Gene description for SULT1C2
Gene name sulfotransferase family, cytosolic, 1C, member 2
Gene symbol SULT1C2
Other names/aliases ST1C1
ST1C2
SULT1C1
humSULTC2
Species Homo sapiens
 Database cross references - SULT1C2
ExoCarta ExoCarta_6819
Vesiclepedia VP_6819
Entrez Gene 6819
HGNC 11456
MIM 602385
UniProt O00338  
 SULT1C2 identified in exosomes derived from the following tissue/cell type
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for SULT1C2
Molecular Function
    sulfotransferase activity GO:0008146 IDA
Biological Process
    small molecule metabolic process GO:0044281 TAS
    amine metabolic process GO:0009308 TAS
    3'-phosphoadenosine 5'-phosphosulfate metabolic process GO:0050427 TAS
    xenobiotic metabolic process GO:0006805 TAS
    sulfation GO:0051923 IDA
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    cytosol GO:0005829 TAS
    cytoplasm GO:0005737 TAS
 Experiment description of studies that identified SULT1C2 in exosomes
1
Experiment ID 834
MISEV standards
✔
EM
EV Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
EV Enriched markers
✔
CANX
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 835
MISEV standards
✔
EM
EV Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
EV Enriched markers
✔
CANX
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for SULT1C2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SULT1C2 6819
Invitro Homo sapiens
Invivo Homo sapiens
Affinity Capture-MS Homo sapiens
Invitro Homo sapiens
Invivo Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which SULT1C2 is involved
PathwayEvidenceSource
Cytosolic sulfonation of small molecules TAS Reactome





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