Gene description for Rpl28
Gene name ribosomal protein L28
Gene symbol Rpl28
Other names/aliases D7Wsu21e
Species Mus musculus
 Database cross references - Rpl28
ExoCarta ExoCarta_19943
Entrez Gene 19943
UniProt P41105  
 Rpl28 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Rpl28
Molecular Function
    structural constituent of ribosome GO:0003735 IEA
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    positive regulation of protein targeting to mitochondrion GO:1903955 ISO
    regulation of mitochondrion degradation GO:1903146 ISO
    translation GO:0006412 IEA
Subcellular Localization
    cell body GO:0044297 ISO
    cytoplasm GO:0005737 ISO
    dendrite GO:0030425 ISO
    ribonucleoprotein complex GO:0030529 IEA
    ribosome GO:0005840 IEA
    intracellular GO:0005622 IEA
    cytoplasmic ribonucleoprotein granule GO:0036464 ISO
    cytosolic large ribosomal subunit GO:0022625 ISO
    extracellular exosome GO:0070062 ISO
    membrane GO:0016020 ISO
 Experiment description of studies that identified Rpl28 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Rpl28
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Rpl28 is involved
No pathways found





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