Gene description for Iqgap1
Gene name	IQ motif containing GTPase activating protein 1
Gene symbol	Iqgap1
Other names/aliases	AA682088 D7Ertd237e D7Ertd257e mKIAA0051
Species	Mus musculus
Database cross references - Iqgap1
ExoCarta	ExoCarta_29875
Entrez Gene	29875
UniProt	Q9JKF1
Iqgap1 identified in exosomes derived from the following tissue/cell type
Macrophages	23658846
Macrophages	23658846
Macrophages	23658846
Mast cells	17486113
Microglia	16081791
Pancreatic cells	19351151

Gene ontology annotations for Iqgap1

Molecular Function     protein serine/threonine kinase activator activity GO:0043539 ISO     protein binding GO:0005515 IPI     Rac GTPase binding GO:0048365 IPI     protein complex binding GO:0032403 ISO     Rho GTPase binding GO:0017048 IPI     calmodulin binding GO:0005516 ISO     GTPase activator activity GO:0005096 IEA     protein kinase binding GO:0019901 ISO     protein phosphatase binding GO:0019903 ISO     phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 ISO Biological Process     cellular response to epidermal growth factor stimulus GO:0071364 ISO     cellular response to fibroblast growth factor stimulus GO:0044344 IMP     fibroblast growth factor receptor signaling pathway GO:0008543 IMP     platelet-derived growth factor receptor signaling pathway GO:0048008 IMP     cellular response to calcium ion GO:0071277 ISO     negative regulation of dephosphorylation GO:0035305 IGI     small GTPase mediated signal transduction GO:0007264 IEA     regulation of GTPase activity GO:0043087 IEA     cellular response to platelet-derived growth factor stimulus GO:0036120 IMP     positive regulation of protein kinase activity GO:0045860 ISO     signal transduction GO:0007165 IEA     epidermal growth factor receptor signaling pathway GO:0007173 ISO     neuron projection extension GO:1990138 ISO     regulation of cytokine production GO:0001817 IMP     positive regulation of protein serine/threonine kinase activity GO:0071902 ISO Subcellular Localization     axon GO:0030424 ISO     cytoplasm GO:0005737 ISO     growth cone GO:0030426 ISO     neuron projection GO:0043005 ISO     cell leading edge GO:0031252 IGI     extracellular exosome GO:0070062 ISO     microtubule cytoskeleton GO:0015630 ISO     cytoplasmic ribonucleoprotein granule GO:0036464 ISO     cell junction GO:0030054 ISO     membrane GO:0016020 IDA     extrinsic component of cytoplasmic side of plasma membrane GO:0031234 ISO     lateral plasma membrane GO:0016328 IDA     ribonucleoprotein complex GO:0030529 IGI     nucleoplasm GO:0005654 ISO     midbody GO:0030496 ISO     protein complex GO:0043234 ISO     actin cytoskeleton GO:0015629 ISO     plasma membrane GO:0005886 ISO     focal adhesion GO:0005925 ISO     cell-cell junction GO:0005911 IDA     microtubule GO:0005874 ISO