Gene description for TERF1
Gene name	telomeric repeat binding factor (NIMA-interacting) 1
Gene symbol	TERF1
Other names/aliases	PIN2 TRBF1 TRF TRF1 hTRF1-AS t-TRF1
Species	Homo sapiens
Database cross references - TERF1
ExoCarta	ExoCarta_7013
Vesiclepedia	VP_7013
Entrez Gene	7013
HGNC	11728
MIM	600951
UniProt	P54274
TERF1 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for TERF1

Molecular Function     DNA binding GO:0003677 NAS     double-stranded telomeric DNA binding GO:0003691 IBA     double-stranded telomeric DNA binding GO:0003691 IDA     telomerase activity GO:0003720 IBA     telomerase activity GO:0003720 IDA     protein binding GO:0005515 IPI     microtubule binding GO:0008017 IDA     DNA binding, bending GO:0008301 IDA     telomeric DNA binding GO:0042162 IDA     identical protein binding GO:0042802 IPI     protein homodimerization activity GO:0042803 IPI     ankyrin repeat binding GO:0071532 IPI     G-rich strand telomeric DNA binding GO:0098505 IDA Biological Process     telomere maintenance GO:0000723 IMP     telomere maintenance via telomerase GO:0007004 IBA     telomere maintenance via telomerase GO:0007004 IDA     telomere maintenance via telomerase GO:0007004 IMP     negative regulation of DNA replication GO:0008156 IDA     response to xenobiotic stimulus GO:0009410 IEA     telomere capping GO:0016233 IDA     positive regulation of telomere maintenance GO:0032206 NAS     negative regulation of telomere maintenance via telomerase GO:0032211 IGI     negative regulation of telomere maintenance via telomerase GO:0032211 TAS     negative regulation of telomere maintenance via semi-conservative replication GO:0032214 NAS     meiotic telomere clustering GO:0045141 IEA     cell division GO:0051301 IEA     telomeric D-loop disassembly GO:0061820 IGI     t-circle formation GO:0090656 TAS     negative regulation of telomere maintenance via telomere lengthening GO:1904357 TAS     positive regulation of shelterin complex assembly GO:1904792 IMP     negative regulation of establishment of protein localization to telomere GO:1904850 IMP     negative regulation of establishment of RNA localization to telomere GO:1904911 IMP     negative regulation of establishment of protein-containing complex localization to telomere GO:1904914 IC     negative regulation of exonuclease activity GO:1905778 IDA     negative regulation of telomeric D-loop disassembly GO:1905839 IBA     negative regulation of telomeric D-loop disassembly GO:1905839 IDA Subcellular Localization     chromosome, telomeric region GO:0000781 HDA     chromosome, telomeric region GO:0000781 IDA     nuclear telomere cap complex GO:0000783 IBA     nuclear telomere cap complex GO:0000783 IDA     nuclear telomere cap complex GO:0000783 ISS     fibrillar center GO:0001650 IDA     nucleus GO:0005634 IDA     nucleus GO:0005634 NAS     nucleoplasm GO:0005654 TAS     nucleolus GO:0005730 IDA     cytoplasm GO:0005737 IEA     spindle GO:0005819 IDA     spindle GO:0005819 IEA     nuclear body GO:0016604 IDA     shelterin complex GO:0070187 IDA     shelterin complex GO:0070187 IPI     shelterin complex GO:0070187 TAS