Gene description for Snrpd1
Gene name small nuclear ribonucleoprotein D1
Gene symbol Snrpd1
Other names/aliases AA407109
AL023031
SMD1
Species Mus musculus
 Database cross references - Snrpd1
ExoCarta ExoCarta_20641
Vesiclepedia VP_20641
Entrez Gene 20641
UniProt P62315  
 Snrpd1 identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Snrpd1
Molecular Function
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    spliceosomal snRNP assembly GO:0000387 ISO
    mRNA processing GO:0006397 IEA
    RNA splicing GO:0008380 IEA
    positive regulation of defense response to virus by host GO:0002230 ISO
    activation of mitophagy in response to mitochondrial depolarization GO:0098779 ISO
Subcellular Localization
    U4 snRNP GO:0005687 ISO
    methylosome GO:0034709 ISO
    U1 snRNP GO:0005685 ISO
    spliceosomal complex GO:0005681 IEA
    nucleus GO:0005634 ISO
    catalytic step 2 spliceosome GO:0071013 ISO
    cytoplasm GO:0005737 IDA
    SMN-Sm protein complex GO:0034719 ISO
    U12-type spliceosomal complex GO:0005689 ISO
    pICln-Sm protein complex GO:0034715 ISO
    cytosol GO:0005829 ISO
    ribonucleoprotein complex GO:0030529 IEA
 Experiment description of studies that identified Snrpd1 in exosomes
1
Experiment ID 907
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Snrpd1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Snrpd1 is involved
PathwayEvidenceSource
mRNA Splicing - Major Pathway IEA Reactome
mRNA Splicing - Minor Pathway IEA Reactome
snRNP Assembly IEA Reactome





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