Gene description for Pgk2
Gene name phosphoglycerate kinase 2
Gene symbol Pgk2
Other names/aliases Pgk-2
Tcp-2
Species Mus musculus
 Database cross references - Pgk2
ExoCarta ExoCarta_18663
Entrez Gene 18663
UniProt P09041  
 Pgk2 identified in exosomes derived from the following tissue/cell type
Oligodendrocytes 21136642    
 Gene ontology annotations for Pgk2
Molecular Function
    ATP binding GO:0005524 IEA
    kinase activity GO:0016301 IEA
    transferase activity GO:0016740 IEA
    phosphoglycerate kinase activity GO:0004618 IMP
    nucleotide binding GO:0000166 IEA
Biological Process
    glycolytic process GO:0006096 IMP
    phosphorylation GO:0016310 IMP
    activation of mitophagy in response to mitochondrial depolarization GO:0098779 ISO
    sperm motility GO:0030317 IMP
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    sperm fibrous sheath GO:0035686 IDA
    cilium GO:0005929 IDA
    nucleus GO:0005634 ISO
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified Pgk2 in exosomes
1
Experiment ID 33
ISEV standards
EM|IEM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21136642    
Organism Mus musculus
Experiment description Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
Authors Kramer-Albers EM, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, Nave KA, Schild H, Trotter J
Journal name PROTEOMICS_CL
Publication year 2007
Sample Oligodendrocytes
Sample name Oligodendrocytes
Oli-neu
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Pgk2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pgk2 is involved
No pathways found





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