Gene description for C14orf1
Gene name chromosome 14 open reading frame 1
Gene symbol C14orf1
Other names/aliases ERG28
NET51
Species Homo sapiens
 Database cross references - C14orf1
ExoCarta ExoCarta_11161
Entrez Gene 11161
HGNC 1187
MIM 604576
UniProt Q9UKR5  
 C14orf1 identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for C14orf1
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    sterol biosynthetic process GO:0016126 IEA
    biological_process GO:0008150 ND
Subcellular Localization
    integral component of membrane GO:0016021 NAS
    endoplasmic reticulum membrane GO:0005789 IEA
    transport vesicle GO:0030133 IDA
 Experiment description of studies that identified C14orf1 in exosomes
1
Experiment ID 191
ISEV standards
EV Biophysical techniques
Alix
EV Cytosolic markers
CD81|CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for C14orf1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 POLR2C 5432
Two-hybrid Homo sapiens
2 HSU79303  
Two-hybrid Homo sapiens
3 KLHL20  
Two-hybrid Homo sapiens
4 SAT  
Two-hybrid Homo sapiens
5 NDUFA4L2  
Two-hybrid Homo sapiens
6 PQBP1  
Two-hybrid Homo sapiens
7 COX17  
Two-hybrid Homo sapiens
8 ZNF24  
Two-hybrid Homo sapiens
9 SNRPG 6637
Two-hybrid Homo sapiens
10 SEPHS1  
Two-hybrid Homo sapiens
11 NAT9  
Two-hybrid Homo sapiens
12 SULT1E1  
Two-hybrid Homo sapiens
13 TK1 7083
Two-hybrid Homo sapiens
14 MRPS12  
Two-hybrid Homo sapiens
15 HMGB1 3146
Two-hybrid Homo sapiens
16 TNRC4  
Two-hybrid Homo sapiens
17 FAS 355
Two-hybrid Homo sapiens
18 SERPINB9 5272
Two-hybrid Homo sapiens
19 HSPE1 3336
Two-hybrid Homo sapiens
20 PFN1 5216
Two-hybrid Homo sapiens
21 SNRPB 6628
Two-hybrid Homo sapiens
22 CDK5RAP2 55755
Two-hybrid Homo sapiens
23 ALDH2 217
Two-hybrid Homo sapiens
24 ZFP64  
Two-hybrid Homo sapiens
25 POLE2  
Two-hybrid Homo sapiens
26 PXMP3  
Two-hybrid Homo sapiens
27 HYLS1  
Two-hybrid Homo sapiens
28 CREB1  
Two-hybrid Homo sapiens
29 TFG 10342
Two-hybrid Homo sapiens
30 CDC42 998
Two-hybrid Homo sapiens
31 CCL18  
Two-hybrid Homo sapiens
32 POLR3F  
Two-hybrid Homo sapiens
33 BTBD2  
Two-hybrid Homo sapiens
34 FXR1 8087
Two-hybrid Homo sapiens
35 PHYHIP 9796
Two-hybrid Homo sapiens
36 DYNLL1 8655
Two-hybrid Homo sapiens
37 PPP1R8 5511
Two-hybrid Homo sapiens
38 PAFAH1B3 5050
Two-hybrid Homo sapiens
39 PCDHA4  
Two-hybrid Homo sapiens
40 S100A8 6279
Two-hybrid Homo sapiens
41 NSF 4905
Two-hybrid Homo sapiens
42 MPHOSPH6  
Two-hybrid Homo sapiens
43 HNRNPUL1 11100
Two-hybrid Homo sapiens
44 CRADD  
Two-hybrid Homo sapiens
45 MRPL38  
Two-hybrid Homo sapiens
46 CSTF2  
Two-hybrid Homo sapiens
47 BAIAP2 10458
Two-hybrid Homo sapiens
48 RAB27A 5873
Two-hybrid Homo sapiens
49 LSM2  
Two-hybrid Homo sapiens
50 HNRNPH3 3189
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which C14orf1 is involved
No pathways found





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