Gene description for Rps19
Gene name ribosomal protein S19
Gene symbol Rps19
Other names/aliases Dsk3
Species Mus musculus
 Database cross references - Rps19
ExoCarta ExoCarta_20085
Entrez Gene 20085
UniProt Q9CZX8  
 Rps19 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Rps19
Molecular Function
    protein homodimerization activity GO:0042803 ISO
    structural constituent of ribosome GO:0003735 ISO
    fibroblast growth factor binding GO:0017134 ISO
    protein kinase binding GO:0019901 ISO
    translation initiation factor binding GO:0031369 ISO
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    Notch signaling pathway GO:0007219 IDA
    monocyte chemotaxis GO:0002548 ISO
    protein tetramerization GO:0051262 ISO
    nucleolus organization GO:0007000 ISO
    rRNA processing GO:0006364 ISO
    ribosomal small subunit biogenesis GO:0042274 ISO
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0000462 ISO
    negative regulation of respiratory burst involved in inflammatory response GO:0060266 ISO
    translation GO:0006412 IEA
    maturation of SSU-rRNA GO:0030490 ISO
    ribosomal small subunit assembly GO:0000028 ISO
    erythrocyte differentiation GO:0030218 ISO
    positive regulation of respiratory burst involved in inflammatory response GO:0060265 ISO
Subcellular Localization
    membrane GO:0016020 ISO
    cytoplasm GO:0005737 ISO
    nucleolus GO:0005730 ISO
    focal adhesion GO:0005925 ISO
    intracellular GO:0005622 IEA
    extracellular exosome GO:0070062 ISO
    ribosome GO:0005840 ISO
    ribonucleoprotein complex GO:0030529 IEA
    cytosolic small ribosomal subunit GO:0022627 ISO
    cytosol GO:0005829 ISO
 Experiment description of studies that identified Rps19 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Rps19
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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