Gene description for APOOL
Gene name apolipoprotein O-like
Gene symbol APOOL
Other names/aliases CXorf33
FAM121A
UNQ8193
Species Homo sapiens
 Database cross references - APOOL
ExoCarta ExoCarta_139322
Vesiclepedia VP_139322
Entrez Gene 139322
HGNC 24009
UniProt Q6UXV4  
 APOOL identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for APOOL
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    inner mitochondrial membrane organization GO:0007007 IC
    cristae formation GO:0042407 IBA
    cristae formation GO:0042407 NAS
Subcellular Localization
    SAM complex GO:0001401 HDA
    extracellular region GO:0005576 TAS
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrial inner membrane GO:0005743 NAS
    platelet alpha granule lumen GO:0031093 TAS
    mitochondrial crista junction GO:0044284 NAS
    MICOS complex GO:0061617 HDA
    MICOS complex GO:0061617 IBA
    MICOS complex GO:0061617 IDA
    MICOS complex GO:0061617 NAS
    MIB complex GO:0140275 HDA
 Experiment description of studies that identified APOOL in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for APOOL
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ATG16L1 55054
Affinity Capture-MS Homo sapiens
2 MAGEA8  
Affinity Capture-MS Homo sapiens
3 SLC39A12  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 AFG3L2 10939
Affinity Capture-MS Homo sapiens
5 IMMT 10989
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 MECP2 4204
Affinity Capture-MS Homo sapiens
7 C15orf48  
Affinity Capture-MS Homo sapiens
8 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
9 PHB2 11331
Proximity Label-MS Homo sapiens
10 SLC15A1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 DNAJC11 55735
Affinity Capture-MS Homo sapiens
12 STARD7 56910
Affinity Capture-MS Homo sapiens
13 SLC25A12 8604
Proximity Label-MS Homo sapiens
14 TRAK1 22906
Affinity Capture-MS Homo sapiens
15 AIFM1 9131
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 DDAH1 23576
Affinity Capture-MS Homo sapiens
17 SLC39A9 55334
Affinity Capture-MS Homo sapiens
18 ATP5I 521
Affinity Capture-MS Homo sapiens
19 BAZ1B 9031
Affinity Capture-MS Homo sapiens
20 CMTM8  
Affinity Capture-MS Homo sapiens
21 MTX1 4580
Affinity Capture-MS Homo sapiens
22 STOML2 30968
Affinity Capture-MS Homo sapiens
23 APOO 79135
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 ATP5H 10476
Affinity Capture-MS Homo sapiens
25 RHOT1 55288
Affinity Capture-MS Homo sapiens
26 UQCRB 7381
Affinity Capture-MS Homo sapiens
27 MTCH2 23788
Affinity Capture-MS Homo sapiens
28 RBMXL1  
Affinity Capture-MS Homo sapiens
29 SLC1A5 6510
Affinity Capture-MS Homo sapiens
30 SAMM50 25813
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 CLEC12B  
Affinity Capture-MS Homo sapiens
32 NDUFA12 55967
Affinity Capture-MS Homo sapiens
33 AQP3  
Affinity Capture-MS Homo sapiens
34 CHCHD3 54927
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 COASY 80347
Affinity Capture-MS Homo sapiens
36 DUSP6 1848
Affinity Capture-MS Homo sapiens
37 SFXN1 94081
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 ATP5O 539
Affinity Capture-MS Homo sapiens
39 MTX2 10651
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 DIABLO 56616
Proximity Label-MS Homo sapiens
41 SLC18A2  
Affinity Capture-MS Homo sapiens
42 C9orf89 84270
Affinity Capture-MS Homo sapiens
43 YME1L1 10730
Affinity Capture-MS Homo sapiens
44 NRD1 4898
Affinity Capture-MS Homo sapiens
45 MTX3  
Affinity Capture-MS Homo sapiens
46 APOOL 139322
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 COX6C 1345
Affinity Capture-MS Homo sapiens
48 PMPCA 23203
Affinity Capture-MS Homo sapiens
49 SLC22A2 6582
Affinity Capture-MS Homo sapiens
50 SLC25A51  
Proximity Label-MS Homo sapiens
51 C19orf70  
Affinity Capture-MS Homo sapiens
52 CHCHD2  
Affinity Capture-MS Homo sapiens
53 ECH1 1891
Affinity Capture-MS Homo sapiens
54 GLMP 112770
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 RNF2  
Affinity Capture-MS Homo sapiens
56 CHCHD6 84303
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 SLC1A1 6505
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 SLC22A4 6583
Affinity Capture-MS Homo sapiens
59 ATP5E 514
Affinity Capture-MS Homo sapiens
60 NDUFB11 54539
Affinity Capture-MS Homo sapiens
61 TIMM44 10469
Affinity Capture-MS Homo sapiens
62 RMDN3 55177
Affinity Capture-MS Homo sapiens
63 COX4I1 1327
Proximity Label-MS Homo sapiens
View the network image/svg+xml



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