Gene description for Cops6
Gene name COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana)
Gene symbol Cops6
Other names/aliases Sgn3
VIP/MOV34
Species Mus musculus
 Database cross references - Cops6
ExoCarta ExoCarta_26893
Entrez Gene 26893
UniProt O88545  
 Cops6 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Cops6
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    cullin deneddylation GO:0010388 ISO
Subcellular Localization
    cytoplasm GO:0005737 IEA
    COP9 signalosome GO:0008180 ISO
    extracellular exosome GO:0070062 ISO
    nucleus GO:0005634 IEA
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Cops6 in exosomes
1
Experiment ID 210
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD81|FLOT1
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Cops6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cops6 is involved
No pathways found





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