Gene description for VAPA
Gene name VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
Gene symbol VAPA
Other names/aliases VAP-33
VAP-A
VAP33
hVAP-33
Species Homo sapiens
 Database cross references - VAPA
ExoCarta ExoCarta_9218
Vesiclepedia VP_9218
Entrez Gene 9218
HGNC 12648
MIM 605703
UniProt Q9P0L0  
 VAPA identified in sEVs derived from the following tissue/cell type
Bladder cancer cells 20224111    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Pluripotent stem cells 34108659    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for VAPA
Molecular Function
    protein binding GO:0005515 IPI
    microtubule binding GO:0008017 IMP
    protein domain specific binding GO:0019904 IPI
    FFAT motif binding GO:0033149 IDA
    FFAT motif binding GO:0033149 IMP
    protein homodimerization activity GO:0042803 IDA
    protein-membrane adaptor activity GO:0043495 IBA
    cadherin binding GO:0045296 HDA
    protein heterodimerization activity GO:0046982 IPI
Biological Process
    sphingomyelin biosynthetic process GO:0006686 IMP
    endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888 IMP
    endoplasmic reticulum organization GO:0007029 IMP
    phospholipid transport GO:0015914 IDA
    sterol transport GO:0015918 IDA
    viral release from host cell GO:0019076 IDA
    cholesterol transport GO:0030301 IDA
    neuron projection development GO:0031175 IBA
    neuron projection development GO:0031175 IMP
    protein folding in endoplasmic reticulum GO:0034975 IMP
    ceramide transport GO:0035627 IMP
    positive regulation of canonical NF-kappaB signal transduction GO:0043123 HMP
    negative regulation by host of viral genome replication GO:0044828 IDA
    positive regulation by host of viral genome replication GO:0044829 IDA
    membrane fusion GO:0061025 TAS
    endoplasmic reticulum-plasma membrane tethering GO:0061817 IDA
    protein localization to endoplasmic reticulum GO:0070972 IMP
    COPII-coated vesicle budding GO:0090114 IMP
Subcellular Localization
    Golgi membrane GO:0000139 IDA
    endoplasmic reticulum GO:0005783 HDA
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum membrane GO:0005789 IBA
    endoplasmic reticulum membrane GO:0005789 IDA
    endoplasmic reticulum membrane GO:0005789 TAS
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 TAS
    bicellular tight junction GO:0005923 IDA
    microtubule cytoskeleton GO:0015630 IEA
    nuclear membrane GO:0031965 IEA
    vesicle GO:0031982 IDA
    azurophil granule membrane GO:0035577 TAS
    perinuclear region of cytoplasm GO:0048471 IDA
    endoplasmic reticulum exit site GO:0070971 IDA
 Experiment description of studies that identified VAPA in sEVs
1
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
2
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
8
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 234
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
20
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
21
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
22
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
23
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
34
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
37
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
38
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
39
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
40
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
41
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
42
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
43
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for VAPA
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PLEKHA3  
Affinity Capture-MS Homo sapiens
2 AHCTF1 25909
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 GJD3  
Proximity Label-MS Homo sapiens
4 ISG15 9636
Affinity Capture-MS Homo sapiens
5 KRTCAP2 200185
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 SRPRB 58477
Affinity Capture-MS Homo sapiens
7 NFATC1 4772
Affinity Capture-MS Homo sapiens
8 SLC25A1 6576
Affinity Capture-MS Homo sapiens
9 VPS13C 54832
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 UQCRFS1 7386
Affinity Capture-MS Homo sapiens
11 MCU 90550
Affinity Capture-MS Homo sapiens
12 STX1A 6804
Affinity Capture-Western Homo sapiens
13 LPGAT1 9926
Affinity Capture-MS Homo sapiens
14 OSBPL9 114883
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 TRIOBP 11078
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 METAP2 10988
Affinity Capture-MS Homo sapiens
17 RAI14 26064
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 ALPK2  
Affinity Capture-MS Homo sapiens
19 ABCD3 5825
Affinity Capture-MS Homo sapiens
20 MARCH5  
Proximity Label-MS Homo sapiens
21 HELLS 3070
Affinity Capture-MS Homo sapiens
22 USP33  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 FAF1 11124
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
24 SLC25A46 91137
Proximity Label-MS Homo sapiens
25 BCS1L 617
Co-fractionation Homo sapiens
26 GPX8 493869
Affinity Capture-MS Homo sapiens
27 CCNB2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 KIF14 9928
Affinity Capture-MS Homo sapiens
29 CAMLG 819
Affinity Capture-MS Homo sapiens
30 KLF16  
Affinity Capture-MS Homo sapiens
31 GOLIM4 27333
Affinity Capture-MS Homo sapiens
32 BAG5 9529
Affinity Capture-MS Homo sapiens
33 OPRD1  
Affinity Capture-Western Homo sapiens
34 JAGN1 84522
Two-hybrid Homo sapiens
35 COPB1 1315
Affinity Capture-MS Homo sapiens
36 UBAC2 337867
Affinity Capture-MS Homo sapiens
37 ESRRB  
Affinity Capture-MS Homo sapiens
38 CDH1 999
Proximity Label-MS Homo sapiens
39 TMED5 50999
Affinity Capture-MS Homo sapiens
40 VAPB 9217
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
41 GLB1 2720
Affinity Capture-MS Homo sapiens
42 PEX14 5195
Affinity Capture-MS Homo sapiens
43 YWHAQ 10971
Affinity Capture-MS Homo sapiens
44 TUBA1C 84790
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 PIGS 94005
Affinity Capture-MS Homo sapiens
46 PRKAR1B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 PMAIP1  
Affinity Capture-MS Homo sapiens
48 VDAC2 7417
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
49 SEC61B 10952
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 TMED1 11018
Affinity Capture-MS Homo sapiens
51 OSBPL7  
Affinity Capture-MS Homo sapiens
52 PTAR1 375743
Affinity Capture-MS Homo sapiens
53 TMEM35  
Two-hybrid Homo sapiens
54 SSR4 6748
Affinity Capture-MS Homo sapiens
55 REEP5 7905
Proximity Label-MS Homo sapiens
56 CDS2 8760
Affinity Capture-MS Homo sapiens
57 STK3 6788
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 TMPO 7112
Affinity Capture-MS Homo sapiens
59 MRTO4 51154
Co-fractionation Homo sapiens
60 BTNL9  
Affinity Capture-MS Homo sapiens
61 NDUFA13 51079
Affinity Capture-MS Homo sapiens
62 LRRC59 55379
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 LMNB1 4001
Proximity Label-MS Homo sapiens
64 PRKAR1A 5573
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 GOLT1B 51026
Affinity Capture-MS Homo sapiens
66 BCAP31 10134
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
67 YWHAZ 7534
Affinity Capture-MS Homo sapiens
68 FKBP8 23770
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
69 FN1 2335
Affinity Capture-MS Homo sapiens
70 CDC42 998
Co-fractionation Homo sapiens
71 PITPNA 5306
Co-fractionation Homo sapiens
72 TMEM86B  
Two-hybrid Homo sapiens
73 FBXW11  
Affinity Capture-MS Homo sapiens
74 PHTF2  
Affinity Capture-MS Homo sapiens
75 SOAT1 6646
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
76 ALDH3A2 224
Affinity Capture-MS Homo sapiens
77 RPA3 6119
Proximity Label-MS Homo sapiens
78 WRB 7485
Affinity Capture-MS Homo sapiens
79 COX6C 1345
Affinity Capture-MS Homo sapiens
80 TMCO1 54499
Affinity Capture-MS Homo sapiens
81 ITPRIPL1  
Affinity Capture-MS Homo sapiens
82 ARL6IP1 23204
Affinity Capture-MS Homo sapiens
83 NCLN 56926
Affinity Capture-MS Homo sapiens
84 DUSP9  
Affinity Capture-MS Homo sapiens
85 NDUFA10 4705
Affinity Capture-MS Homo sapiens
86 CYP2C9  
Proximity Label-MS Homo sapiens
87 KIDINS220 57498
Affinity Capture-MS Homo sapiens
88 EPT1 85465
Affinity Capture-MS Homo sapiens
89 NFATC2  
Affinity Capture-MS Homo sapiens
90 HIST1H2AJ 8331
Affinity Capture-MS Homo sapiens
91 CEPT1 10390
Affinity Capture-MS Homo sapiens
92 TMX2 51075
Two-hybrid Homo sapiens
93 RPS16 6217
Co-fractionation Homo sapiens
94 DDX46 9879
Co-fractionation Homo sapiens
95 YWHAH 7533
Affinity Capture-MS Homo sapiens
96 PIEZO1 9780
Affinity Capture-MS Homo sapiens
97 ZFYVE27 118813
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
98 ITPR3 3710
Affinity Capture-MS Homo sapiens
99 TKT 7086
Co-fractionation Homo sapiens
100 RPS15A 6210
Co-fractionation Homo sapiens
101 Rassf1  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
102 PTPN5  
Affinity Capture-MS Homo sapiens
103 RAB2A 5862
Affinity Capture-MS Homo sapiens
104 PSMA5 5686
Affinity Capture-MS Homo sapiens
105 RAB11A 8766
Proximity Label-MS Homo sapiens
106 ACO2 50
Co-fractionation Homo sapiens
107 GBE1 2632
Affinity Capture-MS Homo sapiens
108 CISD2 493856
Affinity Capture-MS Homo sapiens
109 RAB5C 5878
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
110 TAP1 6890
Affinity Capture-MS Homo sapiens
111 CCDC40  
Affinity Capture-MS Homo sapiens
112 NDUFS6  
Affinity Capture-MS Homo sapiens
113 ASB14  
Affinity Capture-MS Homo sapiens
114 DERL1 79139
Proximity Label-MS Homo sapiens
115 C2CD2L 9854
Affinity Capture-MS Homo sapiens
116 PTPN12 5782
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
117 OSBPL10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
118 ZBTB22  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
119 SACM1L 22908
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
120 LAMP3  
Proximity Label-MS Homo sapiens
121 SLC39A4 55630
Affinity Capture-MS Homo sapiens
122 GJA1 2697
Proximity Label-MS Homo sapiens
123 BTF3 689
Affinity Capture-MS Homo sapiens
124 ADRB2  
PCA Homo sapiens
Two-hybrid Homo sapiens
125 SPTLC1 10558
Affinity Capture-MS Homo sapiens
126 SURF4 6836
Affinity Capture-MS Homo sapiens
127 NDUFA12 55967
Affinity Capture-MS Homo sapiens
128 VAMP2 6844
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
129 COPA 1314
Affinity Capture-MS Homo sapiens
130 FAXC  
Affinity Capture-MS Homo sapiens
131 AFTPH  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
132 NDUFS2 4720
Affinity Capture-MS Homo sapiens
133 ABCD1 215
Affinity Capture-MS Homo sapiens
134 LGALS3BP 3959
Affinity Capture-MS Homo sapiens
135 EBP  
Two-hybrid Homo sapiens
136 OPRM1 4988
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
137 OSBP 5007
Two-hybrid Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
138 NDUFA5 4698
Affinity Capture-MS Homo sapiens
139 PITPNM1 9600
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
140 GPRC5B 51704
Affinity Capture-MS Homo sapiens
141 RAB5B 5869
Co-fractionation Homo sapiens
142 ATP2A3 489
Affinity Capture-MS Homo sapiens
143 NEU1 4758
Affinity Capture-MS Homo sapiens
144 SEC11C 90701
Two-hybrid Homo sapiens
145 VCAM1 7412
Affinity Capture-MS Homo sapiens
146 DDX6 1656
Affinity Capture-MS Homo sapiens
147 NDUFV3 4731
Affinity Capture-MS Homo sapiens
148 RBM42  
Affinity Capture-MS Homo sapiens
149 EBAG9 9166
Two-hybrid Homo sapiens
150 LEPROTL1 23484
Two-hybrid Homo sapiens
151 PRNP 5621
Affinity Capture-MS Homo sapiens
152 LMAN1 3998
Proximity Label-MS Homo sapiens
153 KIAA1715 80856
Proximity Label-MS Homo sapiens
154 CALM2 805
Affinity Capture-MS Homo sapiens
155 ATP6V1G1 9550
Affinity Capture-MS Homo sapiens
156 PANX1 24145
Proximity Label-MS Homo sapiens
157 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
158 OPRK1  
Affinity Capture-Western Homo sapiens
159 SLC16A7 9194
Two-hybrid Homo sapiens
160 STOM 2040
Affinity Capture-MS Homo sapiens
161 UBAP2L 9898
Co-fractionation Homo sapiens
162 ZMYM1 79830
Affinity Capture-MS Homo sapiens
163 NOL11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
164 TMEM43 79188
Affinity Capture-MS Homo sapiens
165 PITPNM2 57605
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
166 YIF1A 10897
Affinity Capture-MS Homo sapiens
167 TRPM7 54822
Affinity Capture-MS Homo sapiens
168 VAMP1 6843
Reconstituted Complex Homo sapiens
169 UQCRC1 7384
Affinity Capture-MS Homo sapiens
170 COMT 1312
Affinity Capture-MS Homo sapiens
171 RPLP0 6175
Co-fractionation Homo sapiens
172 CXADR 1525
Proximity Label-MS Homo sapiens
173 ATP6V1E1 529
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
174 TMED9 54732
Affinity Capture-MS Homo sapiens
175 RPN2 6185
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
176 CANX 821
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
177 ATL3 25923
Affinity Capture-MS Homo sapiens
178 EMC8 10328
Affinity Capture-MS Homo sapiens
179 RAB5A 5868
Proximity Label-MS Homo sapiens
180 EIF6 3692
Co-fractionation Homo sapiens
181 UBXN7 26043
Affinity Capture-MS Homo sapiens
182 PNP 4860
Co-fractionation Homo sapiens
183 SREBF1 6720
Affinity Capture-Western Homo sapiens
184 Rmdn3  
Affinity Capture-MS Mus musculus
185 TJP1 7082
Co-fractionation Homo sapiens
186 RASSF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
187 EGFR 1956
PCA Homo sapiens
Affinity Capture-MS Homo sapiens
188 HSD17B10 3028
Co-fractionation Homo sapiens
189 ITPRIP  
Affinity Capture-MS Homo sapiens
190 MORF4L1  
Co-fractionation Homo sapiens
191 KLRD1  
Affinity Capture-MS Homo sapiens
192 Cep152  
Affinity Capture-MS Mus musculus
193 SYP  
Affinity Capture-MS Homo sapiens
194 MYC  
Affinity Capture-MS Homo sapiens
195 ATP2A1 487
Proximity Label-MS Homo sapiens
196 JMY  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
197 NMD3 51068
Affinity Capture-MS Homo sapiens
198 WDR44 54521
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
199 PCM1 5108
Affinity Capture-MS Homo sapiens
200 MPRIP 23164
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
201 NDUFV2 4729
Affinity Capture-MS Homo sapiens
202 LMNA 4000
Proximity Label-MS Homo sapiens
203 PHGDH 26227
Co-fractionation Homo sapiens
204 OST4  
Affinity Capture-MS Homo sapiens
205 NDUFS5 4725
Affinity Capture-MS Homo sapiens
206 SYNRG 11276
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
207 RBM8A 9939
Affinity Capture-MS Homo sapiens
208 HEATR5B 54497
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
209 TTC1 7265
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
210 SLC35B1 10237
Two-hybrid Homo sapiens
211 PGRMC1 10857
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
212 RTN3 10313
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
213 GOSR1 9527
Affinity Capture-MS Homo sapiens
214 SF3B4 10262
Co-fractionation Homo sapiens
215 XPR1 9213
Affinity Capture-MS Homo sapiens
216 YWHAE 7531
Affinity Capture-MS Homo sapiens
217 Arhgap30  
Affinity Capture-MS Mus musculus
218 CMTR1 23070
Affinity Capture-MS Homo sapiens
219 MMGT1 93380
Affinity Capture-MS Homo sapiens
220 RPS26 6231
Co-fractionation Homo sapiens
221 ERGIC2 51290
Proximity Label-MS Homo sapiens
222 OSBPL3 26031
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
223 SPCS2 9789
Affinity Capture-MS Homo sapiens
224 C1QBP 708
Affinity Capture-MS Homo sapiens
225 KRAS 3845
Proximity Label-MS Homo sapiens
226 CKAP4 10970
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
227 PTRF 284119
Affinity Capture-MS Homo sapiens
228 ZDBF2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
229 NDUFB4 4710
Affinity Capture-MS Homo sapiens
230 ATAD1 84896
Affinity Capture-MS Homo sapiens
231 ATP6V1B2 526
Affinity Capture-MS Homo sapiens
232 HACD3 51495
Affinity Capture-MS Homo sapiens
233 RAB1A 5861
Co-fractionation Homo sapiens
234 NDUFS1 4719
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
235 MARCKS 4082
Proximity Label-MS Homo sapiens
236 PARD3 56288
Affinity Capture-MS Homo sapiens
237 AKAP11 11215
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
238 TMUB1  
Affinity Capture-MS Homo sapiens
239 UQCRB 7381
Co-fractionation Homo sapiens
240 ARCN1 372
Affinity Capture-MS Homo sapiens
241 SYNE2 23224
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
242 PTPN1 5770
Proximity Label-MS Homo sapiens
243 Actb 11461
Affinity Capture-MS Mus musculus
244 ASPH 444
Affinity Capture-MS Homo sapiens
245 STX4 6810
Proximity Label-MS Homo sapiens
246 RTN4 57142
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
247 APOD 347
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
248 DEGS1  
Affinity Capture-MS Homo sapiens
249 CAPZB 832
Affinity Capture-MS Homo sapiens
250 MGST1 4257
Co-fractionation Homo sapiens
251 PRKCDBP 112464
Affinity Capture-MS Homo sapiens
252 NDUFB8 4714
Affinity Capture-MS Homo sapiens
253 MCM2 4171
Affinity Capture-MS Homo sapiens
254 COPB2 9276
Affinity Capture-MS Homo sapiens
255 EIF3B 8662
Co-fractionation Homo sapiens
256 RAB3B 5865
Proximity Label-MS Homo sapiens
257 VKORC1 79001
Affinity Capture-MS Homo sapiens
258 LSG1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
259 SSR1 6745
Proximity Label-MS Homo sapiens
260 FAM83G  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
261 ITGA4 3676
Affinity Capture-MS Homo sapiens
262 CCDC47 57003
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
263 LOC101929876 101929876
Co-fractionation Homo sapiens
264 NDUFV1 4723
Affinity Capture-MS Homo sapiens
265 ATG16L1 55054
Affinity Capture-MS Homo sapiens
266 ESYT2 57488
Affinity Capture-MS Homo sapiens
267 CLN8 2055
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
268 KCNA4  
Affinity Capture-MS Homo sapiens
269 METTL7A 25840
Proximity Label-MS Homo sapiens
270 SERPINB9 5272
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
271 NUP155 9631
Proximity Label-MS Homo sapiens
272 PXMP2  
Proximity Label-MS Homo sapiens
273 EIF2AK3  
Affinity Capture-MS Homo sapiens
274 EIF3K 27335
Affinity Capture-MS Homo sapiens
275 SCFD1 23256
Affinity Capture-MS Homo sapiens
276 COPE 11316
Affinity Capture-MS Homo sapiens
277 CHCHD3 54927
Affinity Capture-MS Homo sapiens
278 ASNA1 439
Affinity Capture-MS Homo sapiens
279 C6orf47  
Affinity Capture-MS Homo sapiens
280 RPL5 6125
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
281 NTRK1 4914
Affinity Capture-MS Homo sapiens
282 OSBPL2 9885
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
283 TACC1 6867
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
284 RPA4  
Proximity Label-MS Homo sapiens
285 RPN1 6184
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
286 ARHGEF12 23365
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
287 TECR 9524
Affinity Capture-MS Homo sapiens
288 NANP 140838
Affinity Capture-MS Homo sapiens
289 TMEM33 55161
Affinity Capture-MS Homo sapiens
290 SCN3B  
Two-hybrid Homo sapiens
291 GNG5 2787
Affinity Capture-MS Homo sapiens
292 FAM73B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
293 RMDN3 55177
Proximity Label-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
294 PCTP  
Affinity Capture-MS Homo sapiens
295 SCRN1 9805
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
296 FAM170A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
297 SLC25A12 8604
Affinity Capture-MS Homo sapiens
298 METTL14  
Affinity Capture-MS Homo sapiens
299 POR 5447
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
300 OSBPL6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
301 HSD3B7 80270
Proximity Label-MS Homo sapiens
302 ENDOD1 23052
Affinity Capture-MS Homo sapiens
303 STIM1 6786
Proximity Label-MS Homo sapiens
304 NIPAL1  
Affinity Capture-MS Homo sapiens
305 FBXO6 26270
Affinity Capture-MS Homo sapiens
306 COX6B1 1340
Affinity Capture-MS Homo sapiens
307 YIPF5 81555
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
308 GOSR2 9570
Affinity Capture-MS Homo sapiens
309 OCIAD1 54940
Two-hybrid Homo sapiens
310 OSBPL11 114885
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
311 LRRK1 79705
Affinity Capture-MS Homo sapiens
312 MTMR12 54545
Affinity Capture-MS Homo sapiens
313 FAM134C 162427
Two-hybrid Homo sapiens
314 C3orf18  
Affinity Capture-MS Homo sapiens
315 EMC2 9694
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
316 RAB9A 9367
Proximity Label-MS Homo sapiens
317 SLC22A15  
Affinity Capture-MS Homo sapiens
318 RAB3GAP1 22930
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
319 RMDN2 151393
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
320 CACNG1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
321 STK4 6789
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
322 ISLR 3671
Affinity Capture-MS Homo sapiens
323 H2AFY 9555
Affinity Capture-MS Homo sapiens
324 OSBPL1A 114876
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
325 FLOT1 10211
Affinity Capture-MS Homo sapiens
326 ACBD5 91452
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
327 IMMT 10989
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
328 MBOAT7 79143
Affinity Capture-MS Homo sapiens
329 RASSF3 283349
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
330 SPCS3 60559
Affinity Capture-MS Homo sapiens
331 PHB2 11331
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
332 TMED10 10972
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
333 GPR89A  
Affinity Capture-MS Homo sapiens
334 SOD2 6648
Co-fractionation Homo sapiens
335 RAB3GAP2 25782
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
336 SIN3A  
Co-fractionation Homo sapiens
337 ERLIN1 10613
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
338 LDLRAD1  
Affinity Capture-MS Homo sapiens
339 KIAA1429 25962
Affinity Capture-MS Homo sapiens
340 GABARAPL2 11345
Affinity Capture-Western Homo sapiens
341 ERLIN2 11160
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
342 FLOT2 2319
Affinity Capture-MS Homo sapiens
343 GNB1 2782
Affinity Capture-MS Homo sapiens
344 ERGIC1 57222
Proximity Label-MS Homo sapiens
345 DDX58 23586
Affinity Capture-MS Homo sapiens
346 PDZD8 118987
Affinity Capture-MS Homo sapiens
347 NDUFS8 4728
Affinity Capture-MS Homo sapiens
348 NDUFA2 4695
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
349 SEC11A 23478
Affinity Capture-MS Homo sapiens
350 KCNB1  
FRET Homo sapiens
351 RAB7A 7879
Proximity Label-MS Homo sapiens
352 ROBO2 6092
Affinity Capture-MS Homo sapiens
353 TMEM38B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
354 STT3B 201595
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
355 VDAC3 7419
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
356 CAV1 857
Affinity Capture-MS Homo sapiens
357 MGST3 4259
Affinity Capture-MS Homo sapiens
358 EIF5 1983
Affinity Capture-MS Homo sapiens
359 PSTPIP2 9050
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
360 UBE2H 7328
Affinity Capture-MS Homo sapiens
361 INSIG1  
Affinity Capture-Western Homo sapiens
362 HSD17B11 51170
Proximity Label-MS Homo sapiens
Two-hybrid Homo sapiens
363 OSBP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
364 AP2B1 163
Co-fractionation Homo sapiens
365 VAPA 9218
PCA Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
PCA Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
366 ANXA3 306
Co-fractionation Homo sapiens
367 VPS13A 23230
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
368 LAMP2 3920
Proximity Label-MS Homo sapiens
369 DNAJC25 548645
Proximity Label-MS Homo sapiens
370 CD79A  
Two-hybrid Homo sapiens
371 GKN1  
Two-hybrid Homo sapiens
372 HSD17B12 51144
Affinity Capture-MS Homo sapiens
373 APP 351
Reconstituted Complex Homo sapiens
374 PDE2A  
Affinity Capture-MS Homo sapiens
375 ASB17  
Affinity Capture-MS Homo sapiens
376 B3GAT1  
Proximity Label-MS Homo sapiens
377 DYRK1A 1859
Affinity Capture-MS Homo sapiens
378 KLF8  
Affinity Capture-MS Homo sapiens
379 NDUFA7 4701
Affinity Capture-MS Homo sapiens
380 GPR128  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
381 YWHAG 7532
Affinity Capture-MS Homo sapiens
382 JTB 10899
Affinity Capture-MS Homo sapiens
383 ABCE1 6059
Co-fractionation Homo sapiens
384 PGRMC2 10424
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
385 DNAJC16  
Proximity Label-MS Homo sapiens
386 SRI 6717
Affinity Capture-MS Homo sapiens
387 ATP6V0D1 9114
Affinity Capture-MS Homo sapiens
388 RAB35 11021
Proximity Label-MS Homo sapiens
389 NDUFA6  
Affinity Capture-MS Homo sapiens
390 TMEM63B 55362
Affinity Capture-MS Homo sapiens
391 RAB1B 81876
Co-fractionation Homo sapiens
392 LTBR 4055
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
393 STOML2 30968
Affinity Capture-MS Homo sapiens
394 H2AFZ 3015
Affinity Capture-MS Homo sapiens
395 DDOST 1650
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
396 NDUFS4 4724
Affinity Capture-MS Homo sapiens
397 IKBIP 121457
Affinity Capture-MS Homo sapiens
398 EMD 2010
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
399 RB1CC1 9821
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
400 SCAP  
Affinity Capture-Western Homo sapiens
401 ATF2  
Affinity Capture-MS Homo sapiens
402 CTSA 5476
Affinity Capture-MS Homo sapiens
403 SMARCA4 6597
Affinity Capture-MS Homo sapiens
404 SREBF2 6721
Affinity Capture-Western Homo sapiens
405 VCP 7415
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
406 ZMPSTE24 10269
Affinity Capture-MS Homo sapiens
407 CHCHD6 84303
Affinity Capture-MS Homo sapiens
408 DNAJC30  
Affinity Capture-MS Homo sapiens
409 MICAL3 57553
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
410 RHOT2 89941
Proximity Label-MS Homo sapiens
411 ELOVL5 60481
Proximity Label-MS Homo sapiens
412 PRKACB 5567
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
413 COX4I1 1327
Co-fractionation Homo sapiens
414 TEX2 55852
Affinity Capture-MS Homo sapiens
415 PHB 5245
Affinity Capture-MS Homo sapiens
416 SEC63 11231
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
417 TOMM40 10452
Co-fractionation Homo sapiens
418 COX5B 1329
Affinity Capture-MS Homo sapiens
419 FANCD2  
Affinity Capture-MS Homo sapiens
420 PITPNM3 83394
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
421 TMIE  
Two-hybrid Homo sapiens
422 ZFPL1 7542
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
423 NDUFA9 4704
Affinity Capture-MS Homo sapiens
424 UQCRC2 7385
Co-fractionation Homo sapiens
425 LAMP1 3916
Proximity Label-MS Homo sapiens
426 RTN2 6253
Affinity Capture-MS Homo sapiens
427 ARF6 382
Proximity Label-MS Homo sapiens
428 HSD17B13  
Two-hybrid Homo sapiens
429 NXF1 10482
Two-hybrid Homo sapiens
430 ACBD4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
431 TCIRG1 10312
Co-fractionation Homo sapiens
432 CCDC127  
Affinity Capture-MS Homo sapiens
433 PRKACA 5566
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
434 TOMM6  
Co-fractionation Homo sapiens
435 ATP6V1A 523
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
436 MOSPD2 158747
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
437 FNDC3A 22862
Affinity Capture-MS Homo sapiens
438 SCD 6319
Affinity Capture-MS Homo sapiens
439 VDAC1 7416
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
440 LBR 3930
Affinity Capture-MS Homo sapiens
441 ARHGEF18 23370
Affinity Capture-MS Homo sapiens
442 NACAD  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
443 AMY1C 278
Affinity Capture-MS Homo sapiens
444 ORC3  
Affinity Capture-MS Homo sapiens
445 TMEM120B  
Affinity Capture-MS Homo sapiens
446 YWHAB 7529
Affinity Capture-MS Homo sapiens
447 PIGK 10026
Affinity Capture-MS Homo sapiens
448 SRP72 6731
Affinity Capture-MS Homo sapiens
449 HIST1H2BD 3017
Affinity Capture-MS Homo sapiens
450 ATP2A2 488
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
451 ARF4 378
Co-fractionation Homo sapiens
452 SPCS1 28972
Affinity Capture-MS Homo sapiens
453 SEC62 7095
Proximity Label-MS Homo sapiens
454 CYB5R3 1727
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
455 EIF5A 1984
Co-fractionation Homo sapiens
456 DNAJC1 64215
Proximity Label-MS Homo sapiens
457 TMEM229B  
Two-hybrid Homo sapiens
458 EMC3 55831
Affinity Capture-MS Homo sapiens
459 NDUFB11 54539
Affinity Capture-MS Homo sapiens
460 ESYT1 23344
Affinity Capture-MS Homo sapiens
461 USP20  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here