Gene description for STX1A
Gene name	syntaxin 1A (brain)
Gene symbol	STX1A
Other names/aliases	HPC-1 P35-1 STX1 SYN1A
Species	Homo sapiens
Database cross references - STX1A
ExoCarta	ExoCarta_6804
Entrez Gene	6804
HGNC	11433
MIM	186590
UniProt	Q16623
STX1A identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells	25944692

Gene ontology annotations for STX1A

Molecular Function     protein binding GO:0005515 IPI     protein N-terminus binding GO:0047485 IEA     calcium channel inhibitor activity GO:0019855 IEA     protein binding, bridging GO:0030674 IEA     kinase binding GO:0019900 IPI     glycoprotein binding GO:0001948 IEA     ATP-dependent protein binding GO:0043008 IEA     calcium-dependent protein binding GO:0048306 IEA     chloride channel inhibitor activity GO:0019869 IDA     protein domain specific binding GO:0019904 IEA     SNARE binding GO:0000149 IBA     protein heterodimerization activity GO:0046982 IEA     SNAP receptor activity GO:0005484 IBA     myosin head/neck binding GO:0032028 IEA     myosin binding GO:0017022 IBA Biological Process     regulation of insulin secretion GO:0050796 TAS     synaptic vesicle docking GO:0016081 IEA     small molecule metabolic process GO:0044281 TAS     positive regulation of calcium ion-dependent exocytosis GO:0045956 ISS     exocytosis GO:0006887 IBA     regulation of synaptic vesicle priming GO:0010807 IEA     glutamate secretion GO:0014047 TAS     intracellular protein transport GO:0006886 IBA     energy reserve metabolic process GO:0006112 TAS     positive regulation of norepinephrine secretion GO:0010701 ISS     vesicle docking GO:0048278 IBA     synaptic vesicle fusion to presynaptic membrane GO:0031629 IBA     positive regulation of neurotransmitter secretion GO:0001956 IEA     response to gravity GO:0009629 IEA     cellular protein metabolic process GO:0044267 TAS     calcium ion-dependent exocytosis GO:0017156 IEA     synaptic transmission GO:0007268 TAS     positive regulation of excitatory postsynaptic membrane potential GO:2000463 IEA     positive regulation of catecholamine secretion GO:0033605 ISS     neurotransmitter secretion GO:0007269 TAS     secretion by cell GO:0032940 IDA Subcellular Localization     secretory granule GO:0030141 IEA     synaptic vesicle GO:0008021 IBA     plasma membrane GO:0005886 TAS     cytosol GO:0005829 TAS     extracellular region GO:0005576 IEA     synaptobrevin 2-SNAP-25-syntaxin-1a complex GO:0070044 IEA     cell junction GO:0030054 IEA     synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex GO:0070032 IEA     synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex GO:0070033 IEA     actomyosin GO:0042641 IEA     SNARE complex GO:0031201 TAS     integral component of membrane GO:0016021 IBA     neuron projection GO:0043005 IDA     synaptic vesicle membrane GO:0030672 IEA     endomembrane system GO:0012505 IBA     voltage-gated potassium channel complex GO:0008076 ISS