Gene description for Hnrnpa2b1
Gene name heterogeneous nuclear ribonucleoprotein A2/B1
Gene symbol Hnrnpa2b1
Other names/aliases 9130414A06Rik
Hnrpa2
Hnrpa2b1
hnrnp-A
Species Mus musculus
 Database cross references - Hnrnpa2b1
ExoCarta ExoCarta_53379
Entrez Gene 53379
UniProt O88569  
 Hnrnpa2b1 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Hnrnpa2b1
Molecular Function
    regulatory region RNA binding GO:0001069 ISO
    single-stranded telomeric DNA binding GO:0043047 ISO
    nucleic acid binding GO:0003676 IEA
    poly(A) RNA binding GO:0044822 ISO
    pre-mRNA intronic binding GO:0097157 IDA
    nucleotide binding GO:0000166 IEA
    RNA binding GO:0003723 ISO
Biological Process
    RNA splicing GO:0008380 IEA
    RNA transport GO:0050658 ISO
    mRNA processing GO:0006397 ISO
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 IGI
    negative regulation of mRNA splicing, via spliceosome GO:0048025 IMP
Subcellular Localization
    neuron projection GO:0043005 ISO
    cytoplasm GO:0005737 ISO
    neuronal cell body GO:0043025 ISO
    chromatin GO:0000785 ISO
    neuronal ribonucleoprotein granule GO:0071598 ISO
    spliceosomal complex GO:0005681 ISO
    nucleus GO:0005634 ISO
    perikaryon GO:0043204 ISO
    ribonucleoprotein complex GO:0030529 ISO
    membrane GO:0016020 ISO
    catalytic step 2 spliceosome GO:0071013 ISO
 Experiment description of studies that identified Hnrnpa2b1 in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Hnrnpa2b1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Hnrnpa2b1 is involved
PathwayEvidenceSource
mRNA Splicing - Major Pathway IEA Reactome
Processing of Capped Intron-Containing Pre-mRNA IEA Reactome





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