Gene description for Hnrnpa3
Gene name heterogeneous nuclear ribonucleoprotein A3
Gene symbol Hnrnpa3
Other names/aliases 2410013L13Rik
2610209F03Rik
2610510D13Rik
Hnrpa3
Species Mus musculus
 Database cross references - Hnrnpa3
ExoCarta ExoCarta_229279
Entrez Gene 229279
UniProt Q8BG05  
 Hnrnpa3 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
Pancreatic cells 19351151    
 Gene ontology annotations for Hnrnpa3
Molecular Function
    RNA transmembrane transporter activity GO:0051033 ISO
    RNA binding GO:0003723 IEA
    nucleotide binding GO:0000166 IEA
    nucleic acid binding GO:0003676 IEA
    mRNA binding GO:0003729 ISO
Biological Process
    RNA splicing GO:0008380 IEA
    transmembrane transport GO:0055085 ISO
    mRNA transport GO:0051028 ISO
    mRNA processing GO:0006397 IEA
Subcellular Localization
    nucleus GO:0005634 ISO
    spliceosomal complex GO:0005681 IEA
    ribonucleoprotein granule GO:0035770 ISO
    cytoplasm GO:0005737 ISO
    neuron projection GO:0043005 ISO
    ribonucleoprotein complex GO:0030529 IEA
 Experiment description of studies that identified Hnrnpa3 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
2
Experiment ID 188
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH|UCHL1|HSP90
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Hnrnpa3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Hnrnpa3 is involved
PathwayEvidenceSource
mRNA Splicing - Major Pathway IEA Reactome
Processing of Capped Intron-Containing Pre-mRNA IEA Reactome





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