Gene description for CEP350
Gene name centrosomal protein 350kDa
Gene symbol CEP350
Other names/aliases CAP350
GM133
Species Homo sapiens
 Database cross references - CEP350
ExoCarta ExoCarta_9857
Entrez Gene 9857
HGNC 24238
UniProt Q5VT06  
 CEP350 identified in exosomes derived from the following tissue/cell type
Prostate cancer cells 25844599    
 Gene ontology annotations for CEP350
Molecular Function
    protein binding GO:0005515 IPI
    microtubule binding GO:0008017 IEA
Biological Process
    microtubule anchoring GO:0034453 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    centrosome GO:0005813 IDA
    cytoplasm GO:0005737 IDA
    spindle GO:0005819 IEA
    membrane GO:0016020 IDA
 Experiment description of studies that identified CEP350 in exosomes
1
Experiment ID 275
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|RAB5A
EV Cytosolic markers
CD9|CD82|CD63|CD81
EV Membrane markers
AIF
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T.
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
 Protein-protein interactions for CEP350
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CEP350 is involved
No pathways found





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