Experiment description of studies that identified CEP350 in sEVs

1 Experiment ID 275 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81 Enriched markers ✔ AIF Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25844599     Organism Homo sapiens Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T." Journal name Oncotarget Publication year 2015 Sample Prostate cancer cells Sample name DU145 - Docetaxel sensitive Isolation/purification methods Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.12-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry/Flow cytometry/Western blotting

Protein-protein interactions for CEP350

Protein Interactor ExoCarta ID Identification method PubMed Species 1 Wdr48   Affinity Capture-MS Mus musculus 2 AP2B1 163 Proximity Label-MS Homo sapiens 3 RABL2B   Affinity Capture-MS Homo sapiens 4 Cep350   Affinity Capture-MS Mus musculus 5 SQSTM1 8878 Proximity Label-MS Homo sapiens 6 TPTE2   Proximity Label-MS Homo sapiens 7 BRCA1 672 Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 8 CAMSAP2   Proximity Label-MS Homo sapiens 9 EIF3B 8662 Cross-Linking-MS (XL-MS) Homo sapiens 10 Tubgcp6   Affinity Capture-MS Mus musculus 11 USP36   Affinity Capture-MS Homo sapiens 12 RNF10   Affinity Capture-MS Homo sapiens 13 CDC16 8881 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 14 PCNT   Proximity Label-MS Homo sapiens 15 KIF22   Affinity Capture-MS Homo sapiens 16 ACTR3 10096 Proximity Label-MS Homo sapiens 17 CCDC14   Proximity Label-MS Homo sapiens 18 Fgfr1op   Affinity Capture-MS Mus musculus Affinity Capture-MS Mus musculus 19 CCDC85A   Affinity Capture-MS Homo sapiens 20 Mib1   Affinity Capture-MS Mus musculus 21 Cep120   Affinity Capture-MS Mus musculus 22 Lrrcc1   Affinity Capture-MS Mus musculus 23 MAPK1 5594 Affinity Capture-MS Homo sapiens 24 PFN1 5216 Proximity Label-MS Homo sapiens 25 KRT8 3856 Proximity Label-MS Homo sapiens 26 S100A2 6273 Affinity Capture-MS Homo sapiens 27 HIST1H4A 8359 Cross-Linking-MS (XL-MS) Homo sapiens 28 MCC 4163 Affinity Capture-MS Homo sapiens 29 NR1H3   Reconstituted Complex Homo sapiens 30 MAPRE1 22919 Affinity Capture-MS Homo sapiens Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 31 OFD1 8481 Affinity Capture-MS Homo sapiens 32 CEP19   Affinity Capture-MS Homo sapiens 33 RPA2 6118 Proximity Label-MS Homo sapiens 34 VCP 7415 Affinity Capture-MS Homo sapiens 35 SLX4   Affinity Capture-MS Homo sapiens 36 PPARD   Reconstituted Complex Homo sapiens 37 PNMA2   Affinity Capture-MS Homo sapiens 38 PPP2CA 5515 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 39 KIF11 3832 Affinity Capture-MS Homo sapiens 40 KRT2 3849 Affinity Capture-MS Homo sapiens 41 APTX   Two-hybrid Homo sapiens 42 CYLD   Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 43 FGFR1OP   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 44 HIST1H2BH 8345 Cross-Linking-MS (XL-MS) Homo sapiens 45 Cep131   Affinity Capture-MS Mus musculus 46 Ppp2r1a 51792 Affinity Capture-MS Mus musculus 47 CDC14A   Proximity Label-MS Homo sapiens 48 DISC1 27185 Affinity Capture-MS Homo sapiens 49 HIST1H2BL 8340 Cross-Linking-MS (XL-MS) Homo sapiens 50 RNF40 9810 Affinity Capture-MS Homo sapiens 51 CEP135   Proximity Label-MS Homo sapiens 52 XPO1 7514 Affinity Capture-MS Homo sapiens 53 PIP 5304 Affinity Capture-MS Homo sapiens 54 EIF4G1 1981 Affinity Capture-MS Homo sapiens 55 PPARG 5468 Reconstituted Complex Homo sapiens 56 NR3C1 2908 Proximity Label-MS Homo sapiens 57 EPRS 2058 Cross-Linking-MS (XL-MS) Homo sapiens 58 DUSP16   Affinity Capture-MS Homo sapiens 59 NCKAP5   Affinity Capture-MS Homo sapiens 60 WEE1 7465 Affinity Capture-MS Homo sapiens 61 DCTN1 1639 Proximity Label-MS Homo sapiens 62 NXF1 10482 Affinity Capture-RNA Homo sapiens 63 CDK5RAP2 55755 Proximity Label-MS Homo sapiens 64 PCDH7 5099 Affinity Capture-MS Homo sapiens 65 MAPRE3   Proximity Label-MS Homo sapiens 66 KCNE3   Affinity Capture-MS Homo sapiens 67 Cep72   Affinity Capture-MS Mus musculus 68 PPP2R1A 5518 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 69 NIN 51199 Proximity Label-MS Homo sapiens 70 SLC3A2 6520 Cross-Linking-MS (XL-MS) Homo sapiens 71 PPARA   Reconstituted Complex Homo sapiens 72 GOLGA1   Proximity Label-MS Homo sapiens 73 Cep78   Affinity Capture-MS Mus musculus 74 NDC80 10403 Proximity Label-MS Homo sapiens 75 AMOT 154796 Proximity Label-MS Homo sapiens 76 PCM1 5108 Proximity Label-MS Homo sapiens 77 CTNNA1 1495 Proximity Label-MS Homo sapiens 78 KRT19 3880 Proximity Label-MS Homo sapiens 79 Prkar2a 19087 Affinity Capture-MS Mus musculus 80 STIL   Proximity Label-MS Homo sapiens 81 PPP2CB 5516 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 82 CCDC8   Affinity Capture-MS Homo sapiens 83 HIF1A 3091 Affinity Capture-MS Homo sapiens 84 SASS6 163786 Proximity Label-MS Homo sapiens 85 KRT18 3875 Proximity Label-MS Homo sapiens 86 PLEKHA5 54477 Two-hybrid Homo sapiens 87 HIST1H2BK 85236 Cross-Linking-MS (XL-MS) Homo sapiens 88 FBXL6   Proximity Label-MS Homo sapiens 89 TP53 7157 Affinity Capture-MS Homo sapiens 90 TRIM52   Affinity Capture-MS Homo sapiens 91 Cep135   Affinity Capture-MS Mus musculus 92 HIST1H2BC 8347 Cross-Linking-MS (XL-MS) Homo sapiens 93 SEPT10 151011 Proximity Label-MS Homo sapiens 94 DCTN2 10540 Proximity Label-MS Homo sapiens 95 RITA1   Affinity Capture-MS Homo sapiens 96 HIST1H2BD 3017 Cross-Linking-MS (XL-MS) Homo sapiens 97 KIFAP3 22920 Affinity Capture-MS Homo sapiens 98 CEP250 11190 Affinity Capture-MS Homo sapiens 99 LATS1   Proximity Label-MS Homo sapiens 100 ANAPC2 29882 Proximity Label-MS Homo sapiens 101 TRIM37   Proximity Label-MS Homo sapiens 102 KDM1A 23028 Proximity Label-MS Homo sapiens 103 PPP2R3C   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 104 PXN 5829 Proximity Label-MS Homo sapiens 105 CEP78 84131 Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 106 CCDC96   Affinity Capture-MS Homo sapiens 107 Pcm1   Affinity Capture-MS Mus musculus 108 ATOH1   Affinity Capture-MS Homo sapiens View the network

Pathways in which CEP350 is involved

No pathways found