 is involved
No pathways found





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