Gene description for WEE1
Gene name	WEE1 G2 checkpoint kinase
Gene symbol	WEE1
Other names/aliases	WEE1A WEE1hu
Species	Homo sapiens
Database cross references - WEE1
ExoCarta	ExoCarta_7465
Vesiclepedia	VP_7465
Entrez Gene	7465
HGNC	12761
MIM	193525
UniProt	P30291
WEE1 identified in exosomes derived from the following tissue/cell type
Endothelial cells	26027894
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for WEE1

Molecular Function     magnesium ion binding GO:0000287 IEA     protein tyrosine kinase activity GO:0004713 IBA     protein tyrosine kinase activity GO:0004713 IDA     protein tyrosine kinase activity GO:0004713 TAS     non-membrane spanning protein tyrosine kinase activity GO:0004715 IEA     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     histone H3Y41 kinase activity GO:0035401 IEA     histone H2AXY142 kinase activity GO:0140801 IEA Biological Process     G2/M transition of mitotic cell cycle GO:0000086 TAS     microtubule cytoskeleton organization GO:0000226 IEA     chromatin remodeling GO:0006338 IEA     negative regulation of G2/M transition of mitotic cell cycle GO:0010972 IBA     negative regulation of G2/M transition of mitotic cell cycle GO:0010972 IDA     establishment of cell polarity GO:0030010 IEA     positive regulation of DNA replication GO:0045740 TAS     neuron projection morphogenesis GO:0048812 IEA     cell division GO:0051301 IEA     negative regulation of G1/S transition of mitotic cell cycle GO:2000134 TAS Subcellular Localization     nucleus GO:0005634 IBA     nucleus GO:0005634 IDA     nucleoplasm GO:0005654 TAS     nucleolus GO:0005730 IDA     cytoplasm GO:0005737 IBA