Gene description for Eif4g1
Gene name eukaryotic translation initiation factor 4, gamma 1
Gene symbol Eif4g1
Other names/aliases E030015G23Rik
eIF-4-gamma 1
eIF-4G 1
Species Mus musculus
 Database cross references - Eif4g1
ExoCarta ExoCarta_208643
Entrez Gene 208643
UniProt Q6NZJ6  
 Eif4g1 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Eif4g1
Molecular Function
    poly(A) RNA binding GO:0044822 ISO
    translation initiation factor activity GO:0003743 IEA
    eukaryotic initiation factor 4E binding GO:0008190 ISO
    RNA binding GO:0003723 IEA
    protein binding GO:0005515 IPI
Biological Process
    regulation of translational initiation GO:0006446 ISO
    regulation of translation GO:0006417 IEA
    translation GO:0006412 IEA
    behavioral fear response GO:0001662 IGI
    positive regulation of neuron differentiation GO:0045666 IMP
    translational initiation GO:0006413 IEA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    eukaryotic translation initiation factor 4F complex GO:0016281 ISO
    membrane GO:0016020 ISO
 Experiment description of studies that identified Eif4g1 in exosomes
Experiment ID 188
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Eif4g1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.

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