Gene description for Gps1
Gene name
G protein pathway suppressor 1
Gene symbol
Gps1
Other names/aliases
Cops1 Csn1 R75577 Sgn1
Species
Mus musculus
Database cross references - Gps1
ExoCarta
ExoCarta_209318
Vesiclepedia
VP_209318
Entrez Gene
209318
Gps1 identified in exosomes derived from the following tissue/cell type
Melanoma cells
34957415
Melanoma cells
34957415
Gene ontology annotations for Gps1
Experiment description of studies that identified Gps1 in exosomes
1
Experiment ID
1117
MISEV standards
✘
Biophysical techniques
✔
Cd81|Icam1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
34957415
Organism
Mus musculus
Experiment description
Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism
Authors
"GarcÃa-Silva S, Benito-MartÃn A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÃ, Torres-Ruiz R, RodrÃguez-Perales S, MartÃnez L, Pérez-MartÃnez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, MartÃnez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, MegÃas D, Mehrara BJ, Lyden D, Peinado H."
Journal name
Nat Cancer
Publication year
2021
Sample
Melanoma cells
Sample name
B16-F1R2
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
1118
MISEV standards
✘
Biophysical techniques
✔
Cd81|Icam1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
34957415
Organism
Mus musculus
Experiment description
Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism
Authors
"GarcÃa-Silva S, Benito-MartÃn A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÃ, Torres-Ruiz R, RodrÃguez-Perales S, MartÃnez L, Pérez-MartÃnez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, MartÃnez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, MegÃas D, Mehrara BJ, Lyden D, Peinado H."
Journal name
Nat Cancer
Publication year
2021
Sample
Melanoma cells
Sample name
B16-F1R2
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for Gps1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
Skp1a
21402
Co-fractionation
Mus musculus
2
Cops5
26754
Affinity Capture-Western
Mus musculus
3
Ubc
Reconstituted Complex
Mus musculus
4
Tmem173
Proximity Label-MS
Mus musculus
5
CUL1
8454
Affinity Capture-MS
Homo sapiens
6
Cops4
26891
Affinity Capture-Western
Mus musculus
7
Cops7b
Affinity Capture-Western
Mus musculus
8
Cops3
Affinity Capture-Western
Mus musculus
9
Cops2
12848
Affinity Capture-Western
Mus musculus
Affinity Capture-Western
Mus musculus
10
Cops8
108679
Co-fractionation
Mus musculus
Affinity Capture-Western
Mus musculus
Affinity Capture-Western
Mus musculus
11
Cops7a
26894
Affinity Capture-Western
Mus musculus
12
Gsk3b
Biochemical Activity
Mus musculus
13
Chaf1a
Affinity Capture-MS
Mus musculus
14
Sap130
Affinity Capture-Western
Mus musculus
15
ASB4
Affinity Capture-Western
Homo sapiens
16
Cops6
26893
Affinity Capture-Western
Mus musculus
17
Epb4.1l2
13822
Co-fractionation
Mus musculus
18
Tmod1
Co-fractionation
Mus musculus
View the network
image/svg+xml
Pathways in which Gps1 is involved
No pathways found