ExoCarta: Gene summary

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Gene description for Rps23
Gene name	ribosomal protein S23
Gene symbol	Rps23
Other names/aliases	2410044J15Rik
Species	Mus musculus
Database cross references - Rps23
ExoCarta	ExoCarta_66475
Entrez Gene	66475
UniProt	P62267
Rps23 identified in exosomes derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Rps23

Molecular Function
	structural constituent of ribosome	GO:0003735	IEA
	poly(A) RNA binding	GO:0044822	ISO
Biological Process
	translation	GO:0006412	IEA
Subcellular Localization
	intracellular	GO:0005622	IEA
	small ribosomal subunit	GO:0015935	IEA
	membrane	GO:0016020	ISO
	ribosome	GO:0005840	IEA
	nucleolus	GO:0005730	ISO
	cytosolic small ribosomal subunit	GO:0022627	ISO
	ribonucleoprotein complex	GO:0030529	IEA
	cytoplasm	GO:0005737	ISO

Experiment description of studies that identified Rps23 in exosomes

Experiment ID

ISEV standards
✔ EM	EV Biophysical techniques
✘	EV Cytosolic markers
✔ CD63	EV Membrane markers
✘	EV Negative markers
✘	EV Particle analysis

Identified molecule

protein

Identification method

Mass spectrometry

PubMed ID

17486113

Organism

Mus musculus
Homo sapiens

Experiment description

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.

Authors

Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO

Journal name

NCB

Publication year

2007

Sample

Mast cells

Sample name

MC9
Bone marrow-derived mast cells
HMC-1

Isolation/purification methods

Filtration
Ultracentrifugation
Sucrose density gradient

Flotation density

1.11-1.21 g/mL

Molecules identified in the study

Protein
mRNA
miRNA

Methods used in the study

Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array