Experiment description of studies that identified Syncrip in sEVs

1 Experiment ID 907 MISEV standards ✔ EM Biophysical techniques ✔ Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a Enriched markers ✔ HSPA5 Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 37309723     Organism Mus musculus Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S." Journal name Proteomics Publication year 2023 Sample Colon cancer cells Sample name C26 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 908 MISEV standards ✔ EM Biophysical techniques ✔ Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a Enriched markers ✔ HSPA5 Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 37309723     Organism Mus musculus Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S." Journal name Proteomics Publication year 2023 Sample T-cell lymphoma cells Sample name EL4 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for Syncrip

Protein Interactor ExoCarta ID Identification method PubMed Species 1 Sf3a3 75062 Co-fractionation Mus musculus 2 Ddx5 13207 Co-fractionation Mus musculus 3 Kctd13   Affinity Capture-MS Mus musculus 4 Rps3 27050 Co-fractionation Mus musculus 5 Rplp0 11837 Co-fractionation Mus musculus 6 Ncbp1 433702 Co-fractionation Mus musculus 7 Fmr1   Co-fractionation Mus musculus 8 Snrnp200 320632 Co-fractionation Mus musculus 9 Fancd2   Affinity Capture-MS Mus musculus 10 MKRN1 23608 Affinity Capture-MS Homo sapiens 11 Rpl13a 22121 Co-fractionation Mus musculus 12 Atxn2 20239 Co-fractionation Mus musculus 13 Fitm2   Negative Genetic Mus musculus 14 Hspa8 15481 Co-fractionation Mus musculus 15 Snrpd1 20641 Co-fractionation Mus musculus 16 Srrm1 51796 Co-fractionation Mus musculus 17 Prpf8 192159 Co-fractionation Mus musculus 18 Sra1   Co-fractionation Mus musculus 19 Rps4x 20102 Co-fractionation Mus musculus 20 Cdc5l 71702 Co-fractionation Mus musculus 21 Trove2 20822 Co-fractionation Mus musculus 22 Gapdh 14433 Co-fractionation Mus musculus 23 Rps8 20116 Co-fractionation Mus musculus 24 Alyref   Co-fractionation Mus musculus 25 2700060E02Rik 68045 Co-fractionation Mus musculus 26 Snrpd2 107686 Co-fractionation Mus musculus 27 Atxn1   Affinity Capture-MS Mus musculus 28 Fzr1   Affinity Capture-MS Mus musculus 29 Iqgap1 29875 Co-fractionation Mus musculus 30 Tfe3   Affinity Capture-MS Mus musculus 31 Cul3   Affinity Capture-MS Mus musculus 32 Frg1   Co-fractionation Mus musculus 33 Rpl24 68193 Co-fractionation Mus musculus 34 Sf3a1 67465 Co-fractionation Mus musculus 35 Rps6 20104 Co-fractionation Mus musculus 36 Ncl 17975 Co-fractionation Mus musculus 37 Actb 11461 Co-fractionation Mus musculus 38 Ppwd1   Co-fractionation Mus musculus 39 Psmd7 17463 Co-fractionation Mus musculus 40 Snrpd3 67332 Co-fractionation Mus musculus 41 Sf3b3 101943 Co-fractionation Mus musculus 42 Mettl21e   Affinity Capture-MS Mus musculus 43 Hnrnph1 59013 Co-fractionation Mus musculus 44 Lsm3   Co-fractionation Mus musculus 45 Hnrnpd 11991 Co-fractionation Mus musculus 46 Ybx1 22608 Co-fractionation Mus musculus 47 Pabpc1 18458 Co-fractionation Mus musculus 48 Srsf1 110809 Co-fractionation Mus musculus 49 Zbtb7b   Affinity Capture-MS Mus musculus 50 Prmt8   Co-fractionation Mus musculus 51 Rps9 76846 Co-fractionation Mus musculus 52 Hnrnpc 15381 Co-fractionation Mus musculus 53 Actn4 60595 Co-fractionation Mus musculus 54 Srrm2   Co-fractionation Mus musculus 55 Fkbp3   Co-fractionation Mus musculus 56 Snw1   Co-fractionation Mus musculus 57 Rps3a1 20091 Co-fractionation Mus musculus 58 Pabpn1 54196 Co-fractionation Mus musculus 59 Ago2 239528 Co-fractionation Mus musculus 60 Rpl26 19941 Co-fractionation Mus musculus 61 Hnrnpa2b1 53379 Co-fractionation Mus musculus 62 Dhx9 13211 Co-fractionation Mus musculus 63 Sf3b1 81898 Co-fractionation Mus musculus 64 Hnrnpk 15387 Co-fractionation Mus musculus 65 Ppil3   Co-fractionation Mus musculus 66 Nlrp3   Affinity Capture-MS Mus musculus 67 Eed   Affinity Capture-MS Mus musculus 68 Cwc27   Co-fractionation Mus musculus 69 Mapt   Affinity Capture-MS Mus musculus 70 Tia1   Affinity Capture-MS Mus musculus 71 Skiv2l2   Co-fractionation Mus musculus 72 Stau1   Co-fractionation Mus musculus 73 Eftud2 20624 Co-fractionation Mus musculus View the network

Pathways in which Syncrip is involved

No pathways found