Gene description for Pa2g4 |
Gene name |
proliferation-associated 2G4 |
Gene symbol |
Pa2g4 |
Other names/aliases |
38kDa AA672939 Ebp1 Plfap |
Species |
Mus musculus |
Database cross references - Pa2g4 |
ExoCarta |
ExoCarta_18813 |
Vesiclepedia |
VP_18813 |
Entrez Gene |
18813 |
UniProt |
P50580
|
Pa2g4 identified in exosomes derived from the following tissue/cell type |
Colon cancer cells
|
37309723
|
Neural stem cells
|
25242146
|
T-cell lymphoma cells
|
37309723
|
Gene ontology annotations for Pa2g4 |
|
Experiment description of studies that identified Pa2g4 in exosomes |
1 |
Experiment ID |
907 |
MISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
|
EV Enriched markers |
✔
HSPA5
|
EV Negative markers |
✔
NTA
|
EV Particle analysis
|
|
Identified molecule |
Protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
37309723
|
Organism |
Mus musculus |
Experiment description |
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells |
Authors |
Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S. |
Journal name |
Proteomics
|
Publication year |
2023 |
Sample |
Colon cancer cells |
Sample name |
C26 |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Western blotting Mass spectrometry |
|
|
2 |
Experiment ID |
264 |
MISEV standards |
✘
|
EV Biophysical techniques |
✔
CD63|CD9
|
EV Enriched markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
25242146
|
Organism |
Mus musculus |
Experiment description |
Extracellular Vesicles from Neural Stem Cells Transfer IFN-γ via Ifngr1 to Activate Stat1 Signaling in Target Cells |
Authors |
Chiara Cossetti, Nunzio Iraci, Tim R. Mercer, Tommaso Leonardi, Emanuele Alpi, Denise Drago, Clara Alfaro-Cervello, Harpreet K. Saini, Matthew P. Davis, Julia Schaeffer, Beatriz Vega, Matilde Stefanini, CongJian Zhao, Werner Muller, Jose Manuel Garcia-Verdugo, Suresh Mathivanan, Angela Bachi, Anton J. Enright, John S. Mattick, Stefano Pluchino |
Journal name |
Molecular Cell
|
Publication year |
2014 |
Sample |
Neural stem cells |
Sample name |
NPCs - Th2 treated |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation Sucrose density gradient |
Flotation density |
1.13-1.20 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Western blotting Mass spectrometry |
|
|
3 |
Experiment ID |
908 |
MISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
|
EV Enriched markers |
✔
HSPA5
|
EV Negative markers |
✔
NTA
|
EV Particle analysis
|
|
Identified molecule |
Protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
37309723
|
Organism |
Mus musculus |
Experiment description |
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells |
Authors |
Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S. |
Journal name |
Proteomics
|
Publication year |
2023 |
Sample |
T-cell lymphoma cells |
Sample name |
EL4 |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Western blotting Mass spectrometry |
|
|
Protein-protein interactions for Pa2g4 |
|
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
No interactions are found.
|
|
Pathways in which Pa2g4 is involved |
No pathways found
|
|
|