Gene description for Hnrnpc
Gene name heterogeneous nuclear ribonucleoprotein C
Gene symbol Hnrnpc
Other names/aliases AL022939
Species Mus musculus
 Database cross references - Hnrnpc
ExoCarta ExoCarta_15381
Entrez Gene 15381
UniProt Q9Z204  
 Hnrnpc identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Hnrnpc
Molecular Function
    nucleic acid binding GO:0003676 IEA
    RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000978 ISO
    RNA binding GO:0003723 IEA
    identical protein binding GO:0042802 ISO
    nucleosomal DNA binding GO:0031492 ISO
    nucleotide binding GO:0000166 IEA
    poly(U) RNA binding GO:0008266 ISO
    N6-methyladenosine-containing RNA binding GO:1990247 ISO
    mRNA binding GO:0003729 IDA
    poly(A) RNA binding GO:0044822 ISO
    RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980 ISO
    mRNA 3'-UTR binding GO:0003730 ISO
Biological Process
    mRNA processing GO:0006397 IEA
    ATP-dependent chromatin remodeling GO:0043044 ISO
    mRNA splicing, via spliceosome GO:0000398 ISO
    RNA splicing GO:0008380 IEA
    osteoblast differentiation GO:0001649 ISO
    3'-UTR-mediated mRNA stabilization GO:0070935 ISO
Subcellular Localization
    catalytic step 2 spliceosome GO:0071013 ISO
    spliceosomal complex GO:0005681 ISO
    nucleus GO:0005634 ISO
    ribonucleoprotein complex GO:0030529 IEA
    protein complex GO:0043234 ISO
    extracellular exosome GO:0070062 ISO
    membrane GO:0016020 ISO
    cytosol GO:0005829 ISO
    nucleoplasm GO:0005654 ISO
    pronucleus GO:0045120 IDA
    nuclear chromatin GO:0000790 ISO
 Experiment description of studies that identified Hnrnpc in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Hnrnpc
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Hnrnpc is involved
mRNA Splicing - Major Pathway IEA Reactome
Processing of Capped Intron-Containing Pre-mRNA IEA Reactome

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