Gene description for Pabpn1
Gene name poly(A) binding protein, nuclear 1
Gene symbol Pabpn1
Other names/aliases PAB2
Pabp3
mPABII
Species Mus musculus
 Database cross references - Pabpn1
ExoCarta ExoCarta_54196
Entrez Gene 54196
UniProt Q8CCS6  
 Pabpn1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Pabpn1
Molecular Function
    poly(A) RNA binding GO:0044822 ISO
    protein self-association GO:0043621 ISO
    RNA binding GO:0003723 IEA
    nucleotide binding GO:0000166 IEA
    nucleic acid binding GO:0003676 IEA
    poly(A) binding GO:0008143 TAS
Biological Process
    mRNA polyadenylation GO:0006378 TAS
    mRNA processing GO:0006397 IEA
    poly(A)+ mRNA export from nucleus GO:0016973 ISO
Subcellular Localization
    cytoplasm GO:0005737 IEA
    ribonucleoprotein complex GO:0030529 ISO
    nucleus GO:0005634 ISO
    nuclear inclusion body GO:0042405 ISO
 Experiment description of studies that identified Pabpn1 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Pabpn1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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