Gene description for DCTN1
Gene name	dynactin 1
Gene symbol	DCTN1
Other names/aliases	DAP-150 DP-150 P135
Species	Homo sapiens
Database cross references - DCTN1
ExoCarta	ExoCarta_1639
Entrez Gene	1639
HGNC	2711
MIM	601143
UniProt	Q14203
DCTN1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable
Neuroblastoma cells	25944692
Thymus	23844026

Gene ontology annotations for DCTN1

Molecular Function     dynein binding GO:0045502 IEA     protein binding GO:0005515 IPI     motor activity GO:0003774 IEA Biological Process     IRE1-mediated unfolded protein response GO:0036498 TAS     endoplasmic reticulum unfolded protein response GO:0030968 TAS     nervous system development GO:0007399 NAS     mitotic cell cycle GO:0000278 TAS     antigen processing and presentation of exogenous peptide antigen via MHC class II GO:0019886 TAS     organelle organization GO:0006996 TAS     cellular protein metabolic process GO:0044267 TAS     mitotic nuclear division GO:0007067 NAS     G2/M transition of mitotic cell cycle GO:0000086 TAS     melanosome transport GO:0032402 IEA     retrograde transport, endosome to Golgi GO:0042147 IMP     microtubule-based transport GO:0010970 IEA Subcellular Localization     microtubule GO:0005874 IDA     membrane GO:0016020 IDA     dynein complex GO:0030286 IEA     retromer complex GO:0030904 IDA     spindle pole GO:0000922 IDA     dynactin complex GO:0005869 IEA     cell leading edge GO:0031252 IEA     cytoplasm GO:0005737 TAS     cytosol GO:0005829 TAS     centrosome GO:0005813 IDA     kinetochore GO:0000776 IDA