Gene description for Rpl3
Gene name ribosomal protein L3
Gene symbol Rpl3
Other names/aliases F2
J1
Species Mus musculus
 Database cross references - Rpl3
ExoCarta ExoCarta_27367
Entrez Gene 27367
UniProt P27659  
 Rpl3 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Rpl3
Molecular Function
    structural constituent of ribosome GO:0003735 IEA
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    translation GO:0006412 IEA
    cellular response to interleukin-4 GO:0071353 IDA
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    nucleolus GO:0005730 ISO
    nucleus GO:0005634 ISO
    ribonucleoprotein complex GO:0030529 IEA
    intracellular GO:0005622 IEA
    ribosome GO:0005840 IEA
    cytoplasm GO:0005737 ISO
    cytosolic large ribosomal subunit GO:0022625 ISO
    nucleoplasm GO:0005654 ISO
    focal adhesion GO:0005925 ISO
 Experiment description of studies that identified Rpl3 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Rpl3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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