Experiment description of studies that identified KNOP1 in exosomes

1 Experiment ID 834 MISEV standards ✔ EM Biophysical techniques ✔ LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 835 MISEV standards ✔ EM Biophysical techniques ✔ CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for KNOP1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 GNL2 29889 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 2 UBE2H 7328 Affinity Capture-MS Homo sapiens 3 CENPB 1059 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 4 HIST1H2BC 8347 Cross-Linking-MS (XL-MS) Homo sapiens 5 ZNF668   Affinity Capture-MS Homo sapiens 6 H2AFJ 55766 Affinity Capture-MS Homo sapiens 7 RPL26L1 51121 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 8 RSL1D1 26156 Affinity Capture-MS Homo sapiens 9 ARHGEF19   Affinity Capture-MS Homo sapiens 10 COIL   Proximity Label-MS Homo sapiens 11 RPS3A 6189 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 12 PTMA 5757 Affinity Capture-MS Homo sapiens 13 KIAA0020 9933 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 14 TEX35   Cross-Linking-MS (XL-MS) Homo sapiens 15 HIST1H1D 3007 Affinity Capture-MS Homo sapiens 16 RPL13A 23521 Affinity Capture-MS Homo sapiens 17 RPL37A 6168 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 18 NOP56 10528 Proximity Label-MS Homo sapiens 19 NMNAT1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 20 RPS19 6223 Affinity Capture-MS Homo sapiens 21 RPL10 6134 Affinity Capture-MS Homo sapiens 22 HIST1H2BB 3018 Cross-Linking-MS (XL-MS) Homo sapiens 23 BRD2   Affinity Capture-MS Homo sapiens 24 RPL14 9045 Affinity Capture-MS Homo sapiens 25 HIST2H2BF 440689 Cross-Linking-MS (XL-MS) Homo sapiens 26 CENPA   Proximity Label-MS Homo sapiens 27 ILF2 3608 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 28 APEX1 328 Proximity Label-MS Homo sapiens 29 TCEB3 6924 Affinity Capture-MS Homo sapiens 30 DDX23 9416 Proximity Label-MS Homo sapiens 31 LOC102724334 102724334 Cross-Linking-MS (XL-MS) Homo sapiens 32 RPL10A 4736 Affinity Capture-MS Homo sapiens 33 SNRNP70 6625 Affinity Capture-MS Homo sapiens 34 PRR11   Affinity Capture-MS Homo sapiens 35 WHSC1 7468 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 36 LLPH   Affinity Capture-MS Homo sapiens 37 DDX24 57062 Affinity Capture-MS Homo sapiens 38 PRPF38B 55119 Affinity Capture-MS Homo sapiens 39 FBXW7   Affinity Capture-MS Homo sapiens 40 RPS10 6204 Affinity Capture-MS Homo sapiens 41 NPM1 4869 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 42 ANOS1 3730 Affinity Capture-MS Homo sapiens 43 FBL 2091 Affinity Capture-MS Homo sapiens Proximity Label-MS Homo sapiens 44 POLR1E   Proximity Label-MS Homo sapiens 45 RPS9 6203 Affinity Capture-MS Homo sapiens 46 RPF2 84154 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 47 PRKRA 8575 Affinity Capture-MS Homo sapiens 48 EXOSC4 54512 Affinity Capture-MS Homo sapiens 49 BRD4 23476 Affinity Capture-MS Homo sapiens 50 RRP8   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 51 ZNF346   Affinity Capture-MS Homo sapiens 52 MECP2 4204 Affinity Capture-MS Homo sapiens 53 MYCN   Affinity Capture-MS Homo sapiens 54 TACO1   Affinity Capture-MS Homo sapiens 55 MAK16   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 56 ARHGEF4   Affinity Capture-MS Homo sapiens 57 RPL19 6143 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 58 KIF14 9928 Affinity Capture-MS Homo sapiens 59 AURKA 6790 Affinity Capture-MS Homo sapiens 60 RPL27 6155 Affinity Capture-MS Homo sapiens 61 SRP9 6726 Affinity Capture-MS Homo sapiens 62 RPL30 6156 Affinity Capture-MS Homo sapiens 63 PIP4K2C 79837 Affinity Capture-MS Homo sapiens 64 HIST1H4A 8359 Affinity Capture-MS Homo sapiens 65 RPL4 6124 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 66 RBM28 55131 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 67 ZBTB47   Affinity Capture-MS Homo sapiens 68 RBM4B   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 69 STAU1 6780 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 70 RPL5 6125 Affinity Capture-MS Homo sapiens 71 SRSF6 6431 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 72 NOP2 4839 Affinity Capture-MS Homo sapiens 73 CBX3 11335 Proximity Label-MS Homo sapiens 74 ANAPC15   Affinity Capture-MS Homo sapiens 75 HIST1H2AM 8336 Affinity Capture-MS Homo sapiens 76 RPL18A 6142 Affinity Capture-MS Homo sapiens 77 ZCCHC17   Affinity Capture-MS Homo sapiens 78 OGT 8473 Reconstituted Complex Homo sapiens 79 RPL31 6160 Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 80 LRPAP1 4043 Affinity Capture-MS Homo sapiens 81 REXO4   Affinity Capture-MS Homo sapiens 82 SYNCRIP 10492 Affinity Capture-MS Homo sapiens 83 PARP1 142 Proximity Label-MS Homo sapiens 84 RBMX2   Affinity Capture-MS Homo sapiens 85 RPL36 25873 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 86 HIST1H2BG 8339 Proximity Label-MS Homo sapiens 87 UBTF 7343 Affinity Capture-MS Homo sapiens 88 CSNK1E 1454 Affinity Capture-MS Homo sapiens 89 HECTD1 25831 Affinity Capture-MS Homo sapiens 90 RPLP0 6175 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 91 MAGEB2 4113 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 92 MYBBP1A 10514 Affinity Capture-MS Homo sapiens 93 FGF13   Affinity Capture-MS Homo sapiens 94 RPSAP58 388524 Affinity Capture-MS Homo sapiens 95 C1orf189   Affinity Capture-MS Homo sapiens 96 CD3EAP   Proximity Label-MS Homo sapiens 97 WDR46   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 98 FGFBP1 9982 Affinity Capture-MS Homo sapiens 99 CENPN   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 100 HIST1H2BL 8340 Cross-Linking-MS (XL-MS) Homo sapiens 101 HIST1H3A 8350 Proximity Label-MS Homo sapiens 102 ABT1 29777 Affinity Capture-MS Homo sapiens 103 RPS2 6187 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 104 H1FNT   Affinity Capture-MS Homo sapiens 105 SRSF4 6429 Affinity Capture-MS Homo sapiens 106 IFI16 3428 Affinity Capture-MS Homo sapiens 107 SRSF1 6426 Affinity Capture-MS Homo sapiens 108 SHQ1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 109 RPS6 6194 Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 110 SRSF5 6430 Affinity Capture-MS Homo sapiens 111 RPL3 6122 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 112 EBNA1BP2 10969 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 113 RPL35 11224 Affinity Capture-MS Homo sapiens 114 SLTM 79811 Affinity Capture-MS Homo sapiens 115 AP2M1 1173 Two-hybrid Homo sapiens 116 ZNF512   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 117 PIP4K2A 5305 Affinity Capture-MS Homo sapiens 118 DKC1 1736 Affinity Capture-MS Homo sapiens 119 MYC   Affinity Capture-MS Homo sapiens 120 RPA3 6119 Proximity Label-MS Homo sapiens 121 NOL12 79159 Affinity Capture-MS Homo sapiens 122 DLST 1743 Affinity Capture-MS Homo sapiens 123 RPA4   Proximity Label-MS Homo sapiens 124 RPL22 6146 Affinity Capture-MS Homo sapiens 125 HIST1H1A 3024 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 126 PPAN 56342 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 127 DDRGK1 65992 Affinity Capture-MS Homo sapiens 128 ZC3HAV1 56829 Affinity Capture-MS Homo sapiens 129 ZFP62   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 130 LMNA 4000 Proximity Label-MS Homo sapiens 131 BRD3 8019 Affinity Capture-MS Homo sapiens 132 FTSJ3 117246 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 133 RPL11 6135 Affinity Capture-MS Homo sapiens 134 RPS16 6217 Affinity Capture-MS Homo sapiens 135 ZNF574   Affinity Capture-MS Homo sapiens 136 RPL13 6137 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 137 DHX15 1665 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 138 C8orf33 65265 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 139 RNF151   Affinity Capture-MS Homo sapiens 140 RBM19 9904 Affinity Capture-MS Homo sapiens 141 ILF3 3609 Affinity Capture-MS Homo sapiens 142 HIST1H2BK 85236 Cross-Linking-MS (XL-MS) Homo sapiens 143 SRRM1 10250 Affinity Capture-MS Homo sapiens 144 RRS1 23212 Affinity Capture-MS Homo sapiens 145 HERC2 8924 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 146 C9orf114   Affinity Capture-MS Homo sapiens 147 MNDA 4332 Affinity Capture-MS Homo sapiens 148 USP36   Affinity Capture-MS Homo sapiens 149 SRSF12   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 150 DGCR8   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 151 IFI6   Affinity Capture-MS Homo sapiens 152 HIST1H2BD 3017 Cross-Linking-MS (XL-MS) Homo sapiens 153 CENPU   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 154 MKI67   Affinity Capture-MS Homo sapiens 155 NIFK 84365 Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 156 C20orf197   Affinity Capture-MS Homo sapiens 157 KRR1 11103 Affinity Capture-MS Homo sapiens 158 NUP50 10762 Proximity Label-MS Homo sapiens 159 NEIL1   Affinity Capture-MS Homo sapiens 160 RPS24 6229 Proximity Label-MS Homo sapiens 161 ZNF106   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 162 RTCB 51493 Affinity Capture-MS Homo sapiens 163 RPL7A 6130 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Cross-Linking-MS (XL-MS) Homo sapiens 164 RPS8 6202 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 165 RPL8 6132 Affinity Capture-MS Homo sapiens 166 GLYR1 84656 Affinity Capture-MS Homo sapiens 167 PRPF4 9128 Affinity Capture-MS Homo sapiens 168 RPL23A 6147 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 169 DDX31   Affinity Capture-MS Homo sapiens 170 RPL36AL 6166 Affinity Capture-MS Homo sapiens 171 RBM34   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 172 UQCR11   Affinity Capture-MS Homo sapiens 173 HIST1H2AE 3012 Affinity Capture-MS Homo sapiens 174 RPL17 6139 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 175 Zbtb2 381990 Affinity Capture-MS Mus musculus View the network

Pathways in which KNOP1 is involved

No pathways found