Gene description for Rps2
Gene name ribosomal protein S2
Gene symbol Rps2
Other names/aliases Llrep3
S4
Species Mus musculus
 Database cross references - Rps2
ExoCarta ExoCarta_16898
Entrez Gene 16898
UniProt P25444  
 Rps2 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
Pancreatic cells 19351151    
 Gene ontology annotations for Rps2
Molecular Function
    fibroblast growth factor binding GO:0017134 ISO
    poly(A) RNA binding GO:0044822 ISO
    protein complex binding GO:0032403 ISO
    enzyme binding GO:0019899 ISO
    mRNA binding GO:0003729 ISO
    RNA binding GO:0003723 IEA
    structural constituent of ribosome GO:0003735 ISO
Biological Process
    cellular response to interleukin-4 GO:0071353 IDA
    formation of translation preinitiation complex GO:0001731 ISO
    ribosomal small subunit assembly GO:0000028 ISO
    positive regulation of transferase activity GO:0051347 ISO
    translation GO:0006412 IEA
Subcellular Localization
    ribosome GO:0005840 IEA
    small ribosomal subunit GO:0015935 IEA
    nucleoplasm GO:0005654 ISO
    nucleus GO:0005634 ISO
    extracellular exosome GO:0070062 ISO
    focal adhesion GO:0005925 ISO
    membrane GO:0016020 ISO
    cytoplasm GO:0005737 ISO
    cytosolic small ribosomal subunit GO:0022627 ISO
    ribonucleoprotein complex GO:0030529 ISO
 Experiment description of studies that identified Rps2 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
2
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
3
Experiment ID 188
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH|UCHL1|HSP90
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Rps2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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