Gene description for CCNB1
Gene name	cyclin B1
Gene symbol	CCNB1
Other names/aliases	CCNB
Species	Homo sapiens
Database cross references - CCNB1
ExoCarta	ExoCarta_891
Entrez Gene	891
HGNC	1579
MIM	123836
UniProt	P14635
CCNB1 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for CCNB1

Molecular Function     histone kinase activity GO:0035173 IEA     patched binding GO:0005113 IPI     protein kinase binding GO:0019901 IPI     protein binding GO:0005515 IPI Biological Process     cell division GO:0051301 IEA     mitotic spindle stabilization GO:0043148 IMP     histone H3-S10 phosphorylation involved in chromosome condensation GO:2000775 IEA     regulation of chromosome condensation GO:0060623 IEA     response to drug GO:0042493 IEA     negative regulation of gene expression GO:0010629 IEA     mitotic metaphase plate congression GO:0007080 IMP     positive regulation of histone phosphorylation GO:0033129 IEA     in utero embryonic development GO:0001701 IEA     positive regulation of attachment of spindle microtubules to kinetochore GO:0051987 IMP     spermatogenesis GO:0007283 IEA     regulation of mitotic cell cycle spindle assembly checkpoint GO:0090266 IMP     oocyte maturation GO:0001556 IEA     positive regulation of mRNA 3'-end processing GO:0031442 IEA     cellular response to iron(III) ion GO:0071283 IEA     G1/S transition of mitotic cell cycle GO:0000082 TAS     anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 TAS     regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle GO:0051439 TAS     negative regulation of protein phosphorylation GO:0001933 IEA     regulation of cell cycle GO:0051726 TAS     tissue regeneration GO:0042246 IEA     digestive tract development GO:0048565 IEA     cellular response to fatty acid GO:0071398 IEA     ventricular cardiac muscle cell development GO:0055015 IEA     mitotic cell cycle GO:0000278 TAS     cellular response to hypoxia GO:0071456 IEA     positive regulation of cardiac muscle cell proliferation GO:0060045 IEA     protein complex assembly GO:0006461 IEA     response to DDT GO:0046680 IEA     cellular response to organic cyclic compound GO:0071407 IEA     G2/M transition of mitotic cell cycle GO:0000086 TAS     positive regulation of mitotic cell cycle GO:0045931 IMP     positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition GO:0051437 TAS     response to mechanical stimulus GO:0009612 IEA     mitotic nuclear envelope disassembly GO:0007077 TAS     positive regulation of fibroblast proliferation GO:0048146 IEA Subcellular Localization     centrosome GO:0005813 IDA     spindle pole GO:0000922 IDA     membrane GO:0016020 IEA     nucleoplasm GO:0005654 TAS     cytosol GO:0005829 TAS     cytoplasm GO:0005737 IDA     nucleus GO:0005634 IDA     condensed nuclear chromosome outer kinetochore GO:0000942 IDA