Gene description for Kpna3
Gene name
karyopherin (importin) alpha 3
Gene symbol
Kpna3
Other names/aliases
IPOA4
Species
Mus musculus
Database cross references - Kpna3
ExoCarta
ExoCarta_16648
Vesiclepedia
VP_16648
Entrez Gene
16648
UniProt
O35344
Kpna3 identified in sEVs derived from the following tissue/cell type
Colon cancer cells
37309723
T-cell lymphoma cells
37309723
Gene ontology annotations for Kpna3
Experiment description of studies that identified Kpna3 in sEVs
1
Experiment ID
907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
Colon cancer cells
Sample name
C26
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
T-cell lymphoma cells
Sample name
EL4
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for Kpna3
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
Foxp3
Affinity Capture-MS
Mus musculus
2
Kctd13
Affinity Capture-MS
Mus musculus
3
Hnrnpc
15381
Co-fractionation
Mus musculus
4
Atg16l1
Affinity Capture-MS
Mus musculus
5
Pou5f1
Affinity Capture-MS
Mus musculus
6
Chd8
Two-hybrid
Mus musculus
Affinity Capture-Western
Mus musculus
7
Kpna6
Co-fractionation
Mus musculus
View the network
image/svg+xml
Pathways in which Kpna3 is involved
No pathways found