Gene description for Rpl13a
Gene name ribosomal protein L13A
Gene symbol Rpl13a
Other names/aliases 1810026N22Rik
Tstap198-7
tum-antigen
Species Mus musculus
 Database cross references - Rpl13a
ExoCarta ExoCarta_22121
Entrez Gene 22121
UniProt P19253  
 Rpl13a identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
Neural stem cells 25242146    
 Gene ontology annotations for Rpl13a
Molecular Function
    mRNA binding GO:0003729 IDA
    poly(A) RNA binding GO:0044822 ISO
    structural constituent of ribosome GO:0003735 IEA
Biological Process
    macrophage chemotaxis GO:0048246 IMP
    cellular response to interferon-gamma GO:0071346 ISO
    negative regulation of formation of translation preinitiation complex GO:1901194 ISO
    lung morphogenesis GO:0060425 IMP
    regulation of translation GO:0006417 IEA
    response to lipopolysaccharide GO:0032496 IMP
    negative regulation of translation GO:0017148 ISO
    translation GO:0006412 IEA
    regulation of homeostatic process GO:0032844 IMP
Subcellular Localization
    ribonucleoprotein complex GO:0030529 ISO
    large ribosomal subunit GO:0015934 IEA
    cytoplasm GO:0005737 ISO
    GAIT complex GO:0097452 IDA
    nucleolus GO:0005730 ISO
    focal adhesion GO:0005925 ISO
    membrane GO:0016020 ISO
    nucleus GO:0005634 ISO
    cytosolic large ribosomal subunit GO:0022625 ISO
    ribosome GO:0005840 IEA
 Experiment description of studies that identified Rpl13a in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
2
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
3
Experiment ID 263
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63|CD9
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25242146    
Organism Mus musculus
Experiment description Extracellular Vesicles from Neural Stem Cells Transfer IFN-γ via Ifngr1 to Activate Stat1 Signaling in Target Cells
Authors Chiara Cossetti, Nunzio Iraci, Tim R. Mercer, Tommaso Leonardi, Emanuele Alpi, Denise Drago, Clara Alfaro-Cervello, Harpreet K. Saini, Matthew P. Davis, Julia Schaeffer, Beatriz Vega, Matilde Stefanini, CongJian Zhao, Werner Muller, Jose Manuel Garcia-Verdugo, Suresh Mathivanan, Angela Bachi, Anton J. Enright, John S. Mattick, Stefano Pluchino
Journal name Molecular Cell
Publication year 2014
Sample Neural stem cells
Sample name NPCs - Th1 treated
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Rpl13a
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here