Gene description for Snd1
Gene name staphylococcal nuclease and tudor domain containing 1
Gene symbol Snd1
Other names/aliases AL033314
Tudor-SN
Species Mus musculus
 Database cross references - Snd1
ExoCarta ExoCarta_56463
Entrez Gene 56463
UniProt Q78PY7  
 Snd1 identified in exosomes derived from the following tissue/cell type
Neural stem cells 25242146    
 Gene ontology annotations for Snd1
Molecular Function
    protein binding GO:0005515 IPI
    nuclease activity GO:0004518 IEA
    nucleic acid binding GO:0003676 IEA
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    regulation of transcription, DNA-templated GO:0006355 IEA
    osteoblast differentiation GO:0001649 ISO
    transcription, DNA-templated GO:0006351 IEA
    gene silencing by RNA GO:0031047 IEA
Subcellular Localization
    RISC complex GO:0016442 IEA
    membrane GO:0016020 ISO
    nucleus GO:0005634 IDA
    mitochondrion GO:0005739 IDA
    dense body GO:0097433 IDA
    cytoplasm GO:0005737 ISO
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Snd1 in exosomes
1
Experiment ID 263
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
CD63|CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25242146    
Organism Mus musculus
Experiment description Extracellular Vesicles from Neural Stem Cells Transfer IFN-γ via Ifngr1 to Activate Stat1 Signaling in Target Cells
Authors Chiara Cossetti, Nunzio Iraci, Tim R. Mercer, Tommaso Leonardi, Emanuele Alpi, Denise Drago, Clara Alfaro-Cervello, Harpreet K. Saini, Matthew P. Davis, Julia Schaeffer, Beatriz Vega, Matilde Stefanini, CongJian Zhao, Werner Muller, Jose Manuel Garcia-Verdugo, Suresh Mathivanan, Angela Bachi, Anton J. Enright, John S. Mattick, Stefano Pluchino
Journal name Molecular Cell
Publication year 2014
Sample Neural stem cells
Sample name NPCs - Th1 treated
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Snd1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Snd1 is involved
No pathways found





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