Gene description for NUDCD2
Gene name NudC domain containing 2
Gene symbol NUDCD2
Other names/aliases -
Species Homo sapiens
 Database cross references - NUDCD2
ExoCarta ExoCarta_134492
Entrez Gene 134492
HGNC 30535
UniProt Q8WVJ2  
 NUDCD2 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for NUDCD2
Molecular Function
    protein binding GO:0005515 IPI
Subcellular Localization
    intracellular GO:0005622 IDA
    condensed chromosome kinetochore GO:0000777 IEA
    microtubule organizing center GO:0005815 IEA
    spindle pole GO:0000922 IEA
    cytoplasm GO:0005737 IDA
    microtubule cytoskeleton GO:0015630 IDA
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified NUDCD2 in exosomes
1
Experiment ID 224
ISEV standards
EM|AFM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
CD63|CD81
EV Membrane markers
GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for NUDCD2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which NUDCD2 is involved
No pathways found





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