Gene description for SULT1E1
Gene name sulfotransferase family 1E, estrogen-preferring, member 1
Gene symbol SULT1E1
Other names/aliases EST
EST-1
ST1E1
STE
Species Homo sapiens
 Database cross references - SULT1E1
ExoCarta ExoCarta_6783
Vesiclepedia VP_6783
Entrez Gene 6783
HGNC 11377
MIM 600043
UniProt P49888  
 SULT1E1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for SULT1E1
Molecular Function
    steroid binding GO:0005496 IEA
    protein binding GO:0005515 IPI
    steroid sulfotransferase activity GO:0050294 TAS
    flavonol 3-sulfotransferase activity GO:0047894 IDA
    estrone sulfotransferase activity GO:0004304 IEA
Biological Process
    xenobiotic metabolic process GO:0006805 TAS
    3'-phosphoadenosine 5'-phosphosulfate metabolic process GO:0050427 TAS
    estrogen metabolic process GO:0008210 IDA
    sulfation GO:0051923 IDA
    small molecule metabolic process GO:0044281 TAS
    female pregnancy GO:0007565 IEA
    positive regulation of fat cell differentiation GO:0045600 IMP
    steroid metabolic process GO:0008202 TAS
Subcellular Localization
    cytosol GO:0005829 TAS
 Experiment description of studies that identified SULT1E1 in exosomes
1
Experiment ID 488
MISEV standards
✔
EM
EV Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
EV Enriched markers
✔
CANX
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for SULT1E1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DKFZP564O0523  
Two-hybrid Homo sapiens
2 UNC119 9094
Two-hybrid Homo sapiens
3 MGC15730  
Two-hybrid Homo sapiens
4 TP53 7157
Two-hybrid Homo sapiens
5 EEF1A1 1915
Two-hybrid Homo sapiens
6 FLJ10094  
Two-hybrid Homo sapiens
7 C14orf1 11161
Two-hybrid Homo sapiens
8 SULT2B1 6820
Two-hybrid Homo sapiens
9 COPS6 10980
Two-hybrid Homo sapiens
10 SETDB1  
Two-hybrid Homo sapiens
11 RIF1  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which SULT1E1 is involved
PathwayEvidenceSource
Cytosolic sulfonation of small molecules TAS Reactome





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