Gene description for Stxbp1
Gene name	syntaxin binding protein 1
Gene symbol	Stxbp1
Other names/aliases	ANC18HA Munc18-1 NSEC1A Sec1 Unc18-1 n-sec1 nSec1 rbSec1 rbSec1A rbSec1B
Species	Rattus norvegicus
Database cross references - Stxbp1
ExoCarta	ExoCarta_25558
Vesiclepedia	VP_25558
Entrez Gene	25558
UniProt	P61765
Stxbp1 identified in exosomes derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Stxbp1

Molecular Function     SNARE binding GO:0000149 IDA     protein binding GO:0005515 IPI     syntaxin-1 binding GO:0017075 IBA     syntaxin-1 binding GO:0017075 IDA     syntaxin-1 binding GO:0017075 ISO     protein kinase binding GO:0019901 IPI     protein domain specific binding GO:0019904 IDA     syntaxin binding GO:0019905 IDA     syntaxin binding GO:0019905 ISO     identical protein binding GO:0042802 IPI     phospholipase binding GO:0043274 IDA     molecular adaptor activity GO:0060090 EXP Biological Process     platelet degranulation GO:0002576 ISO     developmental process involved in reproduction GO:0003006 IMP     intracellular protein transport GO:0006886 IBA     exocytosis GO:0006887 ISO     vesicle docking involved in exocytosis GO:0006904 IBA     vesicle docking involved in exocytosis GO:0006904 ISO     vesicle docking involved in exocytosis GO:0006904 ISO     vesicle docking involved in exocytosis GO:0006904 ISS     neurotransmitter secretion GO:0007269 ISO     neuromuscular synaptic transmission GO:0007274 ISO     axon target recognition GO:0007412 ISO     regulation of synaptic vesicle priming GO:0010807 IDA     regulation of synaptic vesicle priming GO:0010807 IMP     protein transport GO:0015031 IEA     synaptic vesicle priming GO:0016082 ISO     synaptic vesicle maturation GO:0016188 ISO     vesicle-mediated transport GO:0016192 IEA     negative regulation of protein-containing complex assembly GO:0031333 IDA     regulation of vesicle fusion GO:0031338 IDA     negative regulation of synaptic transmission, GABAergic GO:0032229 ISO     response to estradiol GO:0032355 IEP     SNARE complex assembly GO:0035493 ISO     negative regulation of SNARE complex assembly GO:0035544 TAS     positive regulation of mast cell degranulation GO:0043306 IMP     negative regulation of neuron apoptotic process GO:0043524 ISO     positive regulation of exocytosis GO:0045921 IMP     positive regulation of calcium ion-dependent exocytosis GO:0045956 ISO     protein stabilization GO:0050821 IDA     neuron apoptotic process GO:0051402 ISO     establishment of localization in cell GO:0051649 ISO     long-term synaptic depression GO:0060292 ISO     platelet aggregation GO:0070527 ISO     cellular response to type II interferon GO:0071346 ISO     protein localization to plasma membrane GO:0072659 ISO     presynaptic dense core vesicle exocytosis GO:0099525 IBA     positive regulation of vesicle docking GO:0106022 IDA     positive regulation of glutamate secretion, neurotransmission GO:1903296 IMP     regulation of acrosomal vesicle exocytosis GO:2000367 ISO Subcellular Localization     nucleoplasm GO:0005654 IEA     nucleoplasm GO:0005654 ISO     cytoplasm GO:0005737 IDA     cytosol GO:0005829 IEA     cytosol GO:0005829 ISO     cytosol GO:0005829 TAS     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 ISO     membrane GO:0016020 IEA     secretory granule GO:0030141 IBA     axon GO:0030424 IDA     axon GO:0030424 ISO     platelet alpha granule GO:0031091 ISO     protein-containing complex GO:0032991 IDA     terminal bouton GO:0043195 HDA     phagocytic vesicle GO:0045335 ISO     perinuclear region of cytoplasm GO:0048471 IDA     parallel fiber to Purkinje cell synapse GO:0098688 ISO     presynapse GO:0098793 IDA     postsynapse GO:0098794 IDA     presynaptic active zone cytoplasmic component GO:0098831 ISO     extrinsic component of presynaptic membrane GO:0098888 ISO     glutamatergic synapse GO:0098978 ISO     presynaptic cytosol GO:0099523 ISO