Gene description for Rpl8
Gene name ribosomal protein L8
Gene symbol Rpl8
Other names/aliases -
Species Mus musculus
 Database cross references - Rpl8
ExoCarta ExoCarta_26961
Entrez Gene 26961
UniProt P62918  
 Rpl8 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Rpl8
Molecular Function
    rRNA binding GO:0019843 IEA
    poly(A) RNA binding GO:0044822 ISO
    RNA binding GO:0003723 IEA
    protein binding GO:0005515 IPI
    structural constituent of ribosome GO:0003735 IEA
Biological Process
    translation GO:0006412 IEA
Subcellular Localization
    ribonucleoprotein complex GO:0030529 IEA
    membrane GO:0016020 ISO
    nucleolus GO:0005730 ISO
    intracellular GO:0005622 IEA
    large ribosomal subunit GO:0015934 IEA
    cytoplasm GO:0005737 ISO
    cytosolic large ribosomal subunit GO:0022625 ISO
    ribosome GO:0005840 IEA
    focal adhesion GO:0005925 ISO
 Experiment description of studies that identified Rpl8 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Rpl8
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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