Gene description for Rpl4
Gene name ribosomal protein L4
Gene symbol Rpl4
Other names/aliases 2010004J23Rik
Species Mus musculus
 Database cross references - Rpl4
ExoCarta ExoCarta_67891
Entrez Gene 67891
UniProt Q9D8E6  
 Rpl4 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Rpl4
Molecular Function
    structural constituent of ribosome GO:0003735 IEA
    protein binding GO:0005515 IPI
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    translation GO:0006412 IEA
Subcellular Localization
    nucleolus GO:0005730 ISO
    focal adhesion GO:0005925 ISO
    extracellular exosome GO:0070062 ISO
    nucleus GO:0005634 ISO
    cytosolic large ribosomal subunit GO:0022625 ISO
    ribosome GO:0005840 IEA
    ribonucleoprotein complex GO:0030529 ISO
    membrane GO:0016020 ISO
    cytoplasm GO:0005737 ISO
    large ribosomal subunit GO:0015934 ISO
 Experiment description of studies that identified Rpl4 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Rpl4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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