Gene description for SULT2B1
Gene name sulfotransferase family, cytosolic, 2B, member 1
Gene symbol SULT2B1
Other names/aliases HSST2
Species Homo sapiens
 Database cross references - SULT2B1
ExoCarta ExoCarta_6820
Vesiclepedia VP_6820
Entrez Gene 6820
HGNC 11459
MIM 604125
UniProt O00204  
 SULT2B1 identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells 34887515    
 Gene ontology annotations for SULT2B1
Molecular Function
    protein binding GO:0005515 IPI
    alcohol sulfotransferase activity GO:0004027 TAS
    steroid sulfotransferase activity GO:0050294 IDA
Biological Process
    xenobiotic metabolic process GO:0006805 TAS
    small molecule metabolic process GO:0044281 TAS
    3'-phosphoadenosine 5'-phosphosulfate metabolic process GO:0050427 TAS
    steroid metabolic process GO:0008202 IDA
    sulfate assimilation GO:0000103 IEA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    endoplasmic reticulum GO:0005783 IEA
    nucleus GO:0005634 IEA
    cytosol GO:0005829 TAS
    intracellular membrane-bounded organelle GO:0043231 IDA
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified SULT2B1 in exosomes
1
Experiment ID 1203
MISEV standards
EM
EV Biophysical techniques
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
EV Enriched markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ.
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
 Protein-protein interactions for SULT2B1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SULT1E1 6783
Two-hybrid Homo sapiens
2 ALS2CR12  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which SULT2B1 is involved
No pathways found





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