Gene description for NDUFB11
Gene name NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
Gene symbol NDUFB11
Other names/aliases CI-ESSS
ESSS
NP17.3
Np15
P17.3
Species Homo sapiens
 Database cross references - NDUFB11
ExoCarta ExoCarta_54539
Vesiclepedia VP_54539
Entrez Gene 54539
HGNC 20372
MIM 300403
UniProt Q9NX14  
 NDUFB11 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for NDUFB11
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    aerobic respiration GO:0009060 NAS
    mitochondrial respiratory chain complex I assembly GO:0032981 IMP
    proton motive force-driven mitochondrial ATP synthesis GO:0042776 NAS
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrial inner membrane GO:0005743 IDA
    mitochondrial inner membrane GO:0005743 TAS
    respiratory chain complex I GO:0045271 IBA
    respiratory chain complex I GO:0045271 IDA
 Experiment description of studies that identified NDUFB11 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for NDUFB11
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SUCO  
Affinity Capture-MS Homo sapiens
2 Mtx2  
Affinity Capture-MS Mus musculus
3 NDUFS1 4719
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 TPP1 1200
Co-fractionation Homo sapiens
5 RPA2 6118
Proximity Label-MS Homo sapiens
6 NDUFB5 4711
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 SURF4 6836
Co-fractionation Homo sapiens
8 UQCRB 7381
Co-fractionation Homo sapiens
9 NDUFS7 374291
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 EIF4A1 1973
Co-fractionation Homo sapiens
11 NDUFA4 4697
Affinity Capture-MS Homo sapiens
12 NDUFS2 4720
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 KIAA1429 25962
Affinity Capture-MS Homo sapiens
14 NDUFB9 4715
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
15 NDUFS3 4722
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 NDUFB8 4714
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 SDHB 6390
Co-fractionation Homo sapiens
18 NDUFA7 4701
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 TIMMDC1  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
20 NDUFAB1 4706
Affinity Capture-MS Homo sapiens
21 NDUFA5 4698
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
22 ABCD3 5825
Co-fractionation Homo sapiens
23 LAMTOR3 8649
Co-fractionation Homo sapiens
24 PPBP 5473
Two-hybrid Homo sapiens
25 TXNDC5 81567
Co-fractionation Homo sapiens
26 NDUFAF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 NDUFV3 4731
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 CYSTM1 84418
Co-fractionation Homo sapiens
29 NDUFA11 126328
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 NDUFA6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 VAPA 9218
Affinity Capture-MS Homo sapiens
32 NDUFS5 4725
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 NDUFA1 4694
Affinity Capture-MS Homo sapiens
34 NDUFB10 4716
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 NDUFB1 4707
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 CLDN7 1366
Two-hybrid Homo sapiens
37 NDUFS4 4724
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 NDUFB7 4713
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 TMX1 81542
Co-fractionation Homo sapiens
40 ND2 4536
Affinity Capture-MS Homo sapiens
41 TMEM55B 90809
Affinity Capture-MS Homo sapiens
42 BAG6 7917
Two-hybrid Homo sapiens
43 Atp5a1 11946
Affinity Capture-MS Mus musculus
44 PMAIP1  
Affinity Capture-MS Homo sapiens
45 ND1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 NDUFA2 4695
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 GJB1 2705
Two-hybrid Homo sapiens
48 DNAJC30  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 ZYG11B  
Affinity Capture-MS Homo sapiens
50 NDUFAF3 25915
Co-fractionation Homo sapiens
51 ATP5B 506
Co-fractionation Homo sapiens
52 TMEM185A  
Affinity Capture-MS Homo sapiens
53 NDUFV1 4723
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 Rab5c 19345
Affinity Capture-MS Mus musculus
55 APLNR  
Affinity Capture-MS Homo sapiens
56 SLC25A12 8604
Proximity Label-MS Homo sapiens
57 VAPB 9217
Affinity Capture-MS Homo sapiens
58 MCCC2 64087
Co-fractionation Homo sapiens
59 NDUFA13 51079
Affinity Capture-MS Homo sapiens
60 NDUFA9 4704
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 ND5 4540
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 GPR101  
Two-hybrid Homo sapiens
63 GPR152  
Two-hybrid Homo sapiens
64 GPR42  
Two-hybrid Homo sapiens
65 NDUFB3 4709
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 APOOL 139322
Affinity Capture-MS Homo sapiens
67 HIBADH 11112
Two-hybrid Homo sapiens
68 P4HB 5034
Co-fractionation Homo sapiens
69 NDUFB6 4712
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 ACAD9 28976
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 ABCB10 23456
Co-fractionation Homo sapiens
72 NDUFA3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
73 NDUFA10 4705
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
74 MARS2 92935
Affinity Capture-MS Homo sapiens
75 FATE1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
76 NDUFV2 4729
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
77 NDUFC2 4718
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
78 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
79 NDUFA12 55967
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 EBP  
Two-hybrid Homo sapiens
81 Sass6  
Affinity Capture-MS Mus musculus
82 SFXN1 94081
Proximity Label-MS Homo sapiens
83 NDUFS8 4728
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 TMEM126B 55863
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
85 SLC25A51  
Proximity Label-MS Homo sapiens
86 Tnpo1 238799
Affinity Capture-MS Mus musculus
87 RAB5C 5878
Affinity Capture-MS Homo sapiens
88 ND4 4538
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
89 NDUFS6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
90 COX4I1 1327
Proximity Label-MS Homo sapiens
91 ECSIT 51295
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
92 NDUFB4 4710
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
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