ExoCarta: Gene summary

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Gene description for Rps17
Gene name	ribosomal protein S17
Gene symbol	Rps17
Other names/aliases	-
Species	Mus musculus
Database cross references - Rps17
ExoCarta	ExoCarta_20068
Entrez Gene	20068
UniProt	P63276
Rps17 identified in exosomes derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Rps17

Molecular Function
	poly(A) RNA binding	GO:0044822	ISO
	structural constituent of ribosome	GO:0003735	ISO
Biological Process
	erythrocyte homeostasis	GO:0034101	ISO
	rRNA processing	GO:0006364	ISO
	ribosomal small subunit assembly	GO:0000028	IBA
	ribosomal small subunit biogenesis	GO:0042274	ISO
	translation	GO:0006412	ISO
Subcellular Localization
	cytosolic small ribosomal subunit	GO:0022627	ISO
	membrane	GO:0016020	ISO
	ribonucleoprotein complex	GO:0030529	IEA
	focal adhesion	GO:0005925	ISO
	ribosome	GO:0005840	IEA
	intracellular	GO:0005622	IEA
	extracellular exosome	GO:0070062	ISO

Experiment description of studies that identified Rps17 in exosomes

Experiment ID

ISEV standards
✔ EM	EV Biophysical techniques
✘	EV Cytosolic markers
✔ CD63	EV Membrane markers
✘	EV Negative markers
✘	EV Particle analysis

Identified molecule

protein

Identification method

Mass spectrometry

PubMed ID

17486113

Organism

Mus musculus
Homo sapiens

Experiment description

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.

Authors

Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO

Journal name

NCB

Publication year

2007

Sample

Mast cells

Sample name

MC9
Bone marrow-derived mast cells
HMC-1

Isolation/purification methods

Filtration
Ultracentrifugation
Sucrose density gradient

Flotation density

1.11-1.21 g/mL

Molecules identified in the study

Protein
mRNA
miRNA

Methods used in the study

Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array