Gene description for DLST
Gene name dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
Gene symbol DLST
Other names/aliases DLTS
Species Homo sapiens
 Database cross references - DLST
ExoCarta ExoCarta_1743
Vesiclepedia VP_1743
Entrez Gene 1743
HGNC 2911
MIM 126063
UniProt P36957  
 DLST identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Hepatocytes 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 25950383    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Prostate cancer cells 25844599    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
 Gene ontology annotations for DLST
Molecular Function
    dihydrolipoyllysine-residue succinyltransferase activity GO:0004149 IBA
    dihydrolipoyllysine-residue succinyltransferase activity GO:0004149 IMP
    dihydrolipoyllysine-residue succinyltransferase activity GO:0004149 ISS
    protein binding GO:0005515 IPI
    acyltransferase activity GO:0016746 IMP
Biological Process
    generation of precursor metabolites and energy GO:0006091 TAS
    tricarboxylic acid cycle GO:0006099 IBA
    tricarboxylic acid cycle GO:0006099 IEA
    tricarboxylic acid cycle GO:0006099 IMP
    2-oxoglutarate metabolic process GO:0006103 ISS
    succinyl-CoA metabolic process GO:0006104 ISS
    L-lysine catabolic process to acetyl-CoA via saccharopine GO:0033512 IEA
Subcellular Localization
    nucleus GO:0005634 HDA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IDA
    mitochondrial matrix GO:0005759 TAS
    cytosol GO:0005829 IDA
    membrane GO:0016020 HDA
    oxoglutarate dehydrogenase complex GO:0045252 IDA
    oxoadipate dehydrogenase complex GO:0160167 IDA
 Experiment description of studies that identified DLST in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
12
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
13
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
20
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
21
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
23
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
26
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
27
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
32
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
33
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
34
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
37
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
38
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for DLST
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SLC25A13 10165
Affinity Capture-MS Homo sapiens
2 RALYL 138046
Affinity Capture-MS Homo sapiens
3 LDHB 3945
Affinity Capture-MS Homo sapiens
4 ACOT9 23597
Affinity Capture-MS Homo sapiens
5 ACTC1 70
Affinity Capture-MS Homo sapiens
6 UBA1 7317
Affinity Capture-MS Homo sapiens
7 MTG2  
Proximity Label-MS Homo sapiens
8 C9orf78 51759
Affinity Capture-MS Homo sapiens
9 UBC 7316
Affinity Capture-MS Homo sapiens
10 PPIAL4A 653505
Affinity Capture-MS Homo sapiens
11 SOX2  
Affinity Capture-MS Homo sapiens
12 GFM2 84340
Proximity Label-MS Homo sapiens
13 CCDC90B  
Proximity Label-MS Homo sapiens
14 CKB 1152
Affinity Capture-MS Homo sapiens
15 TCEB3 6924
Co-fractionation Homo sapiens
16 DDX23 9416
Affinity Capture-MS Homo sapiens
17 MCU 90550
Proximity Label-MS Homo sapiens
18 DTX3  
Affinity Capture-MS Homo sapiens
19 DARS 1615
Affinity Capture-MS Homo sapiens
20 PMPCA 23203
Proximity Label-MS Homo sapiens
21 NDRG1 10397
Affinity Capture-MS Homo sapiens
22 HYOU1 10525
Affinity Capture-MS Homo sapiens
23 H2AFV 94239
Affinity Capture-MS Homo sapiens
24 ERC1 23085
Co-fractionation Homo sapiens
25 FBL 2091
Affinity Capture-MS Homo sapiens
26 CHMP2B 25978
Cross-Linking-MS (XL-MS) Homo sapiens
27 RHOA 387
Affinity Capture-MS Homo sapiens
28 MAGED2 10916
Affinity Capture-MS Homo sapiens
29 GSPT1 2935
Co-fractionation Homo sapiens
30 CHORDC1 26973
Affinity Capture-MS Homo sapiens
31 MECP2 4204
Affinity Capture-MS Homo sapiens
32 ARIH2 10425
Two-hybrid Homo sapiens
33 VWA8 23078
Proximity Label-MS Homo sapiens
34 MLEC 9761
Affinity Capture-MS Homo sapiens
35 MTA2 9219
Affinity Capture-MS Homo sapiens
36 UIMC1  
Affinity Capture-MS Homo sapiens
37 KIF14 9928
Affinity Capture-MS Homo sapiens
38 HPS5 11234
Affinity Capture-MS Homo sapiens
39 UBE4B 10277
Co-fractionation Homo sapiens
40 CAPZA1 829
Co-fractionation Homo sapiens
41 TOP2B 7155
Affinity Capture-MS Homo sapiens
42 TUFM 7284
Proximity Label-MS Homo sapiens
43 PABPC1 26986
Affinity Capture-MS Homo sapiens
44 TRIM21 6737
Affinity Capture-MS Homo sapiens
45 OGT 8473
Reconstituted Complex Homo sapiens
46 CCDC109B 55013
Proximity Label-MS Homo sapiens
47 GJB1 2705
Affinity Capture-MS Homo sapiens
48 DBT 1629
Co-fractionation Homo sapiens
49 MTRF1L  
Proximity Label-MS Homo sapiens
50 FLOT2 2319
Affinity Capture-MS Homo sapiens
51 SND1 27044
Affinity Capture-MS Homo sapiens
52 VDAC2 7417
Affinity Capture-MS Homo sapiens
53 SLC25A5 292
Affinity Capture-MS Homo sapiens
54 BRD7  
Affinity Capture-MS Homo sapiens
55 HIST1H2AD 3013
Affinity Capture-MS Homo sapiens
56 TMPO 7112
Affinity Capture-MS Homo sapiens
57 NOC3L 64318
Affinity Capture-MS Homo sapiens
58 MRPS12  
Proximity Label-MS Homo sapiens
59 MTIF2 4528
Proximity Label-MS Homo sapiens
60 LMNB1 4001
Affinity Capture-MS Homo sapiens
61 GRK5 2869
Affinity Capture-MS Homo sapiens
62 MYH14 79784
Affinity Capture-MS Homo sapiens
63 YWHAZ 7534
Affinity Capture-MS Homo sapiens
64 ATAD3C 219293
Affinity Capture-MS Homo sapiens
65 EPRS 2058
Affinity Capture-MS Homo sapiens
66 MYO1C 4641
Affinity Capture-MS Homo sapiens
67 YTHDC1  
Affinity Capture-MS Homo sapiens
68 ZNF512  
Affinity Capture-MS Homo sapiens
69 C12orf65  
Proximity Label-MS Homo sapiens
70 MTG1  
Proximity Label-MS Homo sapiens
71 RPA3 6119
Proximity Label-MS Homo sapiens
72 RAB11FIP2  
Affinity Capture-MS Homo sapiens
73 DLAT 1737
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
74 TPM4 7171
Affinity Capture-MS Homo sapiens
75 GNL3 26354
Affinity Capture-MS Homo sapiens
76 PRKDC 5591
Co-fractionation Homo sapiens
77 RELA 5970
Co-fractionation Homo sapiens
78 DNAJC28  
Proximity Label-MS Homo sapiens
79 FASN 2194
Affinity Capture-MS Homo sapiens
80 COPZ1 22818
Affinity Capture-MS Homo sapiens
81 AUH 549
Proximity Label-MS Homo sapiens
82 CHTOP  
Affinity Capture-MS Homo sapiens
83 PLEC 5339
Affinity Capture-MS Homo sapiens
84 PGK1 5230
Cross-Linking-MS (XL-MS) Homo sapiens
85 MTA1 9112
Affinity Capture-MS Homo sapiens
86 PCMT1 5110
Affinity Capture-MS Homo sapiens
87 BOLA2 552900
Affinity Capture-MS Homo sapiens
88 SSBP1 6742
Proximity Label-MS Homo sapiens
89 OAT 4942
Affinity Capture-MS Homo sapiens
90 ATAD3A 55210
Affinity Capture-MS Homo sapiens
91 SLC25A51  
Proximity Label-MS Homo sapiens
92 HNRNPA1L2 144983
Affinity Capture-MS Homo sapiens
93 CEBPB  
Co-fractionation Homo sapiens
94 CRNKL1 51340
Affinity Capture-MS Homo sapiens
95 RAB5C 5878
Affinity Capture-MS Homo sapiens
96 TAP1 6890
Affinity Capture-MS Homo sapiens
97 ANXA2 302
Affinity Capture-MS Homo sapiens
98 PSMC4 5704
Affinity Capture-MS Homo sapiens
99 LUC7L 55692
Affinity Capture-MS Homo sapiens
100 RANGAP1 5905
Affinity Capture-MS Homo sapiens
101 DYNC1LI2 1783
Co-fractionation Homo sapiens
102 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
103 GSTP1 2950
Affinity Capture-MS Homo sapiens
104 MCM3 4172
Affinity Capture-MS Homo sapiens
105 GART 2618
Affinity Capture-MS Homo sapiens
106 SIAH2 6478
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
107 USP13  
Affinity Capture-MS Homo sapiens
108 FMR1 2332
Affinity Capture-MS Homo sapiens
109 BTF3 689
Affinity Capture-MS Homo sapiens
110 PRPF38A 84950
Affinity Capture-MS Homo sapiens
111 DBN1 1627
Affinity Capture-MS Homo sapiens
112 NOP56 10528
Affinity Capture-MS Homo sapiens
113 CHCHD1  
Proximity Label-MS Homo sapiens
114 MRPL49 740
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
115 SAFB 6294
Affinity Capture-MS Homo sapiens
116 TNRC6C  
Affinity Capture-MS Homo sapiens
117 AKAP17A  
Affinity Capture-MS Homo sapiens
118 OGDH 4967
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
119 RBMXL2  
Affinity Capture-MS Homo sapiens
120 H1FX 8971
Affinity Capture-MS Homo sapiens
121 NUP93 9688
Affinity Capture-MS Homo sapiens
122 DNAJC7 7266
Proximity Label-MS Homo sapiens
123 PFN2 5217
Two-hybrid Homo sapiens
124 HSD17B4 3295
Affinity Capture-MS Homo sapiens
125 PMPCB 9512
Proximity Label-MS Homo sapiens
126 TACO1  
Proximity Label-MS Homo sapiens
127 FASTKD2  
Proximity Label-MS Homo sapiens
128 GAR1 54433
Affinity Capture-MS Homo sapiens
129 PRNP 5621
Affinity Capture-MS Homo sapiens
130 CCT2 10576
Affinity Capture-MS Homo sapiens
131 PFN1 5216
Affinity Capture-MS Homo sapiens
132 CALM2 805
Affinity Capture-MS Homo sapiens
133 C6orf203  
Proximity Label-MS Homo sapiens
134 DDX21 9188
Affinity Capture-MS Homo sapiens
135 ZBTB16  
Two-hybrid Homo sapiens
136 ACIN1 22985
Affinity Capture-MS Homo sapiens
137 NTPCR 84284
Affinity Capture-MS Homo sapiens
138 BPTF 2186
Affinity Capture-MS Homo sapiens
139 RAP1A 5906
Affinity Capture-MS Homo sapiens
140 HBA1 3039
Affinity Capture-MS Homo sapiens
141 OTC 5009
Proximity Label-MS Homo sapiens
142 RPN2 6185
Affinity Capture-MS Homo sapiens
143 CANX 821
Affinity Capture-MS Homo sapiens
144 RAB5A 5868
Affinity Capture-MS Homo sapiens
145 MRPS11  
Affinity Capture-MS Homo sapiens
146 MTIF3  
Proximity Label-MS Homo sapiens
147 RMND1 55005
Proximity Label-MS Homo sapiens
148 TJP1 7082
Affinity Capture-MS Homo sapiens
149 ATP5F1 515
Co-fractionation Homo sapiens
150 TUBB4B 10383
Two-hybrid Homo sapiens
151 EGFR 1956
Negative Genetic Homo sapiens
152 HSD17B10 3028
Affinity Capture-MS Homo sapiens
153 DUSP13  
Affinity Capture-MS Homo sapiens
154 TPM1 7168
Affinity Capture-MS Homo sapiens
155 PPP2R1A 5518
Affinity Capture-MS Homo sapiens
156 DYNC1LI1 51143
Co-fractionation Homo sapiens
157 ATP2A1 487
Affinity Capture-MS Homo sapiens
158 ACAD9 28976
Proximity Label-MS Homo sapiens
159 PGAM1 5223
Affinity Capture-MS Homo sapiens
160 MRPS17 51373
Affinity Capture-MS Homo sapiens
161 LMNA 4000
Affinity Capture-MS Homo sapiens
162 MCUR1 63933
Proximity Label-MS Homo sapiens
163 DSP 1832
Affinity Capture-MS Homo sapiens
164 CLPP 8192
Proximity Label-MS Homo sapiens
165 TAF6 6878
Co-fractionation Homo sapiens
166 CS 1431
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
167 C17orf80 55028
Proximity Label-MS Homo sapiens
168 ATXN3 4287
Affinity Capture-MS Homo sapiens
169 TP53 7157
Affinity Capture-MS Homo sapiens
170 PDCD6IP 10015
Affinity Capture-MS Homo sapiens
171 HDAC6 10013
Affinity Capture-MS Homo sapiens
172 KNOP1 400506
Affinity Capture-MS Homo sapiens
173 KDM4C  
Affinity Capture-MS Homo sapiens
174 CAPZA2 830
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
175 SQSTM1 8878
Affinity Capture-MS Homo sapiens
176 NOP10 55505
Affinity Capture-MS Homo sapiens
177 CDK1 983
Affinity Capture-MS Homo sapiens
178 RAD50 10111
Affinity Capture-MS Homo sapiens
179 SFSWAP  
Affinity Capture-MS Homo sapiens
180 FASTKD3  
Proximity Label-MS Homo sapiens
181 NLN 57486
Affinity Capture-MS Homo sapiens
182 GFM1 85476
Proximity Label-MS Homo sapiens
183 TAGLN2 8407
Affinity Capture-MS Homo sapiens
184 EEF1D 1936
Affinity Capture-MS Homo sapiens
185 TEFM  
Proximity Label-MS Homo sapiens
186 C1QBP 708
Proximity Label-MS Homo sapiens
187 ATP5C1 509
Affinity Capture-MS Homo sapiens
188 CKAP4 10970
Affinity Capture-MS Homo sapiens
189 AP3D1 8943
Affinity Capture-MS Homo sapiens
190 PRMT1 3276
Affinity Capture-MS Homo sapiens
191 CHMP2A 27243
Affinity Capture-MS Homo sapiens
192 SLIRP 81892
Proximity Label-MS Homo sapiens
193 DLG5 9231
Two-hybrid Homo sapiens
194 PPP3CA 5530
Co-fractionation Homo sapiens
195 NOP58 51602
Affinity Capture-MS Homo sapiens
196 RAB1A 5861
Affinity Capture-MS Homo sapiens
197 EEF1G 1937
Affinity Capture-MS Homo sapiens
198 CTPS2 56474
Co-fractionation Homo sapiens
199 YWHAE 7531
Affinity Capture-MS Homo sapiens
200 BOLA2B 654483
Affinity Capture-MS Homo sapiens
201 LRPPRC 10128
Proximity Label-MS Homo sapiens
202 CAPZB 832
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
203 INA 9118
Affinity Capture-MS Homo sapiens
204 TRIM28 10155
Affinity Capture-MS Homo sapiens
205 CRYZ 1429
Proximity Label-MS Homo sapiens
206 PAK4 10298
Two-hybrid Homo sapiens
207 HINT2 84681
Proximity Label-MS Homo sapiens
208 IQGAP1 8826
Co-fractionation Homo sapiens
209 MDC1  
Affinity Capture-MS Homo sapiens
210 HMGA2 8091
Affinity Capture-MS Homo sapiens
211 PDIA6 10130
Affinity Capture-MS Homo sapiens
212 MRPL39 54148
Co-fractionation Homo sapiens
213 NHP2 55651
Affinity Capture-MS Homo sapiens
214 THOC1 9984
Affinity Capture-MS Homo sapiens
215 MTERF3  
Proximity Label-MS Homo sapiens
216 RBM8A 9939
Affinity Capture-MS Homo sapiens
217 MDH2 4191
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
218 EIF2AK2 5610
Affinity Capture-MS Homo sapiens
219 DLD 1738
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
220 MYO18A 399687
Affinity Capture-MS Homo sapiens
221 SCFD1 23256
Two-hybrid Homo sapiens
222 RUSC2 9853
Two-hybrid Homo sapiens
223 FASTKD5  
Proximity Label-MS Homo sapiens
224 PRPH 5630
Affinity Capture-MS Homo sapiens
225 PARK2  
Affinity Capture-MS Homo sapiens
226 CHCHD3 54927
Affinity Capture-MS Homo sapiens
227 MARS 4141
Affinity Capture-MS Homo sapiens
228 DIABLO 56616
Proximity Label-MS Homo sapiens
229 CHMP4B 128866
Affinity Capture-MS Homo sapiens
230 RPA2 6118
Co-fractionation Homo sapiens
231 TPI1 7167
Affinity Capture-MS Homo sapiens
232 YLPM1 56252
Cross-Linking-MS (XL-MS) Homo sapiens
233 RPN1 6184
Affinity Capture-MS Homo sapiens
234 SMS 6611
Co-fractionation Homo sapiens
235 MRPL11 65003
Proximity Label-MS Homo sapiens
236 TMEM70  
Proximity Label-MS Homo sapiens
237 UCHL1 7345
Affinity Capture-MS Homo sapiens
238 MRPL2 51069
Affinity Capture-MS Homo sapiens
239 CKAP5 9793
Co-fractionation Homo sapiens
240 ACAT1 38
Affinity Capture-MS Homo sapiens
241 MRPL40 64976
Co-fractionation Homo sapiens
242 SLC25A12 8604
Proximity Label-MS Homo sapiens
243 ZHX1  
Two-hybrid Homo sapiens
244 BAG2 9532
Affinity Capture-MS Homo sapiens
245 SMARCA5 8467
Affinity Capture-MS Homo sapiens
246 EEF2 1938
Affinity Capture-MS Homo sapiens
247 LMNB2 84823
Affinity Capture-MS Homo sapiens
248 MRPS14  
Affinity Capture-MS Homo sapiens
249 NR3C1 2908
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
250 H1F0 3005
Affinity Capture-MS Homo sapiens
251 DHX30 22907
Proximity Label-MS Homo sapiens
252 CORO1C 23603
Affinity Capture-MS Homo sapiens
253 MYO1D 4642
Affinity Capture-MS Homo sapiens
254 PRPF19 27339
Affinity Capture-MS Homo sapiens
255 CAAP1  
Affinity Capture-MS Homo sapiens
256 YWHAQ 10971
Affinity Capture-MS Homo sapiens
257 HSDL2 84263
Affinity Capture-MS Homo sapiens
258 TOP1 7150
Affinity Capture-MS Homo sapiens
259 NHP2L1 4809
Affinity Capture-MS Homo sapiens
260 HP1BP3 50809
Affinity Capture-MS Homo sapiens
261 CGN  
Affinity Capture-MS Homo sapiens
262 MRPS36 92259
Affinity Capture-MS Homo sapiens
263 FLII 2314
Two-hybrid Homo sapiens
264 RANBP1 5902
Affinity Capture-MS Homo sapiens
265 CLPB 81570
Proximity Label-MS Homo sapiens
266 HSPA9 3313
Proximity Label-MS Homo sapiens
267 HLA-A 3105
Affinity Capture-MS Homo sapiens
268 METTL15  
Proximity Label-MS Homo sapiens
269 FLOT1 10211
Affinity Capture-MS Homo sapiens
270 NAA10 8260
Co-fractionation Homo sapiens
271 IMMT 10989
Affinity Capture-MS Homo sapiens
272 MTFMT  
Proximity Label-MS Homo sapiens
273 DNAJC4  
Proximity Label-MS Homo sapiens
274 TSFM 10102
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
275 SLC25A6 293
Affinity Capture-MS Homo sapiens
276 TECR 9524
Affinity Capture-MS Homo sapiens
277 SEC23IP 11196
Co-fractionation Homo sapiens
278 ILF2 3608
Affinity Capture-MS Homo sapiens
279 ICT1 3396
Proximity Label-MS Homo sapiens
280 LONP1 9361
Proximity Label-MS Homo sapiens
281 PDHA1 5160
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
282 TTBK1  
Affinity Capture-MS Homo sapiens
283 THRAP3 9967
Affinity Capture-MS Homo sapiens
284 HSPB1 3315
Affinity Capture-MS Homo sapiens
285 CLUH 23277
Co-fractionation Homo sapiens
286 PICALM 8301
Affinity Capture-MS Homo sapiens
287 RABL6 55684
Affinity Capture-MS Homo sapiens
288 CCT7 10574
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
289 TRAP1 10131
Affinity Capture-MS Homo sapiens
290 TBRG4 9238
Proximity Label-MS Homo sapiens
291 AARS2  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
292 HNRNPH3 3189
Affinity Capture-MS Homo sapiens
293 RAB7A 7879
Affinity Capture-MS Homo sapiens
294 RNPS1 10921
Affinity Capture-MS Homo sapiens
295 RPUSD3  
Proximity Label-MS Homo sapiens
296 CCDC80 151887
Affinity Capture-MS Homo sapiens
297 UBA6 55236
Co-fractionation Homo sapiens
298 PRDX3 10935
Affinity Capture-MS Homo sapiens
299 HIST1H2AE 3012
Affinity Capture-MS Homo sapiens
300 DDX28  
Proximity Label-MS Homo sapiens
301 UBE2H 7328
Affinity Capture-MS Homo sapiens
302 RIT1 6016
Negative Genetic Homo sapiens
303 RPL30 6156
Affinity Capture-MS Homo sapiens
304 KPNB1 3837
Affinity Capture-MS Homo sapiens
305 TRUB2  
Proximity Label-MS Homo sapiens
306 PAICS 10606
Affinity Capture-MS Homo sapiens
307 DHX8 1659
Affinity Capture-MS Homo sapiens
308 NGRN  
Proximity Label-MS Homo sapiens
309 ETFB 2109
Affinity Capture-MS Homo sapiens
310 PPIA 5478
Affinity Capture-MS Homo sapiens
311 CALM1 801
Affinity Capture-MS Homo sapiens
312 RPUSD4 84881
Proximity Label-MS Homo sapiens
313 DNAJC15  
Proximity Label-MS Homo sapiens
314 MTRF1  
Proximity Label-MS Homo sapiens
315 TAF5  
Affinity Capture-MS Homo sapiens
316 TOMM22 56993
Affinity Capture-MS Homo sapiens
317 KIAA1429 25962
Affinity Capture-MS Homo sapiens
318 TOP2A 7153
Affinity Capture-MS Homo sapiens
319 DYNC1H1 1778
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
320 TFAM 7019
Proximity Label-MS Homo sapiens
321 KIF5B 3799
Affinity Capture-MS Homo sapiens
322 IMPDH2 3615
Affinity Capture-MS Homo sapiens
323 C8orf82  
Proximity Label-MS Homo sapiens
324 NCOA5  
Affinity Capture-MS Homo sapiens
325 MRPL12 6182
Affinity Capture-MS Homo sapiens
326 CALM3 808
Affinity Capture-MS Homo sapiens
327 YWHAG 7532
Affinity Capture-MS Homo sapiens
328 Hdac6  
Affinity Capture-MS Mus musculus
329 MRPS26 64949
Proximity Label-MS Homo sapiens
330 SURF1  
Proximity Label-MS Homo sapiens
331 ATP5O 539
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
332 SERPINH1 871
Affinity Capture-MS Homo sapiens
333 MYO1B 4430
Affinity Capture-MS Homo sapiens
334 SRP68 6730
Affinity Capture-MS Homo sapiens
335 ASH2L 9070
Affinity Capture-MS Homo sapiens
336 H2AFY2 55506
Affinity Capture-MS Homo sapiens
337 SMARCB1 6598
Affinity Capture-MS Homo sapiens
338 CCDC86  
Two-hybrid Homo sapiens
339 RAB1B 81876
Affinity Capture-MS Homo sapiens
340 IMPDH1 3614
Co-fractionation Homo sapiens
341 STOML2 30968
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
342 E2F4  
Affinity Capture-MS Homo sapiens
343 PRPF6 24148
Affinity Capture-MS Homo sapiens
344 COX15 1355
Proximity Label-MS Homo sapiens
345 EMD 2010
Affinity Capture-MS Homo sapiens
346 SFXN3 81855
Affinity Capture-MS Homo sapiens
347 HSP90B1 7184
Affinity Capture-MS Homo sapiens
348 PSMC1 5700
Affinity Capture-MS Homo sapiens
349 HSCB 150274
Proximity Label-MS Homo sapiens
350 ACTL6A 86
Affinity Capture-MS Homo sapiens
351 EXD2  
Proximity Label-MS Homo sapiens
352 SF3B6 51639
Affinity Capture-MS Homo sapiens
353 PML 5371
Affinity Capture-MS Homo sapiens
354 MYH11 4629
Affinity Capture-MS Homo sapiens
355 DNAJC30  
Proximity Label-MS Homo sapiens
356 H2AFY 9555
Affinity Capture-MS Homo sapiens
357 ATP5B 506
Co-fractionation Homo sapiens
358 HIST1H2AB 8335
Affinity Capture-MS Homo sapiens
359 COX4I1 1327
Proximity Label-MS Homo sapiens
360 ENO3 2027
Affinity Capture-MS Homo sapiens
361 NUMA1 4926
Co-fractionation Homo sapiens
362 MRRF  
Proximity Label-MS Homo sapiens
363 FANCD2  
Affinity Capture-MS Homo sapiens
364 TAX1BP1 8887
Affinity Capture-MS Homo sapiens
365 DES 1674
Affinity Capture-MS Homo sapiens
366 EIF4G1 1981
Affinity Capture-MS Homo sapiens
367 PNN 5411
Affinity Capture-MS Homo sapiens
368 UQCRC2 7385
Affinity Capture-MS Homo sapiens
369 PLRG1 5356
Affinity Capture-MS Homo sapiens
370 MYL1 4632
Affinity Capture-MS Homo sapiens
371 NAA15 80155
Co-fractionation Homo sapiens
372 PDIA3 2923
Affinity Capture-MS Homo sapiens
373 NAP1L1 4673
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
374 PYCR2 29920
Affinity Capture-MS Homo sapiens
375 MRPL15 29088
Co-fractionation Homo sapiens
376 DKC1 1736
Affinity Capture-MS Homo sapiens
377 MYO6 4646
Affinity Capture-MS Homo sapiens
378 DYRK2 8445
Affinity Capture-MS Homo sapiens
379 CLTC 1213
Co-fractionation Homo sapiens
380 FSCN1 6624
Affinity Capture-MS Homo sapiens
381 MGEA5 10724
Co-fractionation Homo sapiens
382 GSN 2934
Affinity Capture-MS Homo sapiens
383 LBR 3930
Affinity Capture-MS Homo sapiens
384 RRBP1 6238
Affinity Capture-MS Homo sapiens
385 DNAJC19 131118
Proximity Label-MS Homo sapiens
386 PHRF1  
Affinity Capture-MS Homo sapiens
387 SAP18 10284
Affinity Capture-MS Homo sapiens
388 HBA2 3040
Affinity Capture-MS Homo sapiens
389 DNAJA3 9093
Proximity Label-MS Homo sapiens
390 PDHB 5162
Affinity Capture-MS Homo sapiens
391 SUCLA2 8803
Co-fractionation Homo sapiens
392 EIF4A3 9775
Affinity Capture-MS Homo sapiens
393 C21orf33  
Proximity Label-MS Homo sapiens
394 CWC15  
Affinity Capture-MS Homo sapiens
395 OGDHL  
Affinity Capture-MS Homo sapiens
396 SFXN1 94081
Affinity Capture-MS Homo sapiens
397 RBM4 5936
Affinity Capture-MS Homo sapiens
398 HECTD1 25831
Affinity Capture-MS Homo sapiens
399 C19orf52  
Proximity Label-MS Homo sapiens
400 GRSF1 2926
Proximity Label-MS Homo sapiens
401 XRCC6 2547
Affinity Capture-MS Homo sapiens
402 EIF5A 1984
Affinity Capture-MS Homo sapiens
403 METTL17  
Proximity Label-MS Homo sapiens
404 DSG2 1829
Affinity Capture-MS Homo sapiens
405 PARN  
Co-fractionation Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here