Gene description for Snrpd3
Gene name small nuclear ribonucleoprotein D3
Gene symbol Snrpd3
Other names/aliases 1700043E15Rik
2310009E13Rik
AW046420
SMD3
Species Mus musculus
 Database cross references - Snrpd3
ExoCarta ExoCarta_67332
Entrez Gene 67332
UniProt P62320  
 Snrpd3 identified in exosomes derived from the following tissue/cell type
Neural stem cells 25242146    
 Gene ontology annotations for Snrpd3
Molecular Function
    enzyme binding GO:0019899 ISO
    RNA binding GO:0003723 IEA
    histone pre-mRNA DCP binding GO:0071208 IDA
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    mRNA processing GO:0006397 IEA
    RNA splicing GO:0008380 IEA
    spliceosomal snRNP assembly GO:0000387 ISO
    protein methylation GO:0006479 ISO
Subcellular Localization
    U12-type spliceosomal complex GO:0005689 ISO
    nucleus GO:0005634 IDA
    SMN-Sm protein complex GO:0034719 ISO
    U7 snRNP GO:0005683 ISO
    cytoplasm GO:0005737 ISO
    ribonucleoprotein complex GO:0030529 IEA
    cytosol GO:0005829 ISO
    U4 snRNP GO:0005687 ISO
    spliceosomal complex GO:0005681 IEA
    methylosome GO:0034709 ISO
    nucleoplasm GO:0005654 ISO
    catalytic step 2 spliceosome GO:0071013 ISO
    extracellular exosome GO:0070062 ISO
    U1 snRNP GO:0005685 ISO
    pICln-Sm protein complex GO:0034715 ISO
 Experiment description of studies that identified Snrpd3 in exosomes
1
Experiment ID 263
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63|CD9
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25242146    
Organism Mus musculus
Experiment description Extracellular Vesicles from Neural Stem Cells Transfer IFN-γ via Ifngr1 to Activate Stat1 Signaling in Target Cells
Authors Chiara Cossetti, Nunzio Iraci, Tim R. Mercer, Tommaso Leonardi, Emanuele Alpi, Denise Drago, Clara Alfaro-Cervello, Harpreet K. Saini, Matthew P. Davis, Julia Schaeffer, Beatriz Vega, Matilde Stefanini, CongJian Zhao, Werner Muller, Jose Manuel Garcia-Verdugo, Suresh Mathivanan, Angela Bachi, Anton J. Enright, John S. Mattick, Stefano Pluchino
Journal name Molecular Cell
Publication year 2014
Sample Neural stem cells
Sample name NPCs - Th1 treated
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Snrpd3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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