Gene description for PAFAH1B1
Gene name	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
Gene symbol	PAFAH1B1
Other names/aliases	LIS1 LIS2 MDCR MDS PAFAH
Species	Homo sapiens
Database cross references - PAFAH1B1
ExoCarta	ExoCarta_5048
Entrez Gene	5048
HGNC	8574
MIM	601545
UniProt	P43034
PAFAH1B1 identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Colorectal cancer cells	25890246
Colorectal cancer cells	25890246
Colorectal cancer cells	25890246
Endothelial cells	26027894
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927
Squamous carcinoma cells	20124223
Thymus	23844026
Urine	19056867

Gene ontology annotations for PAFAH1B1

Molecular Function     protein homodimerization activity GO:0042803 ISS     microtubule binding GO:0008017 ISS     phosphoprotein binding GO:0051219 ISS     protein binding GO:0005515 IPI     phospholipase binding GO:0043274 ISS     dynein intermediate chain binding GO:0045505 IEA     dynactin binding GO:0034452 ISS     dynein binding GO:0045502 IDA     heparin binding GO:0008201 ISS Biological Process     vesicle transport along microtubule GO:0047496 ISS     lipid catabolic process GO:0016042 IEA     mitotic cell cycle GO:0000278 TAS     actin cytoskeleton organization GO:0030036 ISS     neuromuscular process controlling balance GO:0050885 IMP     cerebral cortex development GO:0021987 IMP     microtubule cytoskeleton organization GO:0000226 ISS     negative regulation of neuron projection development GO:0010977 IEA     osteoclast development GO:0036035 IEA     layer formation in cerebral cortex GO:0021819 ISS     acrosome assembly GO:0001675 ISS     establishment of centrosome localization GO:0051660 IEA     transmission of nerve impulse GO:0019226 ISS     mitotic nuclear division GO:0007067 IEA     neuroblast proliferation GO:0007405 ISS     learning or memory GO:0007611 ISS     hippocampus development GO:0021766 ISS     positive regulation of cytokine-mediated signaling pathway GO:0001961 IEA     ameboidal-type cell migration GO:0001667 IEA     brain morphogenesis GO:0048854 IMP     nuclear migration GO:0007097 IEA     G2/M transition of mitotic cell cycle GO:0000086 TAS     cerebral cortex neuron differentiation GO:0021895 IEA     adult locomotory behavior GO:0008344 IMP     nuclear envelope disassembly GO:0051081 IEA     positive regulation of mitotic cell cycle GO:0045931 IEA     retrograde axon cargo transport GO:0008090 ISS     neuron migration GO:0001764 ISS     small GTPase mediated signal transduction GO:0007264 TAS     positive regulation of axon extension GO:0045773 IEA     corpus callosum morphogenesis GO:0021540 IMP     microtubule organizing center organization GO:0031023 IMP     protein secretion GO:0009306 IEA     establishment of mitotic spindle orientation GO:0000132 IMP     microtubule-based process GO:0007017 IDA     organelle organization GO:0006996 TAS     negative regulation of JNK cascade GO:0046329 IEA     platelet activating factor metabolic process GO:0046469 ISS     synaptic transmission GO:0007268 ISS     stem cell division GO:0017145 IEA Subcellular Localization     kinesin complex GO:0005871 IEA     axon GO:0030424 IEA     centrosome GO:0005813 ISS     nuclear envelope GO:0005635 IDA     growth cone GO:0030426 IEA     nuclear membrane GO:0031965 IEA     cell cortex GO:0005938 IDA     motile primary cilium GO:0031512 ISS     cytosol GO:0005829 TAS     perinuclear region of cytoplasm GO:0048471 ISS     microtubule associated complex GO:0005875 IDA     neuronal cell body GO:0043025 IEA     cell leading edge GO:0031252 ISS     astral microtubule GO:0000235 IDA     extracellular exosome GO:0070062 IDA     kinetochore GO:0000776 IDA