Gene description for SULT1E1
Gene name sulfotransferase family 1E, estrogen-preferring, member 1
Gene symbol SULT1E1
Other names/aliases EST
EST-1
ST1E1
STE
Species Homo sapiens
 Database cross references - SULT1E1
ExoCarta ExoCarta_6783
Vesiclepedia VP_6783
Entrez Gene 6783
HGNC 11377
MIM 600043
UniProt P49888  
 SULT1E1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for SULT1E1
Molecular Function
    aryl sulfotransferase activity GO:0004062 IBA
    estrone sulfotransferase activity GO:0004304 IEA
    steroid binding GO:0005496 IEA
    protein binding GO:0005515 IPI
    sulfotransferase activity GO:0008146 IDA
    flavonol 3-sulfotransferase activity GO:0047894 IDA
    steroid sulfotransferase activity GO:0050294 IDA
Biological Process
    ethanol catabolic process GO:0006068 IDA
    estrogen catabolic process GO:0006711 IDA
    steroid metabolic process GO:0008202 TAS
    estrogen metabolic process GO:0008210 IDA
    positive regulation of fat cell differentiation GO:0045600 IMP
    3'-phosphoadenosine 5'-phosphosulfate metabolic process GO:0050427 IDA
    sulfation GO:0051923 IBA
    sulfation GO:0051923 IDA
    sulfation GO:0051923 IDA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    nuclear membrane GO:0031965 IDA
 Experiment description of studies that identified SULT1E1 in exosomes
1
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for SULT1E1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GK  
Co-fractionation Homo sapiens
2 LRIF1  
Two-hybrid Homo sapiens
3 UNC119 9094
Two-hybrid Homo sapiens
4 RBM48  
Two-hybrid Homo sapiens
5 SETDB1  
Two-hybrid Homo sapiens
6 TP53 7157
Two-hybrid Homo sapiens
7 EEF1A1 1915
Two-hybrid Homo sapiens
8 C14orf1 11161
Two-hybrid Homo sapiens
9 SULT2B1 6820
Two-hybrid Homo sapiens
10 COPS6 10980
Two-hybrid Homo sapiens
11 ENOX1  
Two-hybrid Homo sapiens
12 AGL 178
Co-fractionation Homo sapiens
13 PDE9A  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
14 IGSF21  
Two-hybrid Homo sapiens
View the network image/svg+xml



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