Gene description for SULT1A3
Gene name sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
Gene symbol SULT1A3
Other names/aliases HAST
HAST3
M-PST
ST1A3
ST1A3/ST1A4
ST1A5
STM
TL-PST
Species Homo sapiens
 Database cross references - SULT1A3
ExoCarta ExoCarta_6818
Vesiclepedia VP_6818
Entrez Gene 6818
HGNC 11455
MIM 600641
UniProt P0DMN0   P0DMM9  
 SULT1A3 identified in sEVs derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for SULT1A3
Molecular Function
    aryl sulfotransferase activity GO:0004062 IBA
    aryl sulfotransferase activity GO:0004062 IMP
    protein binding GO:0005515 IPI
    sulfotransferase activity GO:0008146 IDA
    sulfate binding GO:0043199 IDA
    amine sulfotransferase activity GO:0047685 IDA
Biological Process
    ethanol catabolic process GO:0006068 IDA
    xenobiotic metabolic process GO:0006805 IDA
    steroid metabolic process GO:0008202 IEA
    flavonoid metabolic process GO:0009812 IDA
    dopamine metabolic process GO:0042417 IMP
    dopamine catabolic process GO:0042420 IDA
    3'-phosphoadenosine 5'-phosphosulfate metabolic process GO:0050427 IDA
    sulfation GO:0051923 IBA
    sulfation GO:0051923 IDA
    cellular response to dopamine GO:1903351 IMP
Subcellular Localization
    cytoplasm GO:0005737 IBA
    cytosol GO:0005829 TAS
 Experiment description of studies that identified SULT1A3 in sEVs
1
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for SULT1A3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 APP 351
Reconstituted Complex Homo sapiens
2 SULT1A1 6817
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 SULT4A1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 SULT1A2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 KHDRBS2  
Two-hybrid Homo sapiens
6 SULT1C3  
Affinity Capture-MS Homo sapiens
7 SULT1C2 6819
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 TTC1 7265
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 SMN1 6606
Two-hybrid Homo sapiens
10 NIF3L1 60491
Two-hybrid Homo sapiens
11 TK1 7083
Two-hybrid Homo sapiens
12 MPPED2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 SULT2B1 6820
Affinity Capture-MS Homo sapiens
14 SHMT1 6470
Two-hybrid Homo sapiens
15 OTUD6B 51633
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which SULT1A3 is involved
No pathways found





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