Gene description for PMPCA
Gene name peptidase (mitochondrial processing) alpha
Gene symbol PMPCA
Other names/aliases Alpha-MPP
INPP5E
P-55
Species Homo sapiens
 Database cross references - PMPCA
ExoCarta ExoCarta_23203
Vesiclepedia VP_23203
Entrez Gene 23203
HGNC 18667
MIM 613036
UniProt Q10713  
 PMPCA identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
 Gene ontology annotations for PMPCA
Molecular Function
    metalloendopeptidase activity GO:0004222 IEA
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
Biological Process
    protein processing involved in protein targeting to mitochondrion GO:0006627 IBA
    protein processing involved in protein targeting to mitochondrion GO:0006627 IDA
    protein processing involved in protein targeting to mitochondrion GO:0006627 IMP
    protein processing involved in protein targeting to mitochondrion GO:0006627 NAS
Subcellular Localization
    extracellular space GO:0005615 HDA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IDA
    mitochondrion GO:0005739 NAS
    mitochondrial inner membrane GO:0005743 IDA
    mitochondrial matrix GO:0005759 TAS
    mitochondrial processing peptidase complex GO:0017087 NAS
 Experiment description of studies that identified PMPCA in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
18
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
25
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for PMPCA
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MPST 4357
Co-fractionation Homo sapiens
2 OXCT1 5019
Proximity Label-MS Homo sapiens
3 SKIV2L 6499
Two-hybrid Homo sapiens
4 GUK1 2987
Co-fractionation Homo sapiens
5 MTG2  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
6 MRPL24  
Proximity Label-MS Homo sapiens
7 MRPL27 51264
Proximity Label-MS Homo sapiens
8 TXNDC12 51060
Co-fractionation Homo sapiens
9 MRPS18C  
Proximity Label-MS Homo sapiens
10 IARS2 55699
Proximity Label-MS Homo sapiens
11 CCS 9973
Co-fractionation Homo sapiens
12 NIT1 4817
Affinity Capture-MS Homo sapiens
13 PPM1K  
Affinity Capture-MS Homo sapiens
14 ETFA 2108
Proximity Label-MS Homo sapiens
15 FXN  
Co-fractionation Homo sapiens
16 POLRMT 5442
Proximity Label-MS Homo sapiens
17 DNAJC8 22826
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 IVD 3712
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
19 SLC30A9 10463
Proximity Label-MS Homo sapiens
20 BCS1L 617
Proximity Label-MS Homo sapiens
21 PREPL 9581
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
22 VWA8 23078
Proximity Label-MS Homo sapiens
23 MRPL47 57129
Proximity Label-MS Homo sapiens
24 KIF14 9928
Affinity Capture-MS Homo sapiens
25 ACP6 51205
Affinity Capture-MS Homo sapiens
26 RBMX 27316
Proximity Label-MS Homo sapiens
27 ACADVL 37
Proximity Label-MS Homo sapiens
28 NT5DC2 64943
Proximity Label-MS Homo sapiens
29 TUFM 7284
Proximity Label-MS Homo sapiens
30 KDELC2 143888
Co-fractionation Homo sapiens
31 OGT 8473
Reconstituted Complex Homo sapiens
32 MRPS6  
Proximity Label-MS Homo sapiens
33 THG1L 54974
Proximity Label-MS Homo sapiens
34 DBT 1629
Proximity Label-MS Homo sapiens
35 PAK7  
Affinity Capture-MS Homo sapiens
36 MTRF1L  
Proximity Label-MS Homo sapiens
37 ACN9  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
38 C17orf102  
Affinity Capture-MS Homo sapiens
39 MRPL41 64975
Proximity Label-MS Homo sapiens
40 ETHE1 23474
Co-fractionation Homo sapiens
41 MRPL14 64928
Proximity Label-MS Homo sapiens
42 WBSCR16  
Affinity Capture-MS Homo sapiens
43 HADHA 3030
Proximity Label-MS Homo sapiens
44 MTIF2 4528
Proximity Label-MS Homo sapiens
45 MCCC2 64087
Affinity Capture-MS Homo sapiens
46 SDHA 6389
Proximity Label-MS Homo sapiens
47 KRT86  
Affinity Capture-MS Homo sapiens
48 ANXA1 301
Co-fractionation Homo sapiens
49 MRPL16  
Proximity Label-MS Homo sapiens
50 CUL3 8452
Affinity Capture-MS Homo sapiens
51 DES 1674
Affinity Capture-MS Homo sapiens
52 GADD45GIP1  
Proximity Label-MS Homo sapiens
53 VARS2  
Proximity Label-MS Homo sapiens
54 HNRNPR 10236
Proximity Label-MS Homo sapiens
55 MTG1  
Proximity Label-MS Homo sapiens
56 PTPN7 5778
Affinity Capture-MS Homo sapiens
57 DLST 1743
Proximity Label-MS Homo sapiens
58 MRPL3  
Proximity Label-MS Homo sapiens
59 HIST1H1A 3024
Affinity Capture-MS Homo sapiens
60 TBCA 6902
Co-fractionation Homo sapiens
61 COX2 4513
Proximity Label-MS Homo sapiens
62 DLAT 1737
Proximity Label-MS Homo sapiens
63 PDP1 54704
Affinity Capture-MS Homo sapiens
64 MRPL18 29074
Proximity Label-MS Homo sapiens
65 HSPE1 3336
Proximity Label-MS Homo sapiens
66 GLS 2744
Proximity Label-MS Homo sapiens
67 ATP5J 522
Proximity Label-MS Homo sapiens
68 CLPX 10845
Proximity Label-MS Homo sapiens
69 MTPN 136319
Co-fractionation Homo sapiens
70 COQ5  
Proximity Label-MS Homo sapiens
71 SUCLG2 8801
Co-fractionation Homo sapiens
72 LARS2 23395
Proximity Label-MS Homo sapiens
73 LRPPRC 10128
Proximity Label-MS Homo sapiens
74 UQCC1 55245
Proximity Label-MS Homo sapiens
75 ATP5B 506
Proximity Label-MS Homo sapiens
76 NUDT19 390916
Proximity Label-MS Homo sapiens
77 SPATA20  
Affinity Capture-MS Homo sapiens
78 OAT 4942
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
79 MAGIX 79917
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 ATAD3A 55210
Proximity Label-MS Homo sapiens
81 NIPSNAP1 8508
Proximity Label-MS Homo sapiens
82 NME4 4833
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
83 HNRNPL 3191
Proximity Label-MS Homo sapiens
84 ACOT1 641371
Proximity Label-MS Homo sapiens
85 DEFB1  
Affinity Capture-MS Homo sapiens
86 FECH 2235
Proximity Label-MS Homo sapiens
87 DHRS4 10901
Affinity Capture-MS Homo sapiens
88 MRPS16  
Proximity Label-MS Homo sapiens
89 TXNIP 10628
Affinity Capture-MS Homo sapiens
90 MRPL55  
Proximity Label-MS Homo sapiens
91 POLG  
Proximity Label-MS Homo sapiens
92 MRPL28 10573
Proximity Label-MS Homo sapiens
93 NDUFS6  
Proximity Label-MS Homo sapiens
94 GSTP1 2950
Co-fractionation Homo sapiens
95 COX5A 9377
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
96 AFG3L2 10939
Proximity Label-MS Homo sapiens
97 MRPL48  
Proximity Label-MS Homo sapiens
98 ATP5J2-PTCD1  
Proximity Label-MS Homo sapiens
99 GTPBP10  
Proximity Label-MS Homo sapiens
100 RPA2 6118
Proximity Label-MS Homo sapiens
101 ALDH2 217
Proximity Label-MS Homo sapiens
102 CHCHD1  
Affinity Capture-MS Homo sapiens
103 MRPL50 54534
Proximity Label-MS Homo sapiens
104 GRPEL1 80273
Proximity Label-MS Homo sapiens
105 MRPL49 740
Proximity Label-MS Homo sapiens
106 C15orf48  
Affinity Capture-MS Homo sapiens
107 NDUFS2 4720
Proximity Label-MS Homo sapiens
108 GRHPR 9380
Co-fractionation Homo sapiens
109 MEI1  
Affinity Capture-MS Homo sapiens
110 OGDH 4967
Proximity Label-MS Homo sapiens
111 COQ9  
Affinity Capture-MS Homo sapiens
112 SUPV3L1 6832
Proximity Label-MS Homo sapiens
113 DIAPH2  
Co-fractionation Homo sapiens
114 MRPS23 51649
Proximity Label-MS Homo sapiens
115 NDUFA5 4698
Proximity Label-MS Homo sapiens
116 PRDX2 7001
Co-fractionation Homo sapiens
117 MALSU1  
Proximity Label-MS Homo sapiens
118 ERAL1  
Proximity Label-MS Homo sapiens
119 PHB 5245
Proximity Label-MS Homo sapiens
120 NDUFV3 4731
Proximity Label-MS Homo sapiens
121 MRPS7 51081
Proximity Label-MS Homo sapiens
122 PMPCB 9512
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
123 TACO1  
Proximity Label-MS Homo sapiens
124 FASTKD2  
Proximity Label-MS Homo sapiens
125 PDPR 55066
Proximity Label-MS Homo sapiens
126 NNT 23530
Proximity Label-MS Homo sapiens
127 C6orf203  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
128 MRPL45 84311
Proximity Label-MS Homo sapiens
129 ATPAF1  
Proximity Label-MS Homo sapiens
130 PDHX 8050
Proximity Label-MS Homo sapiens
131 POLDIP2 26073
Proximity Label-MS Homo sapiens
132 UQCRC1 7384
Co-fractionation Homo sapiens
133 RNMTL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
134 GMPS 8833
Co-fractionation Homo sapiens
135 ABCB7 22
Proximity Label-MS Homo sapiens
136 NDUFV1 4723
Proximity Label-MS Homo sapiens
137 CISD3 284106
Affinity Capture-MS Homo sapiens
138 MRPL44  
Proximity Label-MS Homo sapiens
139 IBA57  
Proximity Label-MS Homo sapiens
140 MRPS35 60488
Proximity Label-MS Homo sapiens
141 PPA1 5464
Co-fractionation Homo sapiens
142 RTN4IP1  
Proximity Label-MS Homo sapiens
143 MRPL9 65005
Proximity Label-MS Homo sapiens
144 ATP5F1 515
Proximity Label-MS Homo sapiens
145 HSD17B10 3028
Proximity Label-MS Homo sapiens
146 GHITM 27069
Affinity Capture-MS Homo sapiens
147 DHTKD1 55526
Proximity Label-MS Homo sapiens
148 NUDT8  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
149 HNRNPAB 3182
Proximity Label-MS Homo sapiens
150 SUGCT  
Affinity Capture-MS Homo sapiens
151 MRPS17 51373
Proximity Label-MS Homo sapiens
152 NDUFV2 4729
Proximity Label-MS Homo sapiens
153 HUWE1 10075
Affinity Capture-MS Homo sapiens
154 PPIF 10105
Proximity Label-MS Homo sapiens
155 CLPP 8192
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
156 CS 1431
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
157 C17orf80 55028
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
158 ALDH4A1 8659
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
159 HLTF  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
160 TRMT61B  
Proximity Label-MS Homo sapiens
161 FKBP4 2288
Co-fractionation Homo sapiens
162 COX8A  
Proximity Label-MS Homo sapiens
163 SHMT2 6472
Proximity Label-MS Homo sapiens
164 ME2 4200
Proximity Label-MS Homo sapiens
165 IDH2 3418
Co-fractionation Homo sapiens
166 GFM1 85476
Proximity Label-MS Homo sapiens
167 MINPP1 9562
Co-fractionation Homo sapiens
168 TEFM  
Proximity Label-MS Homo sapiens
169 ANXA5 308
Co-fractionation Homo sapiens
170 QRSL1  
Proximity Label-MS Homo sapiens
171 MRPS9 64965
Proximity Label-MS Homo sapiens
172 GLRX5 51218
Co-fractionation Homo sapiens
173 MRPS27 23107
Proximity Label-MS Homo sapiens
174 SLIRP 81892
Proximity Label-MS Homo sapiens
175 C6orf57  
Affinity Capture-MS Homo sapiens
176 NDUFS1 4719
Proximity Label-MS Homo sapiens
177 MRPL30  
Proximity Label-MS Homo sapiens
178 MRPL17  
Proximity Label-MS Homo sapiens
179 ANGEL2 90806
Proximity Label-MS Homo sapiens
180 LAP3 51056
Co-fractionation Homo sapiens
181 SUCLG1 8802
Co-fractionation Homo sapiens
182 PYCR1 5831
Proximity Label-MS Homo sapiens
183 GATB  
Proximity Label-MS Homo sapiens
184 CARS2 79587
Proximity Label-MS Homo sapiens
185 C7orf55  
Affinity Capture-MS Homo sapiens
186 ACAD9 28976
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
187 NDUFS3 4722
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
188 CRYZ 1429
Co-fractionation Homo sapiens
189 CHCHD2  
Affinity Capture-MS Homo sapiens
190 HINT2 84681
Proximity Label-MS Homo sapiens
191 PDK2 5164
Proximity Label-MS Homo sapiens
192 MRPL39 54148
Proximity Label-MS Homo sapiens
193 NDUFAF1  
Proximity Label-MS Homo sapiens
194 COQ10A  
Affinity Capture-MS Homo sapiens
195 MRPL4 51073
Proximity Label-MS Homo sapiens
196 ADCK4 79934
Affinity Capture-MS Homo sapiens
197 UQCC2  
Proximity Label-MS Homo sapiens
198 CGB2  
Affinity Capture-MS Homo sapiens
199 MTERF3  
Proximity Label-MS Homo sapiens
200 MDH2 4191
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
201 ALAS1  
Proximity Label-MS Homo sapiens
202 ATAD3B 83858
Proximity Label-MS Homo sapiens
203 MRPS25 64432
Proximity Label-MS Homo sapiens
204 ATP5A1 498
Affinity Capture-MS Homo sapiens
205 THEM4  
Proximity Label-MS Homo sapiens
206 FASTKD5  
Proximity Label-MS Homo sapiens
207 PARK2  
Affinity Capture-MS Homo sapiens
208 PAM16  
Proximity Label-MS Homo sapiens
209 DIABLO 56616
Proximity Label-MS Homo sapiens
210 NDUFAF5  
Proximity Label-MS Homo sapiens
211 TPI1 7167
Co-fractionation Homo sapiens
212 COA7  
Co-fractionation Homo sapiens
213 CTSB 1508
Co-fractionation Homo sapiens
214 CREG1 8804
Co-fractionation Homo sapiens
215 MRPL2 51069
Proximity Label-MS Homo sapiens
216 HNRNPDL 9987
Proximity Label-MS Homo sapiens
217 ACAT1 38
Proximity Label-MS Homo sapiens
218 MRPL40 64976
Proximity Label-MS Homo sapiens
219 SLC25A12 8604
Proximity Label-MS Homo sapiens
220 METTL14  
Affinity Capture-MS Homo sapiens
221 TRMT10C 54931
Proximity Label-MS Homo sapiens
222 PNPT1 87178
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
223 SPR 6697
Co-fractionation Homo sapiens
224 MRPL37 51253
Proximity Label-MS Homo sapiens
225 MRPS14  
Proximity Label-MS Homo sapiens
226 CA5A  
Affinity Capture-MS Homo sapiens
227 LYRM1  
Affinity Capture-MS Homo sapiens
228 DHX30 22907
Proximity Label-MS Homo sapiens
229 BOLA1 51027
Affinity Capture-MS Homo sapiens
230 MRPS28  
Proximity Label-MS Homo sapiens
231 CECR5 27440
Affinity Capture-MS Homo sapiens
232 MRPL19 9801
Proximity Label-MS Homo sapiens
233 LACTB2 51110
Co-fractionation Homo sapiens
234 HSDL2 84263
Proximity Label-MS Homo sapiens
235 PABPN1L  
Affinity Capture-MS Homo sapiens
236 MRPS36 92259
Proximity Label-MS Homo sapiens
237 HSPD1 3329
Proximity Label-MS Homo sapiens
238 MRPL38  
Proximity Label-MS Homo sapiens
239 METTL15  
Proximity Label-MS Homo sapiens
240 APOA1BP 128240
Co-fractionation Homo sapiens
241 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
242 PHB2 11331
Proximity Label-MS Homo sapiens
243 TSFM 10102
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
244 PDK3 5165
Proximity Label-MS Homo sapiens
245 NDUFAF2  
Proximity Label-MS Homo sapiens
246 COQ6 51004
Affinity Capture-MS Homo sapiens
247 ICT1 3396
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
248 LONP1 9361
Proximity Label-MS Homo sapiens
249 SPINK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
250 MRPL53  
Proximity Label-MS Homo sapiens
251 PDHA1 5160
Proximity Label-MS Homo sapiens
252 C17orf89  
Affinity Capture-MS Homo sapiens
253 NDUFA12 55967
Proximity Label-MS Homo sapiens
254 CLUH 23277
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
255 MRPS10 55173
Proximity Label-MS Homo sapiens
256 GUF1  
Proximity Label-MS Homo sapiens
257 NDUFS8 4728
Proximity Label-MS Homo sapiens
258 MRPS18B 28973
Proximity Label-MS Homo sapiens
259 NDUFA2 4695
Proximity Label-MS Homo sapiens
260 AARS2  
Proximity Label-MS Homo sapiens
261 PRDX6 9588
Co-fractionation Homo sapiens
262 MGME1  
Proximity Label-MS Homo sapiens
263 SERBP1 26135
Affinity Capture-MS Homo sapiens
264 MRPS22 56945
Proximity Label-MS Homo sapiens
265 FLAD1 80308
Proximity Label-MS Homo sapiens
266 TFAM 7019
Proximity Label-MS Homo sapiens
267 TIMM44 10469
Proximity Label-MS Homo sapiens
268 RIT1 6016
Negative Genetic Homo sapiens
269 C7orf55-LUC7L2  
Proximity Label-MS Homo sapiens
270 ATPIF1 93974
Proximity Label-MS Homo sapiens
271 ADCK3  
Affinity Capture-MS Homo sapiens
272 SPRYD4 283377
Affinity Capture-MS Homo sapiens
273 TRUB2  
Proximity Label-MS Homo sapiens
274 PTPN9 5780
Affinity Capture-MS Homo sapiens
275 MRPL10 124995
Proximity Label-MS Homo sapiens
276 ETFB 2109
Proximity Label-MS Homo sapiens
277 C4orf26  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
278 MRPL52  
Proximity Label-MS Homo sapiens
279 KRTAP13-2  
Affinity Capture-MS Homo sapiens
280 MTRF1  
Proximity Label-MS Homo sapiens
281 HADH 3033
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
282 ATP5D 513
Proximity Label-MS Homo sapiens
283 MARK2 2011
Affinity Capture-MS Homo sapiens
284 MRPL20 55052
Proximity Label-MS Homo sapiens
285 CCDC69 26112
Affinity Capture-MS Homo sapiens
286 PRDX3 10935
Proximity Label-MS Homo sapiens
287 NDUFA7 4701
Proximity Label-MS Homo sapiens
288 MRPL23 6150
Proximity Label-MS Homo sapiens
289 MRPS5 64969
Proximity Label-MS Homo sapiens
290 MRPS24 64951
Proximity Label-MS Homo sapiens
291 MRPL12 6182
Proximity Label-MS Homo sapiens
292 C21orf33  
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
293 MRPS26 64949
Proximity Label-MS Homo sapiens
294 ATP5O 539
Proximity Label-MS Homo sapiens
295 ATP5H 10476
Proximity Label-MS Homo sapiens
296 GSTO1 9446
Co-fractionation Homo sapiens
297 NDUFA6  
Proximity Label-MS Homo sapiens
298 DAP3 7818
Proximity Label-MS Homo sapiens
299 STOML2 30968
Proximity Label-MS Homo sapiens
300 MRPS30 10884
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
301 PDK1 5163
Proximity Label-MS Homo sapiens
302 MRPL32 64983
Proximity Label-MS Homo sapiens
303 NDUFS4 4724
Proximity Label-MS Homo sapiens
304 MRPS34 65993
Proximity Label-MS Homo sapiens
305 ACOT2 10965
Proximity Label-MS Homo sapiens
306 CDRT15  
Affinity Capture-MS Homo sapiens
307 PTCD3 55037
Proximity Label-MS Homo sapiens
308 MMAB 326625
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
309 LYRM4 57128
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
310 MRPL22  
Proximity Label-MS Homo sapiens
311 CLIC4 25932
Co-fractionation Homo sapiens
312 NDUFAF3 25915
Proximity Label-MS Homo sapiens
313 MRPS33  
Proximity Label-MS Homo sapiens
314 COX4I1 1327
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
315 OXA1L  
Proximity Label-MS Homo sapiens
316 PDE12 201626
Proximity Label-MS Homo sapiens
317 COPS2 9318
Co-fractionation Homo sapiens
318 MRPL21 219927
Proximity Label-MS Homo sapiens
319 MRRF  
Proximity Label-MS Homo sapiens
320 NDUFA9 4704
Proximity Label-MS Homo sapiens
321 LETM1 3954
Proximity Label-MS Homo sapiens
322 GCDH 2639
Proximity Label-MS Homo sapiens
323 C2orf47  
Affinity Capture-MS Homo sapiens
324 NFS1 9054
Proximity Label-MS Homo sapiens
325 NPPA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
326 ELAC2 60528
Proximity Label-MS Homo sapiens
327 GAA 2548
Co-fractionation Homo sapiens
328 PYCR2 29920
Proximity Label-MS Homo sapiens
329 ECHS1 1892
Proximity Label-MS Homo sapiens
330 MRPL15 29088
Proximity Label-MS Homo sapiens
331 ECI2 10455
Proximity Label-MS Homo sapiens
332 MRPL1  
Proximity Label-MS Homo sapiens
333 APOOL 139322
Affinity Capture-MS Homo sapiens
334 KRAS 3845
Negative Genetic Homo sapiens
335 NUBPL 80224
Proximity Label-MS Homo sapiens
336 C10orf2 56652
Proximity Label-MS Homo sapiens
337 AK4 205
Proximity Label-MS Homo sapiens
338 MRPL42  
Proximity Label-MS Homo sapiens
339 GLUD1 2746
Proximity Label-MS Homo sapiens
340 MRPS2 51116
Proximity Label-MS Homo sapiens
341 PNPLA8 50640
Proximity Label-MS Homo sapiens
342 ABHD10 55347
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
343 MRPS31  
Proximity Label-MS Homo sapiens
344 MRPL43 84545
Proximity Label-MS Homo sapiens
345 GATC  
Proximity Label-MS Homo sapiens
346 COQ7  
Affinity Capture-MS Homo sapiens
347 NDUFS7 374291
Proximity Label-MS Homo sapiens
348 PDHB 5162
Proximity Label-MS Homo sapiens
349 SUCLA2 8803
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
350 RPUSD2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
351 GARS 2617
Proximity Label-MS Homo sapiens
352 TXNRD2 10587
Co-fractionation Homo sapiens
353 MRPL13  
Proximity Label-MS Homo sapiens
354 MRPL46  
Proximity Label-MS Homo sapiens
355 GRSF1 2926
Proximity Label-MS Homo sapiens
356 NDUFAF4 29078
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
357 C9orf72  
Affinity Capture-MS Homo sapiens
358 METTL17  
Proximity Label-MS Homo sapiens
359 MRPS18A  
Proximity Label-MS Homo sapiens
360 ECSIT 51295
Proximity Label-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here